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Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol.
Res Vet Sci. 2008 Oct; 85(2):227-32.RV

Abstract

The aim of this study was to evaluate the correlation between the cerebral state index (CSI) and the estimated propofol plasma concentrations in dogs during induction of anaesthesia. Fifteen healthy dogs undergoing scheduled routine surgical procedures were enrolled in this study. Target controlled infusion (TCI) software, based on the pharmacokinetic model for propofol, was used to control the syringe pump and to estimate plasma propofol concentrations (PropCp) and the CSI values every five-seconds. Three electrodes placed in the centre of the forehead, on the left side of the forehead and on the left mastoid were used to collect the electroencephalographic (EEG) signal converted by the cerebral state monitor into the CSI. The cerebral electrical changes induced by increasing propofol concentrations appear to be detected by CSI monitoring in dogs. The negative correlation between CSI and PropCp demonstrates that the CSI could be used to assess electrical brain activity in dogs during the induction of anaesthesia with propofol.

Authors+Show Affiliations

Hospital veterinário do Porto, Porto, Portugal. lenioribeiro@hospvetporto.ptNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

18061223

Citation

Ribeiro, Lénio M., et al. "Brain Monitoring in Dogs Using the Cerebral State Index During the Induction of Anaesthesia Via Target-controlled Infusion of Propofol." Research in Veterinary Science, vol. 85, no. 2, 2008, pp. 227-32.
Ribeiro LM, Ferreira DA, Bressan NM, et al. Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol. Res Vet Sci. 2008;85(2):227-32.
Ribeiro, L. M., Ferreira, D. A., Bressan, N. M., Nunes, C. S., Amorim, P., & Antunes, L. M. (2008). Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol. Research in Veterinary Science, 85(2), 227-32.
Ribeiro LM, et al. Brain Monitoring in Dogs Using the Cerebral State Index During the Induction of Anaesthesia Via Target-controlled Infusion of Propofol. Res Vet Sci. 2008;85(2):227-32. PubMed PMID: 18061223.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Brain monitoring in dogs using the cerebral state index during the induction of anaesthesia via target-controlled infusion of propofol. AU - Ribeiro,Lénio M, AU - Ferreira,David A, AU - Bressan,Nadja M, AU - Nunes,Catarina S, AU - Amorim,Pedro, AU - Antunes,Luis M, Y1 - 2007/12/03/ PY - 2007/02/09/received PY - 2007/10/15/revised PY - 2007/10/19/accepted PY - 2007/12/7/pubmed PY - 2008/11/4/medline PY - 2007/12/7/entrez SP - 227 EP - 32 JF - Research in veterinary science JO - Res Vet Sci VL - 85 IS - 2 N2 - The aim of this study was to evaluate the correlation between the cerebral state index (CSI) and the estimated propofol plasma concentrations in dogs during induction of anaesthesia. Fifteen healthy dogs undergoing scheduled routine surgical procedures were enrolled in this study. Target controlled infusion (TCI) software, based on the pharmacokinetic model for propofol, was used to control the syringe pump and to estimate plasma propofol concentrations (PropCp) and the CSI values every five-seconds. Three electrodes placed in the centre of the forehead, on the left side of the forehead and on the left mastoid were used to collect the electroencephalographic (EEG) signal converted by the cerebral state monitor into the CSI. The cerebral electrical changes induced by increasing propofol concentrations appear to be detected by CSI monitoring in dogs. The negative correlation between CSI and PropCp demonstrates that the CSI could be used to assess electrical brain activity in dogs during the induction of anaesthesia with propofol. SN - 0034-5288 UR - https://www.unboundmedicine.com/medline/citation/18061223/Brain_monitoring_in_dogs_using_the_cerebral_state_index_during_the_induction_of_anaesthesia_via_target_controlled_infusion_of_propofol_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S0034-5288(07)00245-7 DB - PRIME DP - Unbound Medicine ER -