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Stimulant alcohol effects prime within session drinking behavior.
Psychopharmacology (Berl). 2008 Apr; 197(2):327-37.P

Abstract

RATIONALE

Individual differences in subjective alcohol effects have been shown to differ by risk status (e.g., family history of alcoholism) and to predict future risk for alcohol-related problems. Presumably, individual differences in both stimulant and sedative responses affect the rewarding value of drinking which, in turn, impacts future drinking behavior. Although plausible, this theoretical model is largely untested.

OBJECTIVES

The current study attempted to provide experimental evidence for the impact of subjective alcohol responses on within session drinking behavior.

MATERIALS AND METHODS

Using a placebo-controlled between-subjects alcohol administration paradigm, experiences and evaluations of stimulant and sedative alcohol effects (after a target dose of 0.06 g%) were assessed as predictors of ad-libitum consumption in the context of anticipatory stress.

RESULTS

Analyses indicated that an initial dose of alcohol increased experiences of both stimulation and sedation although stimulant effects were evaluated much more positively. In addition, stimulant effects after a priming dose predicted further consumption, whereas sedative effects did not.

CONCLUSIONS

At least among moderate to heavy drinking college students, stimulant alcohol effects are more reinforcing and predict within session drinking behavior under social stress. Increased attention should be given to stimulant alcohol effects as a risk factor for excessive consumption in this population. Incorporating information about stimulant alcohol effects in prevention and intervention programs may also be important if additional research supports the current results.

Authors+Show Affiliations

Department of Psychology, Yale University, 2 Hillhouse Ave, New Haven, CT 06520-8205, USA. william.corbin@yale.eduNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18084744

Citation

Corbin, William R., et al. "Stimulant Alcohol Effects Prime Within Session Drinking Behavior." Psychopharmacology, vol. 197, no. 2, 2008, pp. 327-37.
Corbin WR, Gearhardt A, Fromme K. Stimulant alcohol effects prime within session drinking behavior. Psychopharmacology (Berl). 2008;197(2):327-37.
Corbin, W. R., Gearhardt, A., & Fromme, K. (2008). Stimulant alcohol effects prime within session drinking behavior. Psychopharmacology, 197(2), 327-37.
Corbin WR, Gearhardt A, Fromme K. Stimulant Alcohol Effects Prime Within Session Drinking Behavior. Psychopharmacology (Berl). 2008;197(2):327-37. PubMed PMID: 18084744.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Stimulant alcohol effects prime within session drinking behavior. AU - Corbin,William R, AU - Gearhardt,Ashley, AU - Fromme,Kim, Y1 - 2007/12/15/ PY - 2007/07/04/received PY - 2007/11/27/accepted PY - 2007/12/18/pubmed PY - 2008/9/4/medline PY - 2007/12/18/entrez SP - 327 EP - 37 JF - Psychopharmacology JO - Psychopharmacology (Berl) VL - 197 IS - 2 N2 - RATIONALE: Individual differences in subjective alcohol effects have been shown to differ by risk status (e.g., family history of alcoholism) and to predict future risk for alcohol-related problems. Presumably, individual differences in both stimulant and sedative responses affect the rewarding value of drinking which, in turn, impacts future drinking behavior. Although plausible, this theoretical model is largely untested. OBJECTIVES: The current study attempted to provide experimental evidence for the impact of subjective alcohol responses on within session drinking behavior. MATERIALS AND METHODS: Using a placebo-controlled between-subjects alcohol administration paradigm, experiences and evaluations of stimulant and sedative alcohol effects (after a target dose of 0.06 g%) were assessed as predictors of ad-libitum consumption in the context of anticipatory stress. RESULTS: Analyses indicated that an initial dose of alcohol increased experiences of both stimulation and sedation although stimulant effects were evaluated much more positively. In addition, stimulant effects after a priming dose predicted further consumption, whereas sedative effects did not. CONCLUSIONS: At least among moderate to heavy drinking college students, stimulant alcohol effects are more reinforcing and predict within session drinking behavior under social stress. Increased attention should be given to stimulant alcohol effects as a risk factor for excessive consumption in this population. Incorporating information about stimulant alcohol effects in prevention and intervention programs may also be important if additional research supports the current results. SN - 0033-3158 UR - https://www.unboundmedicine.com/medline/citation/18084744/Stimulant_alcohol_effects_prime_within_session_drinking_behavior_ L2 - https://dx.doi.org/10.1007/s00213-007-1039-x DB - PRIME DP - Unbound Medicine ER -