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A countywide outbreak of pertussis: initial transmission in a high school weight room with subsequent substantial impact on adolescents and adults.
Arch Pediatr Adolesc Med. 2008 Jan; 162(1):79-85.AP

Abstract

OBJECTIVE

To describe a large communitywide pertussis outbreak where aggressive diagnostic and treatment measures were used to control the outbreak.

DESIGN

Retrospective analysis, May 2003 through February 2004.

SETTING

Fond du Lac County, Wisconsin (population 98,882).

PARTICIPANTS

Health department personnel conducted case and contact investigations of suspected outbreak-associated illnesses using standard pertussis reporting forms and clinical evaluation and management protocols. Persons with compatible illness were tested for Bordetella pertussis using culture and for B pertussis DNA using polymerase chain reaction. Cases were classified using Council of State and Territorial Epidemiologists definitions.

INTERVENTIONS

Health alerts and aggressive testing and treatment of suspected cases of pertussis illness and contact prophylaxis in the community.

MAIN OUTCOME MEASURES

Incidences by age, onsets over time, and vaccine coverage in case patients.

RESULTS

We identified 261 pertussis cases among county residents; 149 (57%) were laboratory confirmed. Of the first 57 case patients, 47% reported using a particular high school weight room. Pertussis incidence was high in all age groups; 86% of case patients were 10 years or older. Among 156 case patients with reported vaccination histories, 84% had received 5 or more doses of pertussis-containing vaccine. Adults reported significantly more severe pertussis symptoms than adolescents.

CONCLUSIONS

Pertussis transmission among adolescents using a school weight room instigated a countywide outbreak with substantial incidence and morbidity among adolescents and adults. Aggressive testing and treatment in the outbreak response likely contributed to a sharp reduction in cases. This labor- and resource-intensive outbreak highlights potential benefits of pertussis booster vaccination among adolescent and adult populations.

Authors+Show Affiliations

Bureau of Communicable Diseases and Preparedness, Wisconsin Division of Public Health, Madison, Wisconsin 53702, USA.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18180417

Citation

Sotir, Mark J., et al. "A Countywide Outbreak of Pertussis: Initial Transmission in a High School Weight Room With Subsequent Substantial Impact On Adolescents and Adults." Archives of Pediatrics & Adolescent Medicine, vol. 162, no. 1, 2008, pp. 79-85.
Sotir MJ, Cappozzo DL, Warshauer DM, et al. A countywide outbreak of pertussis: initial transmission in a high school weight room with subsequent substantial impact on adolescents and adults. Arch Pediatr Adolesc Med. 2008;162(1):79-85.
Sotir, M. J., Cappozzo, D. L., Warshauer, D. M., Schmidt, C. E., Monson, T. A., Berg, J. L., Zastrow, J. A., Gabor, G. W., & Davis, J. P. (2008). A countywide outbreak of pertussis: initial transmission in a high school weight room with subsequent substantial impact on adolescents and adults. Archives of Pediatrics & Adolescent Medicine, 162(1), 79-85. https://doi.org/10.1001/archpediatrics.2007.7
Sotir MJ, et al. A Countywide Outbreak of Pertussis: Initial Transmission in a High School Weight Room With Subsequent Substantial Impact On Adolescents and Adults. Arch Pediatr Adolesc Med. 2008;162(1):79-85. PubMed PMID: 18180417.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - A countywide outbreak of pertussis: initial transmission in a high school weight room with subsequent substantial impact on adolescents and adults. AU - Sotir,Mark J, AU - Cappozzo,Dianne L, AU - Warshauer,David M, AU - Schmidt,Carol E, AU - Monson,Timothy A, AU - Berg,Jeffrey L, AU - Zastrow,Jean A, AU - Gabor,Gerald W, AU - Davis,Jeffrey P, PY - 2008/1/9/pubmed PY - 2008/2/22/medline PY - 2008/1/9/entrez SP - 79 EP - 85 JF - Archives of pediatrics & adolescent medicine JO - Arch Pediatr Adolesc Med VL - 162 IS - 1 N2 - OBJECTIVE: To describe a large communitywide pertussis outbreak where aggressive diagnostic and treatment measures were used to control the outbreak. DESIGN: Retrospective analysis, May 2003 through February 2004. SETTING: Fond du Lac County, Wisconsin (population 98,882). PARTICIPANTS: Health department personnel conducted case and contact investigations of suspected outbreak-associated illnesses using standard pertussis reporting forms and clinical evaluation and management protocols. Persons with compatible illness were tested for Bordetella pertussis using culture and for B pertussis DNA using polymerase chain reaction. Cases were classified using Council of State and Territorial Epidemiologists definitions. INTERVENTIONS: Health alerts and aggressive testing and treatment of suspected cases of pertussis illness and contact prophylaxis in the community. MAIN OUTCOME MEASURES: Incidences by age, onsets over time, and vaccine coverage in case patients. RESULTS: We identified 261 pertussis cases among county residents; 149 (57%) were laboratory confirmed. Of the first 57 case patients, 47% reported using a particular high school weight room. Pertussis incidence was high in all age groups; 86% of case patients were 10 years or older. Among 156 case patients with reported vaccination histories, 84% had received 5 or more doses of pertussis-containing vaccine. Adults reported significantly more severe pertussis symptoms than adolescents. CONCLUSIONS: Pertussis transmission among adolescents using a school weight room instigated a countywide outbreak with substantial incidence and morbidity among adolescents and adults. Aggressive testing and treatment in the outbreak response likely contributed to a sharp reduction in cases. This labor- and resource-intensive outbreak highlights potential benefits of pertussis booster vaccination among adolescent and adult populations. SN - 1538-3628 UR - https://www.unboundmedicine.com/medline/citation/18180417/A_countywide_outbreak_of_pertussis:_initial_transmission_in_a_high_school_weight_room_with_subsequent_substantial_impact_on_adolescents_and_adults_ L2 - https://jamanetwork.com/journals/jamapediatrics/fullarticle/10.1001/archpediatrics.2007.7 DB - PRIME DP - Unbound Medicine ER -