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Characterization of a dengue patient cohort in Recife, Brazil.
Am J Trop Med Hyg. 2007 Dec; 77(6):1128-34.AJ

Abstract

From 2004 to 2006, 658 patients with suspected dengue virus infections were enrolled in a clinical dengue cohort established in Recife, Pernambuco, located at the northeastern region of Brazil. A total of 2,364 blood samples were collected, and serum, plasma, and cells were cryopreserved. Among the suspected cases, 354 (54%) were confirmed as acute DENV-3 infection based on reverse transcription-polymerase chain reaction, virus isolation, and ELISA-IgM. According to WHO criteria, 29.4% of the positive acute cases were classified as dengue fever (DF) and 8.2% of the cases as dengue hemorrhagic fever (DHF), grade 1 or 2. The DHF cases represent 100% of those confirmed in Recife during the period of the study. The dengue cases that did not fulfill the definition of either DHF or DF were classified as DF complicated and accounted for 44.0% of the cases. All the acute cases were classified as either primary or secondary acute dengue virus infections. Secondary infection was predominant in patients with DF; however, there was no predominance of either primary or secondary infections in patients with DHF.

Authors+Show Affiliations

Laboratório de Virologia e Terapia Experimental do Centro de Pesquisas Aggeu Magalhães-CPqAM, Fiocruz, Recife, Pernambuco, Brazil.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18165535

Citation

Cordeiro, Marli Tenório, et al. "Characterization of a Dengue Patient Cohort in Recife, Brazil." The American Journal of Tropical Medicine and Hygiene, vol. 77, no. 6, 2007, pp. 1128-34.
Cordeiro MT, Silva AM, Brito CA, et al. Characterization of a dengue patient cohort in Recife, Brazil. Am J Trop Med Hyg. 2007;77(6):1128-34.
Cordeiro, M. T., Silva, A. M., Brito, C. A., Nascimento, E. J., Magalhães, M. C., Guimarães, G. F., Lucena-Silva, N., de Carvalho, E. M., & Marques, E. T. (2007). Characterization of a dengue patient cohort in Recife, Brazil. The American Journal of Tropical Medicine and Hygiene, 77(6), 1128-34.
Cordeiro MT, et al. Characterization of a Dengue Patient Cohort in Recife, Brazil. Am J Trop Med Hyg. 2007;77(6):1128-34. PubMed PMID: 18165535.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Characterization of a dengue patient cohort in Recife, Brazil. AU - Cordeiro,Marli Tenório, AU - Silva,Ana Maria, AU - Brito,Carlos A A, AU - Nascimento,Eduardo J M, AU - Magalhães,Maria Cecilia F, AU - Guimarães,Georgia F, AU - Lucena-Silva,Norma, AU - de Carvalho,Eduardo M Freese, AU - Marques,Ernesto T A,Jr PY - 2008/1/1/pubmed PY - 2008/2/15/medline PY - 2008/1/1/entrez SP - 1128 EP - 34 JF - The American journal of tropical medicine and hygiene JO - Am J Trop Med Hyg VL - 77 IS - 6 N2 - From 2004 to 2006, 658 patients with suspected dengue virus infections were enrolled in a clinical dengue cohort established in Recife, Pernambuco, located at the northeastern region of Brazil. A total of 2,364 blood samples were collected, and serum, plasma, and cells were cryopreserved. Among the suspected cases, 354 (54%) were confirmed as acute DENV-3 infection based on reverse transcription-polymerase chain reaction, virus isolation, and ELISA-IgM. According to WHO criteria, 29.4% of the positive acute cases were classified as dengue fever (DF) and 8.2% of the cases as dengue hemorrhagic fever (DHF), grade 1 or 2. The DHF cases represent 100% of those confirmed in Recife during the period of the study. The dengue cases that did not fulfill the definition of either DHF or DF were classified as DF complicated and accounted for 44.0% of the cases. All the acute cases were classified as either primary or secondary acute dengue virus infections. Secondary infection was predominant in patients with DF; however, there was no predominance of either primary or secondary infections in patients with DHF. SN - 0002-9637 UR - https://www.unboundmedicine.com/medline/citation/18165535/Characterization_of_a_dengue_patient_cohort_in_Recife_Brazil_ L2 - https://medlineplus.gov/dengue.html DB - PRIME DP - Unbound Medicine ER -