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Value of magnifying chromoendoscopy and narrow band imaging (NBI) in classifying colorectal polyps: a prospective controlled study.
Endoscopy. 2007 Dec; 39(12):1092-6.E

Abstract

BACKGROUND AND STUDY AIMS

Chromoendoscopy in combination with magnifying endoscopy is useful in distinguishing neoplastic from non-neoplastic colorectal polyps. Narrow band imaging (NBI) has been developed as a new technique to differentiate tissue patterns in vivo. The aim of the present study was to directly compare the diagnostic values of chromoendoscopy and NBI for the differentiation of neoplastic from non-neoplastic colorectal polyps.

PATIENTS AND METHODS

In total, 200 colorectal polyps from 99 patients were distributed in a 1 : 1 ratio in order to analyze the surface according to the pit pattern classification and vascular patterns by either magnifying chromoendoscopy or NBI magnification. Histologic analysis was performed on all lesions.

RESULTS

Using the Kudo classification of mucosal patterns, NBI with magnification resulted in a sensitivity of 90.5 % and a specificity of 89.2 % for the differentiation of neoplastic vs. non-neoplastic lesions. This performance was comparable to magnifying chromoendoscopy with a sensitivity of 91.7 % and a specificity of 90 %, respectively. Using vascular patterns for differentiation, NBI with magnification correctly identified 93.7 % of neoplastic polyps and 89.2 % of non-neoplastic colorectal lesions, whereas magnifying chromoendoscopy had a specificity of 95 % but a sensitivity of only 66.7 %.

CONCLUSION

NBI in combination with magnifying endoscopy is a promising tool for the differentiation of neoplastic from non-neoplastic colorectal polyps in vivo without the necessity of using dye. The detection of capillary vessels with NBI allows the evaluation of colorectal lesions based on the vascular patterns with high diagnostic accuracy.

Authors+Show Affiliations

Medical Department III (Gastroenterology, Hepatology and Metabolic Diseases), University Hospital Aachen, Germany.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Controlled Clinical Trial
Journal Article

Language

eng

PubMed ID

18072061

Citation

Tischendorf, J J W., et al. "Value of Magnifying Chromoendoscopy and Narrow Band Imaging (NBI) in Classifying Colorectal Polyps: a Prospective Controlled Study." Endoscopy, vol. 39, no. 12, 2007, pp. 1092-6.
Tischendorf JJ, Wasmuth HE, Koch A, et al. Value of magnifying chromoendoscopy and narrow band imaging (NBI) in classifying colorectal polyps: a prospective controlled study. Endoscopy. 2007;39(12):1092-6.
Tischendorf, J. J., Wasmuth, H. E., Koch, A., Hecker, H., Trautwein, C., & Winograd, R. (2007). Value of magnifying chromoendoscopy and narrow band imaging (NBI) in classifying colorectal polyps: a prospective controlled study. Endoscopy, 39(12), 1092-6.
Tischendorf JJ, et al. Value of Magnifying Chromoendoscopy and Narrow Band Imaging (NBI) in Classifying Colorectal Polyps: a Prospective Controlled Study. Endoscopy. 2007;39(12):1092-6. PubMed PMID: 18072061.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Value of magnifying chromoendoscopy and narrow band imaging (NBI) in classifying colorectal polyps: a prospective controlled study. AU - Tischendorf,J J W, AU - Wasmuth,H E, AU - Koch,A, AU - Hecker,H, AU - Trautwein,C, AU - Winograd,R, PY - 2007/12/12/pubmed PY - 2008/1/29/medline PY - 2007/12/12/entrez SP - 1092 EP - 6 JF - Endoscopy JO - Endoscopy VL - 39 IS - 12 N2 - BACKGROUND AND STUDY AIMS: Chromoendoscopy in combination with magnifying endoscopy is useful in distinguishing neoplastic from non-neoplastic colorectal polyps. Narrow band imaging (NBI) has been developed as a new technique to differentiate tissue patterns in vivo. The aim of the present study was to directly compare the diagnostic values of chromoendoscopy and NBI for the differentiation of neoplastic from non-neoplastic colorectal polyps. PATIENTS AND METHODS: In total, 200 colorectal polyps from 99 patients were distributed in a 1 : 1 ratio in order to analyze the surface according to the pit pattern classification and vascular patterns by either magnifying chromoendoscopy or NBI magnification. Histologic analysis was performed on all lesions. RESULTS: Using the Kudo classification of mucosal patterns, NBI with magnification resulted in a sensitivity of 90.5 % and a specificity of 89.2 % for the differentiation of neoplastic vs. non-neoplastic lesions. This performance was comparable to magnifying chromoendoscopy with a sensitivity of 91.7 % and a specificity of 90 %, respectively. Using vascular patterns for differentiation, NBI with magnification correctly identified 93.7 % of neoplastic polyps and 89.2 % of non-neoplastic colorectal lesions, whereas magnifying chromoendoscopy had a specificity of 95 % but a sensitivity of only 66.7 %. CONCLUSION: NBI in combination with magnifying endoscopy is a promising tool for the differentiation of neoplastic from non-neoplastic colorectal polyps in vivo without the necessity of using dye. The detection of capillary vessels with NBI allows the evaluation of colorectal lesions based on the vascular patterns with high diagnostic accuracy. SN - 1438-8812 UR - https://www.unboundmedicine.com/medline/citation/18072061/Value_of_magnifying_chromoendoscopy_and_narrow_band_imaging__NBI__in_classifying_colorectal_polyps:_a_prospective_controlled_study_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-966781 DB - PRIME DP - Unbound Medicine ER -