Tags

Type your tag names separated by a space and hit enter

Obstetric outcomes subsequent to intrauterine death in the first pregnancy.
BJOG. 2008 Jan; 115(2):269-74.BJOG

Abstract

OBJECTIVE

To compare obstetric outcomes in the pregnancy subsequent to intrauterine death with that following live birth in first pregnancy.

DESIGN

Retrospective cohort study.

SETTING

Grampian region of Scotland, UK.

POPULATION

All women who had their first and second deliveries in Grampian between 1976 and 2006.

METHODS

All women delivering for the first time between 1976 and 2002 had follow up until 2006 to study their next pregnancy. Those women who had an intrauterine death in their first pregnancy formed the exposed cohort, while those who had a live birth formed the unexposed cohort.

MAIN OUTCOME MEASURES

Maternal and neonatal outcomes in the second pregnancy, including pre-eclampsia, placental abruption, induction of labour, instrumental delivery, caesarean delivery, malpresentation, prematurity, low birthweight and stillbirth.

RESULTS

The exposed cohort (n = 364) was at increased risk of pre-eclampsia (OR 3.1, 95% CI 1.7-5.7); placental abruption (OR 9.4, 95% CI 4.5-19.7); induction of labour (OR 3.2, 95% CI 2.4-4.2); instrumental delivery (OR 2.0, 95% CI 1.4-3.0); elective (OR 3.1, 95% CI 2-4.8) and emergency caesarean deliveries (OR 2.1, 95% CI 1.5-3.0); and prematurity (OR 2.8, 95% CI 1.9-4.2), low birthweight (OR 2.8, 95% CI 1.7-4.5) and malpresentation (OR 2.8, 95% CI 2.0-3.9) of the infant as compared with the unexposed cohort (n = 33,715). The adjusted odds ratio for stillbirth was 1.2 and 95% CI 0.4-3.4.

CONCLUSION

While the majority of women with a previous stillbirth have a live birth in the subsequent pregnancy, they are a high-risk group with an increased incidence of adverse maternal and neonatal outcomes.

Authors+Show Affiliations

Department of Obstetrics and Gynaecology, Aberdeen Maternity Hospital, Aberdeen, UK.No affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

18081605

Citation

Black, M, et al. "Obstetric Outcomes Subsequent to Intrauterine Death in the First Pregnancy." BJOG : an International Journal of Obstetrics and Gynaecology, vol. 115, no. 2, 2008, pp. 269-74.
Black M, Shetty A, Bhattacharya S. Obstetric outcomes subsequent to intrauterine death in the first pregnancy. BJOG. 2008;115(2):269-74.
Black, M., Shetty, A., & Bhattacharya, S. (2008). Obstetric outcomes subsequent to intrauterine death in the first pregnancy. BJOG : an International Journal of Obstetrics and Gynaecology, 115(2), 269-74.
Black M, Shetty A, Bhattacharya S. Obstetric Outcomes Subsequent to Intrauterine Death in the First Pregnancy. BJOG. 2008;115(2):269-74. PubMed PMID: 18081605.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Obstetric outcomes subsequent to intrauterine death in the first pregnancy. AU - Black,M, AU - Shetty,A, AU - Bhattacharya,S, PY - 2007/12/18/pubmed PY - 2008/1/25/medline PY - 2007/12/18/entrez SP - 269 EP - 74 JF - BJOG : an international journal of obstetrics and gynaecology JO - BJOG VL - 115 IS - 2 N2 - OBJECTIVE: To compare obstetric outcomes in the pregnancy subsequent to intrauterine death with that following live birth in first pregnancy. DESIGN: Retrospective cohort study. SETTING: Grampian region of Scotland, UK. POPULATION: All women who had their first and second deliveries in Grampian between 1976 and 2006. METHODS: All women delivering for the first time between 1976 and 2002 had follow up until 2006 to study their next pregnancy. Those women who had an intrauterine death in their first pregnancy formed the exposed cohort, while those who had a live birth formed the unexposed cohort. MAIN OUTCOME MEASURES: Maternal and neonatal outcomes in the second pregnancy, including pre-eclampsia, placental abruption, induction of labour, instrumental delivery, caesarean delivery, malpresentation, prematurity, low birthweight and stillbirth. RESULTS: The exposed cohort (n = 364) was at increased risk of pre-eclampsia (OR 3.1, 95% CI 1.7-5.7); placental abruption (OR 9.4, 95% CI 4.5-19.7); induction of labour (OR 3.2, 95% CI 2.4-4.2); instrumental delivery (OR 2.0, 95% CI 1.4-3.0); elective (OR 3.1, 95% CI 2-4.8) and emergency caesarean deliveries (OR 2.1, 95% CI 1.5-3.0); and prematurity (OR 2.8, 95% CI 1.9-4.2), low birthweight (OR 2.8, 95% CI 1.7-4.5) and malpresentation (OR 2.8, 95% CI 2.0-3.9) of the infant as compared with the unexposed cohort (n = 33,715). The adjusted odds ratio for stillbirth was 1.2 and 95% CI 0.4-3.4. CONCLUSION: While the majority of women with a previous stillbirth have a live birth in the subsequent pregnancy, they are a high-risk group with an increased incidence of adverse maternal and neonatal outcomes. SN - 1471-0528 UR - https://www.unboundmedicine.com/medline/citation/18081605/Obstetric_outcomes_subsequent_to_intrauterine_death_in_the_first_pregnancy_ L2 - https://doi.org/10.1111/j.1471-0528.2007.01562.x DB - PRIME DP - Unbound Medicine ER -