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Two-year follow-up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens.
Acta Ophthalmol. 2008 Aug; 86(5):533-6.AO

Abstract

PURPOSE

To evaluate posterior capsule opacification (PCO) 2 years after cataract surgery following implantation of a hydrophilic or a hydrophobic single-piece acrylic intraocular lens (IOL) with a sharp edge.

METHODS

Phacoemulsification cataract surgery was performed in one eye of 120 patients with senile cataract in this prospective study. They were randomized to implantation of either a hydrophilic acrylic IOL (BL27; Bausch & Lomb, Rochester, NY, USA) or a hydrophobic acrylic IOL (AcrySof) SA60AT; Alcon Laboratories, Fort Worth, TX, USA). Two years after surgery, retroillumination images were obtained and PCO area and severity were evaluated using pocoman software. Best corrected visual acuity (VA) (both high-contrast [100%] and low-contrast [2.5%]), glare, laser flare and intraocular pressure were measured. Capsulotomy rates were recorded.

RESULTS

Patients implanted with the hydrophilic IOL had a greater percentage area and severity of PCO compared with patients with the hydrophobic IOL (p < 0.001). There was no difference in PCO between men and women in the hydrophilic group. However, in the hydrophobic group, women had significantly more PCO than men (p < 0.05). Patients with the hydrophobic acrylic IOL had better high- and low-contrast visual activity (VA) (p < 0.01) and less glare (p < 0.001) than those with a hydrophilic acrylic IOL. Of the patients with the hydrophilic IOL, 42% underwent capsulotomy, compared with 10% in the hydrophobic group (p < 0.001).

CONCLUSIONS

Two years after surgery, patients with the SA60AT hydrophobic acrylic IOL had less PCO and better high- and low-contrast VA than patients with the BL27 hydrophilic acrylic IOL.

Authors+Show Affiliations

Department of Clinical Neuroscience, St Erik's Eye Hospital, Karolinska Institute, Stockholm, Sweden. maria.kugelberg@sankterik.seNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18081899

Citation

Kugelberg, Maria, et al. "Two-year Follow-up of Posterior Capsule Opacification After Implantation of a Hydrophilic or Hydrophobic Acrylic Intraocular Lens." Acta Ophthalmologica, vol. 86, no. 5, 2008, pp. 533-6.
Kugelberg M, Wejde G, Jayaram H, et al. Two-year follow-up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens. Acta Ophthalmol. 2008;86(5):533-6.
Kugelberg, M., Wejde, G., Jayaram, H., & Zetterström, C. (2008). Two-year follow-up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens. Acta Ophthalmologica, 86(5), 533-6.
Kugelberg M, et al. Two-year Follow-up of Posterior Capsule Opacification After Implantation of a Hydrophilic or Hydrophobic Acrylic Intraocular Lens. Acta Ophthalmol. 2008;86(5):533-6. PubMed PMID: 18081899.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Two-year follow-up of posterior capsule opacification after implantation of a hydrophilic or hydrophobic acrylic intraocular lens. AU - Kugelberg,Maria, AU - Wejde,Gisela, AU - Jayaram,Hari, AU - Zetterström,Charlotta, Y1 - 2007/12/11/ PY - 2007/12/18/pubmed PY - 2009/2/5/medline PY - 2007/12/18/entrez SP - 533 EP - 6 JF - Acta ophthalmologica JO - Acta Ophthalmol VL - 86 IS - 5 N2 - PURPOSE: To evaluate posterior capsule opacification (PCO) 2 years after cataract surgery following implantation of a hydrophilic or a hydrophobic single-piece acrylic intraocular lens (IOL) with a sharp edge. METHODS: Phacoemulsification cataract surgery was performed in one eye of 120 patients with senile cataract in this prospective study. They were randomized to implantation of either a hydrophilic acrylic IOL (BL27; Bausch & Lomb, Rochester, NY, USA) or a hydrophobic acrylic IOL (AcrySof) SA60AT; Alcon Laboratories, Fort Worth, TX, USA). Two years after surgery, retroillumination images were obtained and PCO area and severity were evaluated using pocoman software. Best corrected visual acuity (VA) (both high-contrast [100%] and low-contrast [2.5%]), glare, laser flare and intraocular pressure were measured. Capsulotomy rates were recorded. RESULTS: Patients implanted with the hydrophilic IOL had a greater percentage area and severity of PCO compared with patients with the hydrophobic IOL (p < 0.001). There was no difference in PCO between men and women in the hydrophilic group. However, in the hydrophobic group, women had significantly more PCO than men (p < 0.05). Patients with the hydrophobic acrylic IOL had better high- and low-contrast visual activity (VA) (p < 0.01) and less glare (p < 0.001) than those with a hydrophilic acrylic IOL. Of the patients with the hydrophilic IOL, 42% underwent capsulotomy, compared with 10% in the hydrophobic group (p < 0.001). CONCLUSIONS: Two years after surgery, patients with the SA60AT hydrophobic acrylic IOL had less PCO and better high- and low-contrast VA than patients with the BL27 hydrophilic acrylic IOL. SN - 1755-3768 UR - https://www.unboundmedicine.com/medline/citation/18081899/Two_year_follow_up_of_posterior_capsule_opacification_after_implantation_of_a_hydrophilic_or_hydrophobic_acrylic_intraocular_lens_ L2 - https://doi.org/10.1111/j.1600-0420.2007.01094.x DB - PRIME DP - Unbound Medicine ER -