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Inadequate chemoprophylaxis and the risk of malaria.
Aust Fam Physician. 2007 Dec; 36(12):1058-60.AF

Abstract

BACKGROUND

Malaria is an important disease for Australian travellers, particularly to Papua New Guinea. Travellers often seek health advice from their general practitioner before travel or if they develop illness after travel.

METHOD

A retrospective cohort investigation into malaria risk in a group of adult Australians that trekked the Kokoda trail in Papua New Guinea.

RESULTS

Six of 38 group members were diagnosed with malaria on return from Papua New Guinea. None of the 12 individuals who took chemoprophylaxis for the recommended period post-travel developed malaria compared to 4/24 travellers who terminated prophylaxis prematurely or 2/2 who took no chemoprophylaxis.

DISCUSSION

Chemoprophylaxis is effective if taken for the full recommended period following travel to a malaria endemic area; 4 weeks for doxycycline and mefloquine, and 7 days for atovaquone+proguanil. Malaria is a likely cause of illness in recently returned travellers from Papua New Guinea who develop a febrile illness.

Authors+Show Affiliations

CNC, Population Health, Hunter New England Health, Tamworth, New South Wales. peter.massey@hnehealth.nsw.gov.auNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18075636

Citation

Massey, Peter, et al. "Inadequate Chemoprophylaxis and the Risk of Malaria." Australian Family Physician, vol. 36, no. 12, 2007, pp. 1058-60.
Massey P, Durrheim DN, Speare R. Inadequate chemoprophylaxis and the risk of malaria. Aust Fam Physician. 2007;36(12):1058-60.
Massey, P., Durrheim, D. N., & Speare, R. (2007). Inadequate chemoprophylaxis and the risk of malaria. Australian Family Physician, 36(12), 1058-60.
Massey P, Durrheim DN, Speare R. Inadequate Chemoprophylaxis and the Risk of Malaria. Aust Fam Physician. 2007;36(12):1058-60. PubMed PMID: 18075636.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Inadequate chemoprophylaxis and the risk of malaria. AU - Massey,Peter, AU - Durrheim,David N, AU - Speare,Rick, PY - 2007/12/14/pubmed PY - 2008/1/18/medline PY - 2007/12/14/entrez SP - 1058 EP - 60 JF - Australian family physician JO - Aust Fam Physician VL - 36 IS - 12 N2 - BACKGROUND: Malaria is an important disease for Australian travellers, particularly to Papua New Guinea. Travellers often seek health advice from their general practitioner before travel or if they develop illness after travel. METHOD: A retrospective cohort investigation into malaria risk in a group of adult Australians that trekked the Kokoda trail in Papua New Guinea. RESULTS: Six of 38 group members were diagnosed with malaria on return from Papua New Guinea. None of the 12 individuals who took chemoprophylaxis for the recommended period post-travel developed malaria compared to 4/24 travellers who terminated prophylaxis prematurely or 2/2 who took no chemoprophylaxis. DISCUSSION: Chemoprophylaxis is effective if taken for the full recommended period following travel to a malaria endemic area; 4 weeks for doxycycline and mefloquine, and 7 days for atovaquone+proguanil. Malaria is a likely cause of illness in recently returned travellers from Papua New Guinea who develop a febrile illness. SN - 0300-8495 UR - https://www.unboundmedicine.com/medline/citation/18075636/Inadequate_chemoprophylaxis_and_the_risk_of_malaria_ L2 - http://www.racgp.org.au/afp/200712/21099 DB - PRIME DP - Unbound Medicine ER -