Tags

Type your tag names separated by a space and hit enter

Enantioselective organocatalytic substitution of alpha-cyanoacetates on imidoyl chlorides--synthesis of optically active ketimines.
Chem Commun (Camb). 2007 Dec 28CC

Abstract

The enantioselective substitution of alpha-cyanoacetates on imidoyl chlorides under phase-transfer catalytic conditions is presented; a simple quinidine-derived phase-transfer catalyst gives access to the products, highly substituted ketimines, in generally good yields and up to 90% ee.

Authors+Show Affiliations

Santoro S
Danish National Research Foundation: Center for Catalysis, Department of Chemistry, Aarhus University, Aarhus C, Denmark.
Poulsen TB
No affiliation info available
Jørgensen KA
No affiliation info available

MeSH

AcetatesCatalysisCrystallography, X-RayIminesModels, MolecularMolecular StructureNitrilesPhase TransitionStereoisomerism

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18060126

Citation

Santoro, Stefano, et al. "Enantioselective Organocatalytic Substitution of Alpha-cyanoacetates On Imidoyl Chlorides--synthesis of Optically Active Ketimines." Chemical Communications (Cambridge, England), 2007, pp. 5155-7.
Santoro S, Poulsen TB, Jørgensen KA. Enantioselective organocatalytic substitution of alpha-cyanoacetates on imidoyl chlorides--synthesis of optically active ketimines. Chem Commun (Camb). 2007.
Santoro, S., Poulsen, T. B., & Jørgensen, K. A. (2007). Enantioselective organocatalytic substitution of alpha-cyanoacetates on imidoyl chlorides--synthesis of optically active ketimines. Chemical Communications (Cambridge, England), (48), 5155-7.
Santoro S, Poulsen TB, Jørgensen KA. Enantioselective Organocatalytic Substitution of Alpha-cyanoacetates On Imidoyl Chlorides--synthesis of Optically Active Ketimines. Chem Commun (Camb). 2007 Dec 28;(48)5155-7. PubMed PMID: 18060126.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Enantioselective organocatalytic substitution of alpha-cyanoacetates on imidoyl chlorides--synthesis of optically active ketimines. AU - Santoro,Stefano, AU - Poulsen,Thomas B, AU - Jørgensen,Karl Anker, Y1 - 2007/11/16/ PY - 2007/12/7/pubmed PY - 2008/3/5/medline PY - 2007/12/7/entrez SP - 5155 EP - 7 JF - Chemical communications (Cambridge, England) JO - Chem Commun (Camb) IS - 48 N2 - The enantioselective substitution of alpha-cyanoacetates on imidoyl chlorides under phase-transfer catalytic conditions is presented; a simple quinidine-derived phase-transfer catalyst gives access to the products, highly substituted ketimines, in generally good yields and up to 90% ee. SN - 1359-7345 UR - https://www.unboundmedicine.com/medline/citation/18060126/Enantioselective_organocatalytic_substitution_of_alpha_cyanoacetates_on_imidoyl_chlorides__synthesis_of_optically_active_ketimines_ DB - PRIME DP - Unbound Medicine ER -