Tags

Type your tag names separated by a space and hit enter

Magnetic resonance imaging findings and clinical associations in 52 dogs with suspected ischemic myelopathy.
J Vet Intern Med. 2007 Nov-Dec; 21(6):1290-8.JV

Abstract

BACKGROUND

The magnetic resonance imaging (MRI) features of ischemic myelopathy have been described in the human literature and in a small number of cases in the veterinary literature.

HYPOTHESIS

The aims of this study were to identify associations among MRI findings, timing of imaging, and presenting neurologic deficits in a large series of dogs with a presumptive diagnosis of ischemic myelopathy.

ANIMALS AND METHODS

The medical records and MR images of dogs with a presumptive diagnosis of ischemic myelopathy (2000-2006) were reviewed retrospectively. Inclusion criteria were acute onset of nonprogressive and nonpainful myelopathy, 1.5-tesla MRI of the spine performed within 7 days of onset, and complete medical records and follow-up information. Presumptive diagnosis was based on history, as well as clinical, MRI, and cerebrospinal fluid (CSF) findings. The extent of the lesion on MRI was assessed as the following: (1) the ratio between the length of the hyperintense area on sagittal T2-weighted images and the length of C6 or L2 vertebral body, and (2) the maximal cross-sectional area of the hyperintense area on transverse T2-weighted images as a percentage of cross-sectional area of the spinal cord.

RESULTS

Fifty-two dogs met the inclusion criteria. MRI findings were abnormal in 41 dogs and normal in 11 dogs. The presence of MRI abnormalities was not significantly associated with the timing of imaging (P = .3) but was associated with ambulatory status on presentation (P = .04). Severity of signs on presentation was associated with extent of the lesion on MRI (P = .02).

CONCLUSION AND CLINICAL IMPORTANCE

The severity of signs on presentation is associated with the presence and the extent of the lesion on MRI.

Authors+Show Affiliations

Neurology/Neurosurgery Unit, Centre for Small Animal Studies, Animal Health Trust, Lanwades Park, Kentford, Newmarket, Suffolk CB8 7UU, UK. luisa.derisio@aht.org.ukNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18196739

Citation

De Risio, Luisa, et al. "Magnetic Resonance Imaging Findings and Clinical Associations in 52 Dogs With Suspected Ischemic Myelopathy." Journal of Veterinary Internal Medicine, vol. 21, no. 6, 2007, pp. 1290-8.
De Risio L, Adams V, Dennis R, et al. Magnetic resonance imaging findings and clinical associations in 52 dogs with suspected ischemic myelopathy. J Vet Intern Med. 2007;21(6):1290-8.
De Risio, L., Adams, V., Dennis, R., McConnell, F., & Platt, S. (2007). Magnetic resonance imaging findings and clinical associations in 52 dogs with suspected ischemic myelopathy. Journal of Veterinary Internal Medicine, 21(6), 1290-8.
De Risio L, et al. Magnetic Resonance Imaging Findings and Clinical Associations in 52 Dogs With Suspected Ischemic Myelopathy. J Vet Intern Med. 2007 Nov-Dec;21(6):1290-8. PubMed PMID: 18196739.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Magnetic resonance imaging findings and clinical associations in 52 dogs with suspected ischemic myelopathy. AU - De Risio,Luisa, AU - Adams,Vicki, AU - Dennis,Ruth, AU - McConnell,Fraser, AU - Platt,Simon, PY - 2008/1/17/pubmed PY - 2008/2/15/medline PY - 2008/1/17/entrez SP - 1290 EP - 8 JF - Journal of veterinary internal medicine JO - J Vet Intern Med VL - 21 IS - 6 N2 - BACKGROUND: The magnetic resonance imaging (MRI) features of ischemic myelopathy have been described in the human literature and in a small number of cases in the veterinary literature. HYPOTHESIS: The aims of this study were to identify associations among MRI findings, timing of imaging, and presenting neurologic deficits in a large series of dogs with a presumptive diagnosis of ischemic myelopathy. ANIMALS AND METHODS: The medical records and MR images of dogs with a presumptive diagnosis of ischemic myelopathy (2000-2006) were reviewed retrospectively. Inclusion criteria were acute onset of nonprogressive and nonpainful myelopathy, 1.5-tesla MRI of the spine performed within 7 days of onset, and complete medical records and follow-up information. Presumptive diagnosis was based on history, as well as clinical, MRI, and cerebrospinal fluid (CSF) findings. The extent of the lesion on MRI was assessed as the following: (1) the ratio between the length of the hyperintense area on sagittal T2-weighted images and the length of C6 or L2 vertebral body, and (2) the maximal cross-sectional area of the hyperintense area on transverse T2-weighted images as a percentage of cross-sectional area of the spinal cord. RESULTS: Fifty-two dogs met the inclusion criteria. MRI findings were abnormal in 41 dogs and normal in 11 dogs. The presence of MRI abnormalities was not significantly associated with the timing of imaging (P = .3) but was associated with ambulatory status on presentation (P = .04). Severity of signs on presentation was associated with extent of the lesion on MRI (P = .02). CONCLUSION AND CLINICAL IMPORTANCE: The severity of signs on presentation is associated with the presence and the extent of the lesion on MRI. SN - 0891-6640 UR - https://www.unboundmedicine.com/medline/citation/18196739/Magnetic_resonance_imaging_findings_and_clinical_associations_in_52_dogs_with_suspected_ischemic_myelopathy_ L2 - https://onlinelibrary.wiley.com/resolve/openurl?genre=article&sid=nlm:pubmed&issn=0891-6640&date=2007&volume=21&issue=6&spage=1290 DB - PRIME DP - Unbound Medicine ER -