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Green tea and coffee intake and risk of pancreatic cancer in a large-scale, population-based cohort study in Japan (JPHC study).
Eur J Cancer Prev. 2007 Dec; 16(6):542-8.EJ

Abstract

Pancreatic cancer is one of the most aggressive and treatment-refractory malignancies in humans. The most effective means of reducing pancreatic cancer mortality may be primary prevention. Although laboratory studies have demonstrated that green tea possesses anticancer activities, results from epidemiological studies have failed to show a consistent cancer-preventive effect. In addition, there is a lingering concern that coffee mighty increase the risk of pancreatic cancer although the most recent epidemiological studies showed no overall association between coffee and risk. Here, we examined the association between the drinking of green tea or coffee and the risk of pancreatic cancer in a large population-based cohort study in Japan (JPHC study). In total, 102 137 participants were followed for an average of 11 years through to the end of 2003. A total of 233 incident cases of pancreatic cancer were identified among 1 116 945 person-years of follow-up. Overall, the risk of pancreatic cancer was not associated with either green tea or coffee intake in our population, although a reduced risk was apparent among men who drank at least three cups of coffee per day compared with those who did not drink any or only rarely drank coffee. In conclusion, our findings support the idea that green tea or coffee consumption does not have a substantial impact on pancreatic cancer risk in general.

Authors+Show Affiliations

Epidemiology and Prevention Division, Research Center for Cancer Prevention and Screening, National Cancer Center, Tokyo, Japan.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18090127

Citation

Luo, Juhua, et al. "Green Tea and Coffee Intake and Risk of Pancreatic Cancer in a Large-scale, Population-based Cohort Study in Japan (JPHC Study)." European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), vol. 16, no. 6, 2007, pp. 542-8.
Luo J, Inoue M, Iwasaki M, et al. Green tea and coffee intake and risk of pancreatic cancer in a large-scale, population-based cohort study in Japan (JPHC study). Eur J Cancer Prev. 2007;16(6):542-8.
Luo, J., Inoue, M., Iwasaki, M., Sasazuki, S., Otani, T., Ye, W., & Tsugane, S. (2007). Green tea and coffee intake and risk of pancreatic cancer in a large-scale, population-based cohort study in Japan (JPHC study). European Journal of Cancer Prevention : the Official Journal of the European Cancer Prevention Organisation (ECP), 16(6), 542-8.
Luo J, et al. Green Tea and Coffee Intake and Risk of Pancreatic Cancer in a Large-scale, Population-based Cohort Study in Japan (JPHC Study). Eur J Cancer Prev. 2007;16(6):542-8. PubMed PMID: 18090127.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Green tea and coffee intake and risk of pancreatic cancer in a large-scale, population-based cohort study in Japan (JPHC study). AU - Luo,Juhua, AU - Inoue,Manami, AU - Iwasaki,Motoki, AU - Sasazuki,Shizuka, AU - Otani,Tetsuya, AU - Ye,Weimin, AU - Tsugane,Shoichiro, AU - ,, PY - 2007/12/20/pubmed PY - 2008/2/26/medline PY - 2007/12/20/entrez SP - 542 EP - 8 JF - European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) JO - Eur J Cancer Prev VL - 16 IS - 6 N2 - Pancreatic cancer is one of the most aggressive and treatment-refractory malignancies in humans. The most effective means of reducing pancreatic cancer mortality may be primary prevention. Although laboratory studies have demonstrated that green tea possesses anticancer activities, results from epidemiological studies have failed to show a consistent cancer-preventive effect. In addition, there is a lingering concern that coffee mighty increase the risk of pancreatic cancer although the most recent epidemiological studies showed no overall association between coffee and risk. Here, we examined the association between the drinking of green tea or coffee and the risk of pancreatic cancer in a large population-based cohort study in Japan (JPHC study). In total, 102 137 participants were followed for an average of 11 years through to the end of 2003. A total of 233 incident cases of pancreatic cancer were identified among 1 116 945 person-years of follow-up. Overall, the risk of pancreatic cancer was not associated with either green tea or coffee intake in our population, although a reduced risk was apparent among men who drank at least three cups of coffee per day compared with those who did not drink any or only rarely drank coffee. In conclusion, our findings support the idea that green tea or coffee consumption does not have a substantial impact on pancreatic cancer risk in general. SN - 0959-8278 UR - https://www.unboundmedicine.com/medline/citation/18090127/Green_tea_and_coffee_intake_and_risk_of_pancreatic_cancer_in_a_large_scale_population_based_cohort_study_in_Japan__JPHC_study__ L2 - https://doi.org/10.1097/CEJ.0b013e32809b4d30 DB - PRIME DP - Unbound Medicine ER -