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Suspected chronic pancreatitis with normal MRCP: findings on MRI in correlation with secretin MRCP.
J Magn Reson Imaging. 2008 Jan; 27(1):125-31.JM

Abstract

PURPOSE

To review pancreatic MRI findings and their relationship with estimated pancreatic exocrine function on secretin-stimulated MR cholangiopancreatography (S-MRCP) in patients with clinically suspected chronic pancreatitis and normal baseline MRCP findings.

MATERIALS AND METHODS

MRI findings of 26 patients with normal pancreatic duct diameter and without side branch ectasia on MRCP were evaluated. A single radiologist assessed pancreatic size, pancreatic signal intensity ratio (SIR), and arterial enhancement ratio (A/V) at head, body, and tail of the pancreas on T(1)-weighted fat-suppressed and serial contrast-enhanced images at a single session. Combined findings were graded with a composite score. Serial S-MRCP was performed at the same session with standard MRI. Correlation and differences between MRI findings and associated grade of duodenal filling (DF) or the degree of pancreatic duct caliber change (PDC) were analyzed.

RESULTS

Seven patients revealed normal and 19 patients abnormal MRI findings. Significant correlation was present between the degree of DF and mean values of pancreatic size (r = 0.748), SIR (r = 0.610), A/V (r = 0.466), composite score (r = 0.833), and PDC (r = 0.554) separately. PDC correlated with SIR (r = 0.413) and composite score (r = 0.452), but not with A/V or pancreatic size. Significant differences were present between normal and abnormal DF grades in terms of mean values of associated findings of size (P = 0.001), SIR (P = 0.008), A/V (P = 0.019), and PDC (P = 0.001).

CONCLUSION

Patients with clinically suspected chronic pancreatitis and normal MRCP findings may have a spectrum of MRI findings that correlate with the estimated pancreatic exocrine insufficiency on S-MRCP with the increasing number of combined findings.

Authors+Show Affiliations

Department of Radiology, Saint Louis University Hospitals, St. Louis, Missouri 63110, USA. nc.balci@excite.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18058927

Citation

Balci, N Cem, et al. "Suspected Chronic Pancreatitis With Normal MRCP: Findings On MRI in Correlation With Secretin MRCP." Journal of Magnetic Resonance Imaging : JMRI, vol. 27, no. 1, 2008, pp. 125-31.
Balci NC, Alkaade S, Magas L, et al. Suspected chronic pancreatitis with normal MRCP: findings on MRI in correlation with secretin MRCP. J Magn Reson Imaging. 2008;27(1):125-31.
Balci, N. C., Alkaade, S., Magas, L., Momtahen, A. J., & Burton, F. R. (2008). Suspected chronic pancreatitis with normal MRCP: findings on MRI in correlation with secretin MRCP. Journal of Magnetic Resonance Imaging : JMRI, 27(1), 125-31.
Balci NC, et al. Suspected Chronic Pancreatitis With Normal MRCP: Findings On MRI in Correlation With Secretin MRCP. J Magn Reson Imaging. 2008;27(1):125-31. PubMed PMID: 18058927.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Suspected chronic pancreatitis with normal MRCP: findings on MRI in correlation with secretin MRCP. AU - Balci,N Cem, AU - Alkaade,Samer, AU - Magas,Louis, AU - Momtahen,Amir Javad, AU - Burton,Frank R, PY - 2007/12/7/pubmed PY - 2008/3/26/medline PY - 2007/12/7/entrez SP - 125 EP - 31 JF - Journal of magnetic resonance imaging : JMRI JO - J Magn Reson Imaging VL - 27 IS - 1 N2 - PURPOSE: To review pancreatic MRI findings and their relationship with estimated pancreatic exocrine function on secretin-stimulated MR cholangiopancreatography (S-MRCP) in patients with clinically suspected chronic pancreatitis and normal baseline MRCP findings. MATERIALS AND METHODS: MRI findings of 26 patients with normal pancreatic duct diameter and without side branch ectasia on MRCP were evaluated. A single radiologist assessed pancreatic size, pancreatic signal intensity ratio (SIR), and arterial enhancement ratio (A/V) at head, body, and tail of the pancreas on T(1)-weighted fat-suppressed and serial contrast-enhanced images at a single session. Combined findings were graded with a composite score. Serial S-MRCP was performed at the same session with standard MRI. Correlation and differences between MRI findings and associated grade of duodenal filling (DF) or the degree of pancreatic duct caliber change (PDC) were analyzed. RESULTS: Seven patients revealed normal and 19 patients abnormal MRI findings. Significant correlation was present between the degree of DF and mean values of pancreatic size (r = 0.748), SIR (r = 0.610), A/V (r = 0.466), composite score (r = 0.833), and PDC (r = 0.554) separately. PDC correlated with SIR (r = 0.413) and composite score (r = 0.452), but not with A/V or pancreatic size. Significant differences were present between normal and abnormal DF grades in terms of mean values of associated findings of size (P = 0.001), SIR (P = 0.008), A/V (P = 0.019), and PDC (P = 0.001). CONCLUSION: Patients with clinically suspected chronic pancreatitis and normal MRCP findings may have a spectrum of MRI findings that correlate with the estimated pancreatic exocrine insufficiency on S-MRCP with the increasing number of combined findings. SN - 1053-1807 UR - https://www.unboundmedicine.com/medline/citation/18058927/Suspected_chronic_pancreatitis_with_normal_MRCP:_findings_on_MRI_in_correlation_with_secretin_MRCP_ L2 - https://doi.org/10.1002/jmri.21241 DB - PRIME DP - Unbound Medicine ER -