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Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children.
Anadolu Kardiyol Derg. 2007 Dec; 7(4):415-20.AK

Abstract

OBJECTIVE

Early detection of dyslipidemia and long-term prevention of atherosclerosis by controlling risk factors should begin in childhood. The purpose of this study was to evaluate the prevalence of dyslipidemia according to non-high density lipoprotein cholesterol (non-HDL-C) levels in children and also evaluate serum non-HDL-C levels according to age groups, gender difference and living areas.

METHODS

Overall, 2896 children (1467 girls, 1429 boys) aged between 7-18 years, residing in urban and rural parts of Eskişehir, Turkey, were enrolled in this randomized cross-sectional study. Serum non-HDL-C, total cholesterol (TC) and triglyceride (TG) levels were assessed in all participants of the study. Statistical analysis was performed Student's independent-samples T test for comparison of lipid parameters and relations between lipid parameters and age, anthropometric measurements, body fat percentage were evaluated by Pearson correlation test.

RESULTS

Serum non-HDL-C levels were significantly higher in girls (115.5+/-31.5mg/dl) than boys (106.7+/-30.2 mg/Dl) (p<0.001). For girls, serum non-HDL-C levels were higher in 7-10 year age group than in 11-14-year and 15-18-year age groups (p<0.01 and p<0.05, respectively). For boys serum non-HDL-C levels of 7-10 year age group were significantly higher than in 11-14-year and 15-18-year age groups (p<0.001 for both). Serum non-HDL-C, total cholesterol and triglyceride levels were higher in girls than in boys especially in the 7-10-year-old age group. Serum TC, LDL-C, and HDL-C levels were higher in urban area residents, while serum TG levels were higher in rural area residents (p<0.001). Serum non-HDL-C levels were similar in residents of different living areas (p>0.05). In both sexes, non-HDL-C levels positively correlated with age and lipid parameters except HDL-C levels and also negatively correlated with HDL-C levels. In boys, non-HDL-C levels also correlated with total body fat percentage, weight, height. The prevalence of dyslipidemia according to non-HDL-C levels was higher (13.2%) in girls than boys (8.9%) (p<0.001). The prevalence of elevated non-HDL-C levels was higher in urban area residents than in rural area residents (p<0.05). The dyslipidemia prevalence according to non-HDL-C levels was similar with dyslipidemia prevalence according to serum LDL-C levels.

CONCLUSION

Our results are indicative of the prevalence of dyslipidemia in children is considerably common in our population. Serum non-HDL-C levels could be used as an appropriate tool for detecting dyslipidemia in childhood.

Authors+Show Affiliations

Department of Pediatrics, Faculty of Medicine, Eskişehir Osmangazi University, TR-26480 Eskişehir, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18065339

Citation

Uçar, Birsen, et al. "Serum Lipid Profiles Including Non-high Density Lipoprotein Cholesterol Levels in Turkish School-children." Anadolu Kardiyoloji Dergisi : AKD = the Anatolian Journal of Cardiology, vol. 7, no. 4, 2007, pp. 415-20.
Uçar B, Kiliç Z, Dinleyici EC, et al. Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children. Anadolu Kardiyol Derg. 2007;7(4):415-20.
Uçar, B., Kiliç, Z., Dinleyici, E. C., Colak, O., & Güneş, E. (2007). Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children. Anadolu Kardiyoloji Dergisi : AKD = the Anatolian Journal of Cardiology, 7(4), 415-20.
Uçar B, et al. Serum Lipid Profiles Including Non-high Density Lipoprotein Cholesterol Levels in Turkish School-children. Anadolu Kardiyol Derg. 2007;7(4):415-20. PubMed PMID: 18065339.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Serum lipid profiles including non-high density lipoprotein cholesterol levels in Turkish school-children. AU - Uçar,Birsen, AU - Kiliç,Zübeyir, AU - Dinleyici,Ener Cağri, AU - Colak,Omer, AU - Güneş,Erdoğan, PY - 2007/12/11/pubmed PY - 2008/1/11/medline PY - 2007/12/11/entrez SP - 415 EP - 20 JF - Anadolu kardiyoloji dergisi : AKD = the Anatolian journal of cardiology JO - Anadolu Kardiyol Derg VL - 7 IS - 4 N2 - OBJECTIVE: Early detection of dyslipidemia and long-term prevention of atherosclerosis by controlling risk factors should begin in childhood. The purpose of this study was to evaluate the prevalence of dyslipidemia according to non-high density lipoprotein cholesterol (non-HDL-C) levels in children and also evaluate serum non-HDL-C levels according to age groups, gender difference and living areas. METHODS: Overall, 2896 children (1467 girls, 1429 boys) aged between 7-18 years, residing in urban and rural parts of Eskişehir, Turkey, were enrolled in this randomized cross-sectional study. Serum non-HDL-C, total cholesterol (TC) and triglyceride (TG) levels were assessed in all participants of the study. Statistical analysis was performed Student's independent-samples T test for comparison of lipid parameters and relations between lipid parameters and age, anthropometric measurements, body fat percentage were evaluated by Pearson correlation test. RESULTS: Serum non-HDL-C levels were significantly higher in girls (115.5+/-31.5mg/dl) than boys (106.7+/-30.2 mg/Dl) (p<0.001). For girls, serum non-HDL-C levels were higher in 7-10 year age group than in 11-14-year and 15-18-year age groups (p<0.01 and p<0.05, respectively). For boys serum non-HDL-C levels of 7-10 year age group were significantly higher than in 11-14-year and 15-18-year age groups (p<0.001 for both). Serum non-HDL-C, total cholesterol and triglyceride levels were higher in girls than in boys especially in the 7-10-year-old age group. Serum TC, LDL-C, and HDL-C levels were higher in urban area residents, while serum TG levels were higher in rural area residents (p<0.001). Serum non-HDL-C levels were similar in residents of different living areas (p>0.05). In both sexes, non-HDL-C levels positively correlated with age and lipid parameters except HDL-C levels and also negatively correlated with HDL-C levels. In boys, non-HDL-C levels also correlated with total body fat percentage, weight, height. The prevalence of dyslipidemia according to non-HDL-C levels was higher (13.2%) in girls than boys (8.9%) (p<0.001). The prevalence of elevated non-HDL-C levels was higher in urban area residents than in rural area residents (p<0.05). The dyslipidemia prevalence according to non-HDL-C levels was similar with dyslipidemia prevalence according to serum LDL-C levels. CONCLUSION: Our results are indicative of the prevalence of dyslipidemia in children is considerably common in our population. Serum non-HDL-C levels could be used as an appropriate tool for detecting dyslipidemia in childhood. SN - 1308-0032 UR - https://www.unboundmedicine.com/medline/citation/18065339/Serum_lipid_profiles_including_non_high_density_lipoprotein_cholesterol_levels_in_Turkish_school_children_ L2 - http://www.anatoljcardiol.com/linkout/?PMID=18065339 DB - PRIME DP - Unbound Medicine ER -