Tags

Type your tag names separated by a space and hit enter

New developments in the epidemiology and clinical spectrum of rhinovirus infections.
Curr Opin Pediatr. 2008 Feb; 20(1):67-71.CO

Abstract

PURPOSE OF REVIEW

The purpose of this review is to summarize the recent changes in our understanding of the epidemiology and clinical manifestations of rhinovirus infection that have occurred as a result of the improved diagnostic sensitivity provided by the reverse transcriptase PCR assays.

RECENT FINDINGS

Rhinovirus infection is now recognized as an important cause of acute exacerbations of asthma in school-aged children. Along with other respiratory viruses, rhinovirus infection is also a cause of exacerbations of cystic fibrosis. There is evidence that rhinovirus can infect the lower airways and may be associated with bronchiolitis and pneumonia in immunocompetent children and with lower respiratory tract disease in the immunocompromised host.

SUMMARY

The use of nucleic acid hybridization-based assays has expanded our understanding of the spectrum of clinical illness that is associated with rhinovirus infection. The prevalence of rhinovirus infection in children is high and presents a risk for coincidental detection of rhinovirus in the face of other infectious syndromes. The detection of rhinovirus from patients with new or unusual clinical syndromes does not permit the assumption that rhinovirus is playing a causal role in the illness.

Authors+Show Affiliations

Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA.No affiliation info available

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18197042

Citation

Brownlee, Joshua W., and Ronald B. Turner. "New Developments in the Epidemiology and Clinical Spectrum of Rhinovirus Infections." Current Opinion in Pediatrics, vol. 20, no. 1, 2008, pp. 67-71.
Brownlee JW, Turner RB. New developments in the epidemiology and clinical spectrum of rhinovirus infections. Curr Opin Pediatr. 2008;20(1):67-71.
Brownlee, J. W., & Turner, R. B. (2008). New developments in the epidemiology and clinical spectrum of rhinovirus infections. Current Opinion in Pediatrics, 20(1), 67-71. https://doi.org/10.1097/MOP.0b013e3282f41cb6
Brownlee JW, Turner RB. New Developments in the Epidemiology and Clinical Spectrum of Rhinovirus Infections. Curr Opin Pediatr. 2008;20(1):67-71. PubMed PMID: 18197042.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - New developments in the epidemiology and clinical spectrum of rhinovirus infections. AU - Brownlee,Joshua W, AU - Turner,Ronald B, PY - 2008/1/17/pubmed PY - 2008/4/11/medline PY - 2008/1/17/entrez SP - 67 EP - 71 JF - Current opinion in pediatrics JO - Curr Opin Pediatr VL - 20 IS - 1 N2 - PURPOSE OF REVIEW: The purpose of this review is to summarize the recent changes in our understanding of the epidemiology and clinical manifestations of rhinovirus infection that have occurred as a result of the improved diagnostic sensitivity provided by the reverse transcriptase PCR assays. RECENT FINDINGS: Rhinovirus infection is now recognized as an important cause of acute exacerbations of asthma in school-aged children. Along with other respiratory viruses, rhinovirus infection is also a cause of exacerbations of cystic fibrosis. There is evidence that rhinovirus can infect the lower airways and may be associated with bronchiolitis and pneumonia in immunocompetent children and with lower respiratory tract disease in the immunocompromised host. SUMMARY: The use of nucleic acid hybridization-based assays has expanded our understanding of the spectrum of clinical illness that is associated with rhinovirus infection. The prevalence of rhinovirus infection in children is high and presents a risk for coincidental detection of rhinovirus in the face of other infectious syndromes. The detection of rhinovirus from patients with new or unusual clinical syndromes does not permit the assumption that rhinovirus is playing a causal role in the illness. SN - 1040-8703 UR - https://www.unboundmedicine.com/medline/citation/18197042/New_developments_in_the_epidemiology_and_clinical_spectrum_of_rhinovirus_infections_ L2 - https://doi.org/10.1097/MOP.0b013e3282f41cb6 DB - PRIME DP - Unbound Medicine ER -