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[Male infertility with severe oligospermatism and azoospermia treated by Bushen Shengjing Decoction combined with intracytoplasmic sperm injection].
Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Nov; 27(11):972-5.ZZ

Abstract

OBJECTIVE

To observe the pregnancy promoting effect of Bushen Shengjing Decoction (BSSJD) combined with intracytoplasmic sperm injection (ICSI) in treating male infertility with severe oligospermatism and azoospermia (SOA).

METHODS

ICSI were applied on 164 patients, among them, the 82 assigned to the TCM group were treated with additionally by BSSJD before injection for 2-3 months, and the other 82 assigned to the control group received ICSI alone. The density, motility, viability and deformity of sperm; semen level of reactive oxygen species (ROS); number of eggs retrieved, M II eggs and mean transplanted fetus; rates of fertilization, cleavage, available embryo and clinical pregnancy in the two groups were observed and compared.

RESULTS

Compared with those in the control group, the density, motility and viability of sperm were higher, the deformity rate and ROS level were lower in the TCM group respectively (P<0.05). Moreover, higher rates of fertilization and clinical pregnancy were also shown in the TCM group (P<0.05).

CONCLUSION

BSSJD has the effects of decreasing semen level of ROS and improving the quality of sperm. It is also helpful for the natural fertilization ability of patients with SOA and raise the viability of their sperm to increase the ovarian fertilization rate and clinical pregnancy rate in ICSI cycles.

Authors+Show Affiliations

Shanghai Institute of Planed Parenthood Research, Fudan University, Shanghai.No affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article
Research Support, Non-U.S. Gov't

Language

chi

PubMed ID

18173138

Citation

Zhang, Hui-qin, et al. "[Male Infertility With Severe Oligospermatism and Azoospermia Treated By Bushen Shengjing Decoction Combined With Intracytoplasmic Sperm Injection]." Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, vol. 27, no. 11, 2007, pp. 972-5.
Zhang HQ, Zhao HX, Zhang AJ. [Male infertility with severe oligospermatism and azoospermia treated by Bushen Shengjing Decoction combined with intracytoplasmic sperm injection]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007;27(11):972-5.
Zhang, H. Q., Zhao, H. X., & Zhang, A. J. (2007). [Male infertility with severe oligospermatism and azoospermia treated by Bushen Shengjing Decoction combined with intracytoplasmic sperm injection]. Zhongguo Zhong Xi Yi Jie He Za Zhi Zhongguo Zhongxiyi Jiehe Zazhi = Chinese Journal of Integrated Traditional and Western Medicine, 27(11), 972-5.
Zhang HQ, Zhao HX, Zhang AJ. [Male Infertility With Severe Oligospermatism and Azoospermia Treated By Bushen Shengjing Decoction Combined With Intracytoplasmic Sperm Injection]. Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007;27(11):972-5. PubMed PMID: 18173138.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Male infertility with severe oligospermatism and azoospermia treated by Bushen Shengjing Decoction combined with intracytoplasmic sperm injection]. AU - Zhang,Hui-qin, AU - Zhao,Hong-xin, AU - Zhang,Ai-jun, PY - 2008/1/5/pubmed PY - 2008/12/17/medline PY - 2008/1/5/entrez SP - 972 EP - 5 JF - Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine JO - Zhongguo Zhong Xi Yi Jie He Za Zhi VL - 27 IS - 11 N2 - OBJECTIVE: To observe the pregnancy promoting effect of Bushen Shengjing Decoction (BSSJD) combined with intracytoplasmic sperm injection (ICSI) in treating male infertility with severe oligospermatism and azoospermia (SOA). METHODS: ICSI were applied on 164 patients, among them, the 82 assigned to the TCM group were treated with additionally by BSSJD before injection for 2-3 months, and the other 82 assigned to the control group received ICSI alone. The density, motility, viability and deformity of sperm; semen level of reactive oxygen species (ROS); number of eggs retrieved, M II eggs and mean transplanted fetus; rates of fertilization, cleavage, available embryo and clinical pregnancy in the two groups were observed and compared. RESULTS: Compared with those in the control group, the density, motility and viability of sperm were higher, the deformity rate and ROS level were lower in the TCM group respectively (P<0.05). Moreover, higher rates of fertilization and clinical pregnancy were also shown in the TCM group (P<0.05). CONCLUSION: BSSJD has the effects of decreasing semen level of ROS and improving the quality of sperm. It is also helpful for the natural fertilization ability of patients with SOA and raise the viability of their sperm to increase the ovarian fertilization rate and clinical pregnancy rate in ICSI cycles. SN - 1003-5370 UR - https://www.unboundmedicine.com/medline/citation/18173138/[Male_infertility_with_severe_oligospermatism_and_azoospermia_treated_by_Bushen_Shengjing_Decoction_combined_with_intracytoplasmic_sperm_injection]_ L2 - http://www.diseaseinfosearch.org/result/9713 DB - PRIME DP - Unbound Medicine ER -