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[Signal transduction mechanisms of steroid hormone receptors].
Nihon Rinsho. 2008 Jan; 66(1):47-54.NR

Abstract

The multiple physiological effects of steroid hormones are mediated by the cognate nuclear receptors through transcriptional regulation of target gene expression. Recently, post-transcriptional modifications of steroid receptors and cross-talk between steroid hormone signaling with other signaling pathways have been found to play a pivotal role in cell- and gene-specific transcriptional regulation. This is a brief overview on the role of interaction with different transcriptional factors and specific post-translational modifications (phosphorylation, acetylation and ubiquitination) of nuclear receptors in defining the physiological outcome of steroid hormone action.

Authors+Show Affiliations

Institute of Molecular and Cellular Biosciences, University of Tokyo.No affiliation info available

Pub Type(s)

English Abstract
Journal Article
Review

Language

jpn

PubMed ID

18193543

Citation

Takeyama, Ken-ichi, and Shigeaki Kato. "[Signal Transduction Mechanisms of Steroid Hormone Receptors]." Nihon Rinsho. Japanese Journal of Clinical Medicine, vol. 66, no. 1, 2008, pp. 47-54.
Takeyama K, Kato S. [Signal transduction mechanisms of steroid hormone receptors]. Nihon Rinsho. 2008;66(1):47-54.
Takeyama, K., & Kato, S. (2008). [Signal transduction mechanisms of steroid hormone receptors]. Nihon Rinsho. Japanese Journal of Clinical Medicine, 66(1), 47-54.
Takeyama K, Kato S. [Signal Transduction Mechanisms of Steroid Hormone Receptors]. Nihon Rinsho. 2008;66(1):47-54. PubMed PMID: 18193543.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Signal transduction mechanisms of steroid hormone receptors]. AU - Takeyama,Ken-ichi, AU - Kato,Shigeaki, PY - 2008/1/15/pubmed PY - 2008/3/7/medline PY - 2008/1/15/entrez SP - 47 EP - 54 JF - Nihon rinsho. Japanese journal of clinical medicine JO - Nihon Rinsho VL - 66 IS - 1 N2 - The multiple physiological effects of steroid hormones are mediated by the cognate nuclear receptors through transcriptional regulation of target gene expression. Recently, post-transcriptional modifications of steroid receptors and cross-talk between steroid hormone signaling with other signaling pathways have been found to play a pivotal role in cell- and gene-specific transcriptional regulation. This is a brief overview on the role of interaction with different transcriptional factors and specific post-translational modifications (phosphorylation, acetylation and ubiquitination) of nuclear receptors in defining the physiological outcome of steroid hormone action. SN - 0047-1852 UR - https://www.unboundmedicine.com/medline/citation/18193543/[Signal_transduction_mechanisms_of_steroid_hormone_receptors]_ DB - PRIME DP - Unbound Medicine ER -
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