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Factors associated with foveoschisis and foveal detachment without macular hole in high myopia.
Eye (Lond). 2009 Feb; 23(2):356-61.E

Abstract

PURPOSE

To investigate the associated factors of foveoschisis and foveal detachment without macular hole in highly myopic eyes.

METHODS

A cross-sectional study of 124 eyes of 68 highly myopic patients was performed. The patients underwent complete ocular examination, fundus photography, and optical coherence tomography (OCT).

RESULTS

Of the 124 eyes, 10 (8%, 10/124) had foveoschisis or foveal detachment without a macular hole on OCT examination. On the basis of univariate analysis, six variables were associated with the pathologic changes, including age over 40 years (P=0.018), spherical equivalent over 10 D (P=0.042), axial length over 31 mm (P=0.001), macular chorioretinal atrophy (P=0.00003), posterior staphyloma (P=0.0003), and vitreoretinal interface factors, including epiretinal membrane, posterior vitreoschisis, and vitreomacular traction (P=0.00002). In the multivariate analysis, three factors were independently associated with foveoschisis and foveal detachment without macular hole in high myopia: axial length, macular chorioretinal atrophy, and vitreoretinal interface factors.

CONCLUSIONS

Foveoschisis and foveal detachment without macular hole are sight-threatening disorders in highly myopic eyes. Axial length, macular chorioretinal atrophy, and vitreoretinal interface factors were independently associated with these pathological conditions. Thus, both intraocular and outer ocular wall factors play important roles and merit further study.

Authors+Show Affiliations

Department of Ophthalmology, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Taiwan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18064059

Citation

Wu, P-C, et al. "Factors Associated With Foveoschisis and Foveal Detachment Without Macular Hole in High Myopia." Eye (London, England), vol. 23, no. 2, 2009, pp. 356-61.
Wu PC, Chen YJ, Chen YH, et al. Factors associated with foveoschisis and foveal detachment without macular hole in high myopia. Eye (Lond). 2009;23(2):356-61.
Wu, P. C., Chen, Y. J., Chen, Y. H., Chen, C. H., Shin, S. J., Tsai, C. L., & Kuo, H. K. (2009). Factors associated with foveoschisis and foveal detachment without macular hole in high myopia. Eye (London, England), 23(2), 356-61.
Wu PC, et al. Factors Associated With Foveoschisis and Foveal Detachment Without Macular Hole in High Myopia. Eye (Lond). 2009;23(2):356-61. PubMed PMID: 18064059.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Factors associated with foveoschisis and foveal detachment without macular hole in high myopia. AU - Wu,P-C, AU - Chen,Y-J, AU - Chen,Y-H, AU - Chen,C-H, AU - Shin,S-J, AU - Tsai,C-L, AU - Kuo,H-K, Y1 - 2007/12/07/ PY - 2007/12/8/pubmed PY - 2010/1/8/medline PY - 2007/12/8/entrez SP - 356 EP - 61 JF - Eye (London, England) JO - Eye (Lond) VL - 23 IS - 2 N2 - PURPOSE: To investigate the associated factors of foveoschisis and foveal detachment without macular hole in highly myopic eyes. METHODS: A cross-sectional study of 124 eyes of 68 highly myopic patients was performed. The patients underwent complete ocular examination, fundus photography, and optical coherence tomography (OCT). RESULTS: Of the 124 eyes, 10 (8%, 10/124) had foveoschisis or foveal detachment without a macular hole on OCT examination. On the basis of univariate analysis, six variables were associated with the pathologic changes, including age over 40 years (P=0.018), spherical equivalent over 10 D (P=0.042), axial length over 31 mm (P=0.001), macular chorioretinal atrophy (P=0.00003), posterior staphyloma (P=0.0003), and vitreoretinal interface factors, including epiretinal membrane, posterior vitreoschisis, and vitreomacular traction (P=0.00002). In the multivariate analysis, three factors were independently associated with foveoschisis and foveal detachment without macular hole in high myopia: axial length, macular chorioretinal atrophy, and vitreoretinal interface factors. CONCLUSIONS: Foveoschisis and foveal detachment without macular hole are sight-threatening disorders in highly myopic eyes. Axial length, macular chorioretinal atrophy, and vitreoretinal interface factors were independently associated with these pathological conditions. Thus, both intraocular and outer ocular wall factors play important roles and merit further study. SN - 1476-5454 UR - https://www.unboundmedicine.com/medline/citation/18064059/Factors_associated_with_foveoschisis_and_foveal_detachment_without_macular_hole_in_high_myopia_ L2 - http://dx.doi.org/10.1038/sj.eye.6703038 DB - PRIME DP - Unbound Medicine ER -