Tags

Type your tag names separated by a space and hit enter

Complicated grief and impaired sleep in patients with bipolar disorder.
Bipolar Disord. 2007 Dec; 9(8):913-7.BD

Abstract

OBJECTIVES

To examine the relationship of sleep disturbance with complicated grief (CG) in patients with bipolar disorder (BD).

METHODS

Adults with DSM-IV BD were asked if they ever experienced significant loss and, if so, completed the Inventory of Complicated Grief. Subjective sleep disturbance was assessed with the Pittsburgh Sleep Quality Index (PSQI). The association of CG with sleep disturbance was assessed in univariate t-tests, and in multivariate analyses controlling for the presence of anxiety disorder comorbidity and current bipolar recovery status.

RESULTS

Individuals with CG had significantly higher mean PSQI scores (10.9 versus 7.9, p = 0.003) than those without CG. Further, within the group of BD participants who had experienced a significant loss, those with CG had significantly poorer sleep (p = 0.01). CG remained significantly associated with greater sleep impairment after adjustment for comorbid anxiety disorder and bipolar mood state. This additive impairment in sleep with CG comorbidity was evident for four of the PSQI component scales: sleep quality, sleep duration, sleep efficiency and sleep disturbance.

CONCLUSIONS

Our data indicate a significant association of CG with poor sleep in individuals with BD. Disturbed sleep may be a mechanism by which CG increases the burden of illness in BD.

Authors+Show Affiliations

Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18076543

Citation

Maytal, Guy, et al. "Complicated Grief and Impaired Sleep in Patients With Bipolar Disorder." Bipolar Disorders, vol. 9, no. 8, 2007, pp. 913-7.
Maytal G, Zalta AK, Thompson E, et al. Complicated grief and impaired sleep in patients with bipolar disorder. Bipolar Disord. 2007;9(8):913-7.
Maytal, G., Zalta, A. K., Thompson, E., Chow, C. W., Perlman, C., Ostacher, M. J., Pollack, M. H., Shear, K., & Simon, N. M. (2007). Complicated grief and impaired sleep in patients with bipolar disorder. Bipolar Disorders, 9(8), 913-7.
Maytal G, et al. Complicated Grief and Impaired Sleep in Patients With Bipolar Disorder. Bipolar Disord. 2007;9(8):913-7. PubMed PMID: 18076543.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Complicated grief and impaired sleep in patients with bipolar disorder. AU - Maytal,Guy, AU - Zalta,Alyson K, AU - Thompson,Elizabeth, AU - Chow,Candice W, AU - Perlman,Carol, AU - Ostacher,Michael J, AU - Pollack,Mark H, AU - Shear,Katherine, AU - Simon,Naomi M, PY - 2007/12/14/pubmed PY - 2008/3/22/medline PY - 2007/12/14/entrez SP - 913 EP - 7 JF - Bipolar disorders JO - Bipolar Disord VL - 9 IS - 8 N2 - OBJECTIVES: To examine the relationship of sleep disturbance with complicated grief (CG) in patients with bipolar disorder (BD). METHODS: Adults with DSM-IV BD were asked if they ever experienced significant loss and, if so, completed the Inventory of Complicated Grief. Subjective sleep disturbance was assessed with the Pittsburgh Sleep Quality Index (PSQI). The association of CG with sleep disturbance was assessed in univariate t-tests, and in multivariate analyses controlling for the presence of anxiety disorder comorbidity and current bipolar recovery status. RESULTS: Individuals with CG had significantly higher mean PSQI scores (10.9 versus 7.9, p = 0.003) than those without CG. Further, within the group of BD participants who had experienced a significant loss, those with CG had significantly poorer sleep (p = 0.01). CG remained significantly associated with greater sleep impairment after adjustment for comorbid anxiety disorder and bipolar mood state. This additive impairment in sleep with CG comorbidity was evident for four of the PSQI component scales: sleep quality, sleep duration, sleep efficiency and sleep disturbance. CONCLUSIONS: Our data indicate a significant association of CG with poor sleep in individuals with BD. Disturbed sleep may be a mechanism by which CG increases the burden of illness in BD. SN - 1398-5647 UR - https://www.unboundmedicine.com/medline/citation/18076543/Complicated_grief_and_impaired_sleep_in_patients_with_bipolar_disorder_ L2 - https://doi.org/10.1111/j.1399-5618.2007.00446.x DB - PRIME DP - Unbound Medicine ER -