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Alzheimer's disease - the ways of prevention.

Abstract

Several vascular and lifestyle related factors have been suggested to influence the development of dementia and Alzheimer's disease (AD), creating new prevention opportunities. This paper discusses current epidemiological evidence and new findings from the Finnish population based CAIDE study linking some of these factors to dementia/AD. Such findings provide an optimistic outlook especially for persons with genetic susceptibility; it may be possible to reduce the risk or postpone the onset of dementia by adopting healthy lifestyle options. The interplay of genes and environment in the aetiology of AD needs to be further investigated as well as the role of lifestyle and pharmacological interventions for the prevention of dementia.

Authors+Show Affiliations

,

Aging Research Center, Karolinska Institutet, Gavlegatan 16, S-113 30 Stockholm, Sweden. miia.kivipelto@ki.se

Source

MeSH

Age of Onset
Aged
Alzheimer Disease
Comorbidity
Dementia, Vascular
Diet
Exercise
Genetic Predisposition to Disease
Humans
Hypercholesterolemia
Hypertension
Life Style
Obesity
Risk Factors

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18165854

Citation

Kivipelto, M, and A Solomon. "Alzheimer's Disease - the Ways of Prevention." The Journal of Nutrition, Health & Aging, vol. 12, no. 1, 2008, 89S-94S.
Kivipelto M, Solomon A. Alzheimer's disease - the ways of prevention. J Nutr Health Aging. 2008;12(1):89S-94S.
Kivipelto, M., & Solomon, A. (2008). Alzheimer's disease - the ways of prevention. The Journal of Nutrition, Health & Aging, 12(1), 89S-94S.
Kivipelto M, Solomon A. Alzheimer's Disease - the Ways of Prevention. J Nutr Health Aging. 2008;12(1):89S-94S. PubMed PMID: 18165854.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Alzheimer's disease - the ways of prevention. AU - Kivipelto,M, AU - Solomon,A, PY - 2008/1/1/pubmed PY - 2008/3/29/medline PY - 2008/1/1/entrez SP - 89S EP - 94S JF - The journal of nutrition, health & aging JO - J Nutr Health Aging VL - 12 IS - 1 N2 - Several vascular and lifestyle related factors have been suggested to influence the development of dementia and Alzheimer's disease (AD), creating new prevention opportunities. This paper discusses current epidemiological evidence and new findings from the Finnish population based CAIDE study linking some of these factors to dementia/AD. Such findings provide an optimistic outlook especially for persons with genetic susceptibility; it may be possible to reduce the risk or postpone the onset of dementia by adopting healthy lifestyle options. The interplay of genes and environment in the aetiology of AD needs to be further investigated as well as the role of lifestyle and pharmacological interventions for the prevention of dementia. SN - 1279-7707 UR - https://www.unboundmedicine.com/medline/citation/18165854/Alzheimer's_disease___the_ways_of_prevention_ L2 - https://medlineplus.gov/exerciseandphysicalfitness.html DB - PRIME DP - Unbound Medicine ER -