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[Ultrasound-guided core needle biopsy in the diagnosis of breast lesions].
Zhonghua Wai Ke Za Zhi. 2007 Sep 01; 45(17):1185-7.ZW

Abstract

OBJECTIVE

To evaluate the accuracy and utility of ultrasound-guided core needle biopsy (CNB) in the diagnoses of breast lesions.

METHODS

The clinical data of 2152 consecutive breast lesions examined by CNB were reviewed. The histological agreement between core pathology and subsequent excision pathology was studied. The benign diseases without repeat biopsy were followed up.

RESULTS

There were 1461 cancers in final diagnosis among 2152 breast lesions, 1339 cancers were diagnosed by CNB. The false-negative rate of CNB was 3.5% (51/1461), and the underestimation rate was 4.9% (71/1461). In the repeat biopsy, carcinoma was found in 17 (50.0%) of 34 atypical ductal hyperplasia lesions and 25 (46.3%) of 54 papillary lesions. In 1461 cancers, the false-negative rate of ultrasound-guided CNB (2.1%, 22/1068) was significantly lower than that of free-hand-guided CNB (7.4%, 29/393) (P < 0.05). The false-negative rate of two special doctors for CNB (1.2%, 8/681) was significantly lower than that of other doctors (5.5%, 43/780) (P < 0.05). In 738 of benign lesions, 417 cases were excised and 50 malignant lesions were found, 205 cases were followed up by 2 - 29 months (median, 10.2 months), and one malignant lesion was found.

CONCLUSIONS

Ultrasound-guided core needle biopsy with histopathological assessment is an accurate method in diagnosis of breast lesions. Excisional biopsy is required to the high-risk lesions in CNB.

Authors+Show Affiliations

Breast Cancer Unit, Peking University School of Oncology, Beijing Cancer Hospital and Institute, Beijing 100036, China. zhqfan@sina.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

18067713

Citation

Fan, Zhao-qing, et al. "[Ultrasound-guided Core Needle Biopsy in the Diagnosis of Breast Lesions]." Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], vol. 45, no. 17, 2007, pp. 1185-7.
Fan ZQ, Ouyang T, Wang TF, et al. [Ultrasound-guided core needle biopsy in the diagnosis of breast lesions]. Zhonghua Wai Ke Za Zhi. 2007;45(17):1185-7.
Fan, Z. Q., Ouyang, T., Wang, T. F., Li, J. F., Xie, Y. T., Fan, T., Zhang, Z., & Lin, B. Y. (2007). [Ultrasound-guided core needle biopsy in the diagnosis of breast lesions]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery], 45(17), 1185-7.
Fan ZQ, et al. [Ultrasound-guided Core Needle Biopsy in the Diagnosis of Breast Lesions]. Zhonghua Wai Ke Za Zhi. 2007 Sep 1;45(17):1185-7. PubMed PMID: 18067713.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Ultrasound-guided core needle biopsy in the diagnosis of breast lesions]. AU - Fan,Zhao-qing, AU - Ouyang,Tao, AU - Wang,Tian-feng, AU - Li,Jin-feng, AU - Xie,Yun-tao, AU - Fan,Tie, AU - Zhang,Zhe, AU - Lin,Ben-yao, PY - 2007/12/11/pubmed PY - 2008/10/22/medline PY - 2007/12/11/entrez SP - 1185 EP - 7 JF - Zhonghua wai ke za zhi [Chinese journal of surgery] JO - Zhonghua Wai Ke Za Zhi VL - 45 IS - 17 N2 - OBJECTIVE: To evaluate the accuracy and utility of ultrasound-guided core needle biopsy (CNB) in the diagnoses of breast lesions. METHODS: The clinical data of 2152 consecutive breast lesions examined by CNB were reviewed. The histological agreement between core pathology and subsequent excision pathology was studied. The benign diseases without repeat biopsy were followed up. RESULTS: There were 1461 cancers in final diagnosis among 2152 breast lesions, 1339 cancers were diagnosed by CNB. The false-negative rate of CNB was 3.5% (51/1461), and the underestimation rate was 4.9% (71/1461). In the repeat biopsy, carcinoma was found in 17 (50.0%) of 34 atypical ductal hyperplasia lesions and 25 (46.3%) of 54 papillary lesions. In 1461 cancers, the false-negative rate of ultrasound-guided CNB (2.1%, 22/1068) was significantly lower than that of free-hand-guided CNB (7.4%, 29/393) (P < 0.05). The false-negative rate of two special doctors for CNB (1.2%, 8/681) was significantly lower than that of other doctors (5.5%, 43/780) (P < 0.05). In 738 of benign lesions, 417 cases were excised and 50 malignant lesions were found, 205 cases were followed up by 2 - 29 months (median, 10.2 months), and one malignant lesion was found. CONCLUSIONS: Ultrasound-guided core needle biopsy with histopathological assessment is an accurate method in diagnosis of breast lesions. Excisional biopsy is required to the high-risk lesions in CNB. SN - 0529-5815 UR - https://www.unboundmedicine.com/medline/citation/18067713/[Ultrasound_guided_core_needle_biopsy_in_the_diagnosis_of_breast_lesions]_ L2 - http://journal.yiigle.com/LinkIn.do?linkin_type=pubmed&amp;issn=0529-5815&amp;year=2007&amp;vol=45&amp;issue=17&amp;fpage=1185 DB - PRIME DP - Unbound Medicine ER -