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Seroprevalence of IgG antibodies against Bordetella pertussis in healthy individuals aged 4-24 years in Turkey.
Clin Microbiol Infect. 2008 Apr; 14(4):388-90.CM

Abstract

The distribution of IgG antibodies to Bordetella pertussis was investigated in serum samples from 550 subjects, aged 4-24 years, to determine the optimal age for booster immunisation. Levels of antibody to B. pertussis antigens were determined using an ELISA that measures a mixture of pertussis toxin, filamentous haemagglutinin and lipopolysaccharide. Geometric mean titres of anti-pertussis antibodies in subjects aged 4-6 years were significantly lower than those in other age groups, which reflects waning immunity following vaccination. High positive titres in older children and adolescents suggested acquired B. pertussis infection, and booster doses at the ages of 7 and 15 years are therefore suggested.

Authors+Show Affiliations

Department of Family Practice, Ankara Numune Research and Education Hospital, Ankara, Turkey.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18190581

Citation

Cevik, M, et al. "Seroprevalence of IgG Antibodies Against Bordetella Pertussis in Healthy Individuals Aged 4-24 Years in Turkey." Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, vol. 14, no. 4, 2008, pp. 388-90.
Cevik M, Beyazova U, Aral AL, et al. Seroprevalence of IgG antibodies against Bordetella pertussis in healthy individuals aged 4-24 years in Turkey. Clin Microbiol Infect. 2008;14(4):388-90.
Cevik, M., Beyazova, U., Aral, A. L., Duyan Camurdan, A., Ozkan, S., Sahin, F., & Aybay, C. (2008). Seroprevalence of IgG antibodies against Bordetella pertussis in healthy individuals aged 4-24 years in Turkey. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases, 14(4), 388-90. https://doi.org/10.1111/j.1469-0691.2007.01926.x
Cevik M, et al. Seroprevalence of IgG Antibodies Against Bordetella Pertussis in Healthy Individuals Aged 4-24 Years in Turkey. Clin Microbiol Infect. 2008;14(4):388-90. PubMed PMID: 18190581.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Seroprevalence of IgG antibodies against Bordetella pertussis in healthy individuals aged 4-24 years in Turkey. AU - Cevik,M, AU - Beyazova,U, AU - Aral,A L, AU - Duyan Camurdan,A, AU - Ozkan,S, AU - Sahin,F, AU - Aybay,C, Y1 - 2008/01/07/ PY - 2008/1/15/pubmed PY - 2008/6/19/medline PY - 2008/1/15/entrez SP - 388 EP - 90 JF - Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases JO - Clin Microbiol Infect VL - 14 IS - 4 N2 - The distribution of IgG antibodies to Bordetella pertussis was investigated in serum samples from 550 subjects, aged 4-24 years, to determine the optimal age for booster immunisation. Levels of antibody to B. pertussis antigens were determined using an ELISA that measures a mixture of pertussis toxin, filamentous haemagglutinin and lipopolysaccharide. Geometric mean titres of anti-pertussis antibodies in subjects aged 4-6 years were significantly lower than those in other age groups, which reflects waning immunity following vaccination. High positive titres in older children and adolescents suggested acquired B. pertussis infection, and booster doses at the ages of 7 and 15 years are therefore suggested. SN - 1198-743X UR - https://www.unboundmedicine.com/medline/citation/18190581/Seroprevalence_of_IgG_antibodies_against_Bordetella_pertussis_in_healthy_individuals_aged_4_24_years_in_Turkey_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1198-743X(14)62814-7 DB - PRIME DP - Unbound Medicine ER -