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Active components and clinical applications of olive oil.
Altern Med Rev. 2007 Dec; 12(4):331-42.AM

Abstract

The olive tree, Olea europaea, is native to the Mediterranean basin and parts of Asia Minor. The fruit and compression-extracted oil have a wide range of therapeutic and culinary applications. Olive oil also constitutes a major component of the "Mediterranean diet." The chief active components of olive oil include oleic acid, phenolic constituents, and squalene. The main phenolics include hydroxytyrosol, tyrosol, and oleuropein, which occur in highest levels in virgin olive oil and have demonstrated antioxidant activity. Antioxidants are believed to be responsible for a number of olive oil's biological activities. Oleic acid, a monounsaturated fatty acid, has shown activity in cancer prevention, while squalene has also been identified as having anticancer effects. Olive oil consumption has benefit for colon and breast cancer prevention. The oil has been widely studied for its effects on coronary heart disease (CHD), specifically for its ability to reduce blood pressure and low-density lipoprotein (LDL) cholesterol. Antimicrobial activity of hydroxytyrosol, tyrosol, and oleuropein has been demonstrated against several strains of bacteria implicated in intestinal and respiratory infections. Although the majority of research has been conducted on the oil, consumption of whole olives might also confer health benefits.

Authors+Show Affiliations

Leeds General Hospital, Leeds, UK.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18069902

Citation

Waterman, Emily, and Brian Lockwood. "Active Components and Clinical Applications of Olive Oil." Alternative Medicine Review : a Journal of Clinical Therapeutic, vol. 12, no. 4, 2007, pp. 331-42.
Waterman E, Lockwood B. Active components and clinical applications of olive oil. Altern Med Rev. 2007;12(4):331-42.
Waterman, E., & Lockwood, B. (2007). Active components and clinical applications of olive oil. Alternative Medicine Review : a Journal of Clinical Therapeutic, 12(4), 331-42.
Waterman E, Lockwood B. Active Components and Clinical Applications of Olive Oil. Altern Med Rev. 2007;12(4):331-42. PubMed PMID: 18069902.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Active components and clinical applications of olive oil. AU - Waterman,Emily, AU - Lockwood,Brian, PY - 2007/12/12/pubmed PY - 2008/2/22/medline PY - 2007/12/12/entrez SP - 331 EP - 42 JF - Alternative medicine review : a journal of clinical therapeutic JO - Altern Med Rev VL - 12 IS - 4 N2 - The olive tree, Olea europaea, is native to the Mediterranean basin and parts of Asia Minor. The fruit and compression-extracted oil have a wide range of therapeutic and culinary applications. Olive oil also constitutes a major component of the "Mediterranean diet." The chief active components of olive oil include oleic acid, phenolic constituents, and squalene. The main phenolics include hydroxytyrosol, tyrosol, and oleuropein, which occur in highest levels in virgin olive oil and have demonstrated antioxidant activity. Antioxidants are believed to be responsible for a number of olive oil's biological activities. Oleic acid, a monounsaturated fatty acid, has shown activity in cancer prevention, while squalene has also been identified as having anticancer effects. Olive oil consumption has benefit for colon and breast cancer prevention. The oil has been widely studied for its effects on coronary heart disease (CHD), specifically for its ability to reduce blood pressure and low-density lipoprotein (LDL) cholesterol. Antimicrobial activity of hydroxytyrosol, tyrosol, and oleuropein has been demonstrated against several strains of bacteria implicated in intestinal and respiratory infections. Although the majority of research has been conducted on the oil, consumption of whole olives might also confer health benefits. SN - 1089-5159 UR - https://www.unboundmedicine.com/medline/citation/18069902/Active_components_and_clinical_applications_of_olive_oil_ L2 - http://archive.foundationalmedicinereview.com/publications/12/4/331.pdf DB - PRIME DP - Unbound Medicine ER -