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Multi-site testing with a point-of-care nerve conduction device can be used in an algorithm to diagnose diabetic sensorimotor polyneuropathy.
Diabetes Care. 2008 Mar; 31(3):522-4.DC

Abstract

OBJECTIVE

We aimed to establish whether multi-nerve testing with a point-of-care nerve conduction device could be used to diagnose diabetic sensorimotor polyneuropathy.

RESEARCH DESIGN AND METHODS

A total of 72 consecutive patients with diabetes underwent a full neurological examination and a concurrent evaluation for nine standard electrophysiological parameters using conventional nerve conduction studies (the reference standard) and a point-of-care device.

RESULTS

Spearman coefficients for correlation of point-of-care and conventional parameters ranged between 0.76 and 0.91 (P < 0.001 in all comparisons). Agreement by the method of Bland and Altman was acceptable despite small systematic biases. Fifty subjects (69%) had neuropathy according to conventional criteria. The sensitivity and specificity for the point-of-care device to identify such neuropathy was 88 and 82%, respectively.

CONCLUSIONS

A novel point-of-care device has reasonable diagnostic accuracy and thus may represent a sufficiently accurate alternative for detecting the diffuse electrophysiological criteria necessary to make the diagnosis of diabetic sensorimotor polyneuropathy.

Authors+Show Affiliations

Division of Endocrinology, University Health Network, University of Toronto, Toronto, Ontario, Canada. bruce.perkins@uhn.on.caNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18070992

Citation

Perkins, Bruce A., et al. "Multi-site Testing With a Point-of-care Nerve Conduction Device Can Be Used in an Algorithm to Diagnose Diabetic Sensorimotor Polyneuropathy." Diabetes Care, vol. 31, no. 3, 2008, pp. 522-4.
Perkins BA, Orszag A, Grewal J, et al. Multi-site testing with a point-of-care nerve conduction device can be used in an algorithm to diagnose diabetic sensorimotor polyneuropathy. Diabetes Care. 2008;31(3):522-4.
Perkins, B. A., Orszag, A., Grewal, J., Ng, E., Ngo, M., & Bril, V. (2008). Multi-site testing with a point-of-care nerve conduction device can be used in an algorithm to diagnose diabetic sensorimotor polyneuropathy. Diabetes Care, 31(3), 522-4.
Perkins BA, et al. Multi-site Testing With a Point-of-care Nerve Conduction Device Can Be Used in an Algorithm to Diagnose Diabetic Sensorimotor Polyneuropathy. Diabetes Care. 2008;31(3):522-4. PubMed PMID: 18070992.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Multi-site testing with a point-of-care nerve conduction device can be used in an algorithm to diagnose diabetic sensorimotor polyneuropathy. AU - Perkins,Bruce A, AU - Orszag,Andrej, AU - Grewal,Jaspreet, AU - Ng,Eduardo, AU - Ngo,Mylan, AU - Bril,Vera, Y1 - 2007/12/10/ PY - 2007/12/12/pubmed PY - 2008/6/3/medline PY - 2007/12/12/entrez SP - 522 EP - 4 JF - Diabetes care JO - Diabetes Care VL - 31 IS - 3 N2 - OBJECTIVE: We aimed to establish whether multi-nerve testing with a point-of-care nerve conduction device could be used to diagnose diabetic sensorimotor polyneuropathy. RESEARCH DESIGN AND METHODS: A total of 72 consecutive patients with diabetes underwent a full neurological examination and a concurrent evaluation for nine standard electrophysiological parameters using conventional nerve conduction studies (the reference standard) and a point-of-care device. RESULTS: Spearman coefficients for correlation of point-of-care and conventional parameters ranged between 0.76 and 0.91 (P < 0.001 in all comparisons). Agreement by the method of Bland and Altman was acceptable despite small systematic biases. Fifty subjects (69%) had neuropathy according to conventional criteria. The sensitivity and specificity for the point-of-care device to identify such neuropathy was 88 and 82%, respectively. CONCLUSIONS: A novel point-of-care device has reasonable diagnostic accuracy and thus may represent a sufficiently accurate alternative for detecting the diffuse electrophysiological criteria necessary to make the diagnosis of diabetic sensorimotor polyneuropathy. SN - 1935-5548 UR - https://www.unboundmedicine.com/medline/citation/18070992/Multi_site_testing_with_a_point_of_care_nerve_conduction_device_can_be_used_in_an_algorithm_to_diagnose_diabetic_sensorimotor_polyneuropathy_ L2 - http://care.diabetesjournals.org/cgi/pmidlookup?view=long&amp;pmid=18070992 DB - PRIME DP - Unbound Medicine ER -