Tags

Type your tag names separated by a space and hit enter

Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men.
Appl Physiol Nutr Metab. 2007 Dec; 32(6):1132-8.AP

Abstract

Whey protein is a supplemental protein source often used by athletes, particularly those aiming to gain muscle mass; however, direct evidence for its efficacy in stimulating muscle protein synthesis (MPS) is lacking. We aimed to determine the impact of consuming whey protein on skeletal muscle protein turnover in the post-exercise period. Eight healthy resistance-trained young men (age=21+/-1 .0 years; BMI=26.8+/-0.9 kg/m2 (means+/-SE)) participated in a double-blind randomized crossover trial in which they performed a unilateral leg resistance exercise workout (EX: 4 sets of knee extensions and 4 sets of leg press; 8-10 repetitions/set; 80% of maximal), such that one leg was not exercised and acted as a rested (RE) comparator. After exercise, subjects consumed either an isoenergetic whey protein plus carbohydrate beverage (WHEY: 10 g protein and 21 g fructose) or a carbohydrate-only beverage (CHO: 21 g fructose and 10 g maltodextran). Subjects received pulse-tracer injections of L-[ring-2H5]phenylalanine and L-[15N]phenylalanine to measure MPS. Exercise stimulated a rise in MPS in the WHEY-EX and CHO-EX legs, which were greater than MPS in the WHEY-RE leg and the CHO-RE leg (all p<0.05), respectively. The rate of MPS in the WHEY-EX leg was greater than in the CHO-EX leg (p<0.001). We conclude that a small dose (10 g) of whey protein with carbohydrate (21 g) can stimulate a rise in MPS after resistance exercise in trained young men that would be supportive of a positive net protein balance, which, over time, would lead to hypertrophy.

Authors+Show Affiliations

Exercise Metabolism Research Group, Department of Kinesiology, McMaster University, 1280 Main St. West, Hamilton, ON L8S 4K1, Canada.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

18059587

Citation

Tang, Jason E., et al. "Minimal Whey Protein With Carbohydrate Stimulates Muscle Protein Synthesis Following Resistance Exercise in Trained Young Men." Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme, vol. 32, no. 6, 2007, pp. 1132-8.
Tang JE, Manolakos JJ, Kujbida GW, et al. Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men. Appl Physiol Nutr Metab. 2007;32(6):1132-8.
Tang, J. E., Manolakos, J. J., Kujbida, G. W., Lysecki, P. J., Moore, D. R., & Phillips, S. M. (2007). Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men. Applied Physiology, Nutrition, and Metabolism = Physiologie Appliquee, Nutrition Et Metabolisme, 32(6), 1132-8.
Tang JE, et al. Minimal Whey Protein With Carbohydrate Stimulates Muscle Protein Synthesis Following Resistance Exercise in Trained Young Men. Appl Physiol Nutr Metab. 2007;32(6):1132-8. PubMed PMID: 18059587.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Minimal whey protein with carbohydrate stimulates muscle protein synthesis following resistance exercise in trained young men. AU - Tang,Jason E, AU - Manolakos,Joshua J, AU - Kujbida,Greg W, AU - Lysecki,Paul J, AU - Moore,Daniel R, AU - Phillips,Stuart M, PY - 2007/12/7/pubmed PY - 2008/3/12/medline PY - 2007/12/7/entrez SP - 1132 EP - 8 JF - Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme JO - Appl Physiol Nutr Metab VL - 32 IS - 6 N2 - Whey protein is a supplemental protein source often used by athletes, particularly those aiming to gain muscle mass; however, direct evidence for its efficacy in stimulating muscle protein synthesis (MPS) is lacking. We aimed to determine the impact of consuming whey protein on skeletal muscle protein turnover in the post-exercise period. Eight healthy resistance-trained young men (age=21+/-1 .0 years; BMI=26.8+/-0.9 kg/m2 (means+/-SE)) participated in a double-blind randomized crossover trial in which they performed a unilateral leg resistance exercise workout (EX: 4 sets of knee extensions and 4 sets of leg press; 8-10 repetitions/set; 80% of maximal), such that one leg was not exercised and acted as a rested (RE) comparator. After exercise, subjects consumed either an isoenergetic whey protein plus carbohydrate beverage (WHEY: 10 g protein and 21 g fructose) or a carbohydrate-only beverage (CHO: 21 g fructose and 10 g maltodextran). Subjects received pulse-tracer injections of L-[ring-2H5]phenylalanine and L-[15N]phenylalanine to measure MPS. Exercise stimulated a rise in MPS in the WHEY-EX and CHO-EX legs, which were greater than MPS in the WHEY-RE leg and the CHO-RE leg (all p<0.05), respectively. The rate of MPS in the WHEY-EX leg was greater than in the CHO-EX leg (p<0.001). We conclude that a small dose (10 g) of whey protein with carbohydrate (21 g) can stimulate a rise in MPS after resistance exercise in trained young men that would be supportive of a positive net protein balance, which, over time, would lead to hypertrophy. SN - 1715-5312 UR - https://www.unboundmedicine.com/medline/citation/18059587/Minimal_whey_protein_with_carbohydrate_stimulates_muscle_protein_synthesis_following_resistance_exercise_in_trained_young_men_ L2 - https://cdnsciencepub.com/doi/10.1139/H07-076?url_ver=Z39.88-2003&amp;rfr_id=ori:rid:crossref.org&amp;rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -