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Upper limb function after intrathecal baclofen treatment in children with cerebral palsy.
J Pediatr Orthop. 2008 Jan-Feb; 28(1):91-6.JP

Abstract

BACKGROUND

The literature shows that intrathecal baclofen (ITB) treatment in patients with cerebral palsy (CP) is able to reduce spasticity. The purpose of this work is to evaluate the motor function of the upper limbs in patients with CP treated with ITB.

METHODS

A consecutive series of 20 patients with spastic CP (mean age at implant, 11.4 years) implanted with pumps in our center was studied. These patients were classified using the Gross Motor Function Classification System. The patients were followed up over a 12-month period for assessment of the upper limb function with the Melbourne Assessment of Unilateral Upper Limb Function scale.

RESULTS

The data show a reduction of upper limb spasticity in all 20 patients (P < 0.05). The Melbourne scale shows a statistically significant improvement of the total score (P < 0.05) and an improvement of the subskills of range of movement, target accuracy, and fluency. Twenty-five percent of patients showed a clinically significant improvement.

CONCLUSION

The subjects with CP of different degrees of severity had an improvement in the quality of the upper limb function and showed overall satisfaction with the results achieved. The study also shows the importance of evaluating the quality of upper limb function in children with CP treated with ITB therapy.

Authors+Show Affiliations

Department of Paediatric Orthopaedics, V Buzzi Children's Hospital, Milan, Italy. f.motta@icp.mi.itNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article

Language

eng

PubMed ID

18157052

Citation

Motta, Francesco, et al. "Upper Limb Function After Intrathecal Baclofen Treatment in Children With Cerebral Palsy." Journal of Pediatric Orthopedics, vol. 28, no. 1, 2008, pp. 91-6.
Motta F, Stignani C, Antonello CE. Upper limb function after intrathecal baclofen treatment in children with cerebral palsy. J Pediatr Orthop. 2008;28(1):91-6.
Motta, F., Stignani, C., & Antonello, C. E. (2008). Upper limb function after intrathecal baclofen treatment in children with cerebral palsy. Journal of Pediatric Orthopedics, 28(1), 91-6.
Motta F, Stignani C, Antonello CE. Upper Limb Function After Intrathecal Baclofen Treatment in Children With Cerebral Palsy. J Pediatr Orthop. 2008 Jan-Feb;28(1):91-6. PubMed PMID: 18157052.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Upper limb function after intrathecal baclofen treatment in children with cerebral palsy. AU - Motta,Francesco, AU - Stignani,Cecilia, AU - Antonello,Clara E, PY - 2007/12/25/pubmed PY - 2008/3/5/medline PY - 2007/12/25/entrez SP - 91 EP - 6 JF - Journal of pediatric orthopedics JO - J Pediatr Orthop VL - 28 IS - 1 N2 - BACKGROUND: The literature shows that intrathecal baclofen (ITB) treatment in patients with cerebral palsy (CP) is able to reduce spasticity. The purpose of this work is to evaluate the motor function of the upper limbs in patients with CP treated with ITB. METHODS: A consecutive series of 20 patients with spastic CP (mean age at implant, 11.4 years) implanted with pumps in our center was studied. These patients were classified using the Gross Motor Function Classification System. The patients were followed up over a 12-month period for assessment of the upper limb function with the Melbourne Assessment of Unilateral Upper Limb Function scale. RESULTS: The data show a reduction of upper limb spasticity in all 20 patients (P < 0.05). The Melbourne scale shows a statistically significant improvement of the total score (P < 0.05) and an improvement of the subskills of range of movement, target accuracy, and fluency. Twenty-five percent of patients showed a clinically significant improvement. CONCLUSION: The subjects with CP of different degrees of severity had an improvement in the quality of the upper limb function and showed overall satisfaction with the results achieved. The study also shows the importance of evaluating the quality of upper limb function in children with CP treated with ITB therapy. SN - 0271-6798 UR - https://www.unboundmedicine.com/medline/citation/18157052/Upper_limb_function_after_intrathecal_baclofen_treatment_in_children_with_cerebral_palsy_ L2 - http://Insights.ovid.com/pubmed?pmid=18157052 DB - PRIME DP - Unbound Medicine ER -