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A comparative study of the analgesic effect of patient-controlled morphine, pethidine, and tramadol for postoperative pain management after abdominal hysterectomy.
Anesth Analg. 2008 Jan; 106(1):309-12, table of contents.A&A

Abstract

We designed this prospective, randomized, double-blind study to compare the analgesic effectiveness and side effects of IV patient-controlled morphine, pethidine, and tramadol for postoperative pain management. One-hundred-twenty-six ASA physical status I or II patients undergoing abdominal hysterectomy were randomly allocated to receive IV-patient controlled morphine (M), pethidine (P), or tramadol (T) for postoperative analgesia. The cumulative analgesic consumption over 24 h was 25.7 +/- 9.5 mg for morphine, 266 +/- 90 mg for pethidine, and 320 +/- 10 mg for tramadol. The average supplementary fentanyl dose used was significantly higher in group T than in groups M and P (P < 0.05). In conclusion, morphine, pethidine, and tramadol resulted in equivalent pain scores and side effects, but tramadol group T required more rescue analgesic doses of fentanyl.

Authors+Show Affiliations

Department of Anaesthesiology, Cukurova University Faculty of Medicine, Adana, Turkey. unlugenc@cu.edu.trNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Randomized Controlled Trial

Language

eng

PubMed ID

18165596

Citation

Unlugenc, Hakki, et al. "A Comparative Study of the Analgesic Effect of Patient-controlled Morphine, Pethidine, and Tramadol for Postoperative Pain Management After Abdominal Hysterectomy." Anesthesia and Analgesia, vol. 106, no. 1, 2008, 309-12, table of contents.
Unlugenc H, Vardar MA, Tetiker S. A comparative study of the analgesic effect of patient-controlled morphine, pethidine, and tramadol for postoperative pain management after abdominal hysterectomy. Anesth Analg. 2008;106(1):309-12, table of contents.
Unlugenc, H., Vardar, M. A., & Tetiker, S. (2008). A comparative study of the analgesic effect of patient-controlled morphine, pethidine, and tramadol for postoperative pain management after abdominal hysterectomy. Anesthesia and Analgesia, 106(1), 309-12, table of contents. https://doi.org/10.1213/01.ane.0000287815.32869.2a
Unlugenc H, Vardar MA, Tetiker S. A Comparative Study of the Analgesic Effect of Patient-controlled Morphine, Pethidine, and Tramadol for Postoperative Pain Management After Abdominal Hysterectomy. Anesth Analg. 2008;106(1):309-12, table of contents. PubMed PMID: 18165596.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A comparative study of the analgesic effect of patient-controlled morphine, pethidine, and tramadol for postoperative pain management after abdominal hysterectomy. AU - Unlugenc,Hakki, AU - Vardar,Mehmet Ali, AU - Tetiker,Sibel, PY - 2008/1/1/pubmed PY - 2008/10/23/medline PY - 2008/1/1/entrez SP - 309-12, table of contents JF - Anesthesia and analgesia JO - Anesth. Analg. VL - 106 IS - 1 N2 - We designed this prospective, randomized, double-blind study to compare the analgesic effectiveness and side effects of IV patient-controlled morphine, pethidine, and tramadol for postoperative pain management. One-hundred-twenty-six ASA physical status I or II patients undergoing abdominal hysterectomy were randomly allocated to receive IV-patient controlled morphine (M), pethidine (P), or tramadol (T) for postoperative analgesia. The cumulative analgesic consumption over 24 h was 25.7 +/- 9.5 mg for morphine, 266 +/- 90 mg for pethidine, and 320 +/- 10 mg for tramadol. The average supplementary fentanyl dose used was significantly higher in group T than in groups M and P (P < 0.05). In conclusion, morphine, pethidine, and tramadol resulted in equivalent pain scores and side effects, but tramadol group T required more rescue analgesic doses of fentanyl. SN - 1526-7598 UR - https://www.unboundmedicine.com/medline/citation/18165596/A_comparative_study_of_the_analgesic_effect_of_patient_controlled_morphine_pethidine_and_tramadol_for_postoperative_pain_management_after_abdominal_hysterectomy_ L2 - http://dx.doi.org/10.1213/01.ane.0000287815.32869.2a DB - PRIME DP - Unbound Medicine ER -