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[Overall and therapy specific mortality of patients hospitalized for acute myocardial infarction in Zagreb University Hospital Centre].
Lijec Vjesn. 2007 Aug-Sep; 129(8-9):260-4.LV

Abstract

In Coronary Care Unit and Intensive Care Unit, Zagreb University Hospital Centre, 403 patients were hospitalized for acute myocardial infarction (AMI) in the year 2005. Majority (288) patients presented with ST-segment elevation myocardial infarction (STEMI) and 115 patients with acute myocardial infarction without ST-segment elevation (NSTEMI). In-hospital mortality of STEMI patients was 13.9% vs. 9.6% of NSTEMI group of patients. In STEMI group 202 patients underwent urgent percutaneous coronary intervention (PCI), and 86 patients in STEMI group received conservative therapy. In-hospital mortality of patients treated with primary PCI was 5.9% vs. 29.1% in the group treated conservatively. The main reason for conservative therapy was late presentation to the hospital (> 12 hours from the beginning of symptoms). Only 11 high-risk patients in NSTEMI group underwent primary PCI and 99 NSTEMI patients received conservative therapy (in-hospital mortality 10.1%). We performed totally 218 urgent PCI interventions in both groups with low in-hospital mortality of 6.1% in comparison with high mortality in conservatively treated groups of patients. The mortality in PCI group was strongly connected with unsuccessful intervention and late reperfusion. Total ischemic time (6 hours and 5 minutes), and time from hospital presentation to reperfusion -"door to balloon time" (1 hour and 25 minutes) are longer that in similar patients series, and need to be improved. Transportation time (1 hour and 40 minutes) is acceptable. In conclusion, high percentage (70.1%) of STEMI and NSTEMI patients underwent primary PCI in our institution with low perioperative mortality. This group of patients had superior in-hospital mortality when compared with conservatively treated group of patients. There is still unacceptably high percentage of patients with AMI, who came into the hospital too late for any reperfusion therapy.

Authors+Show Affiliations

Klinika za bolesti srca i krvnih zila, KBC Zagreb maja.strozzi@zg.htnet.hrNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

English Abstract
Journal Article

Language

hrv

PubMed ID

18198624

Citation

Strozzi, Maja, et al. "[Overall and Therapy Specific Mortality of Patients Hospitalized for Acute Myocardial Infarction in Zagreb University Hospital Centre]." Lijecnicki Vjesnik, vol. 129, no. 8-9, 2007, pp. 260-4.
Strozzi M, Bulum J, Ernst A, et al. [Overall and therapy specific mortality of patients hospitalized for acute myocardial infarction in Zagreb University Hospital Centre]. Lijec Vjesn. 2007;129(8-9):260-4.
Strozzi, M., Bulum, J., Ernst, A., Margetić, E., Skorak, I., Putarek, K., & Gornik, I. (2007). [Overall and therapy specific mortality of patients hospitalized for acute myocardial infarction in Zagreb University Hospital Centre]. Lijecnicki Vjesnik, 129(8-9), 260-4.
Strozzi M, et al. [Overall and Therapy Specific Mortality of Patients Hospitalized for Acute Myocardial Infarction in Zagreb University Hospital Centre]. Lijec Vjesn. 2007 Aug-Sep;129(8-9):260-4. PubMed PMID: 18198624.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Overall and therapy specific mortality of patients hospitalized for acute myocardial infarction in Zagreb University Hospital Centre]. AU - Strozzi,Maja, AU - Bulum,Josko, AU - Ernst,Aleksander, AU - Margetić,Eduard, AU - Skorak,Ivan, AU - Putarek,Kresimir, AU - Gornik,Ivan, PY - 2008/1/18/pubmed PY - 2008/4/2/medline PY - 2008/1/18/entrez SP - 260 EP - 4 JF - Lijecnicki vjesnik JO - Lijec Vjesn VL - 129 IS - 8-9 N2 - In Coronary Care Unit and Intensive Care Unit, Zagreb University Hospital Centre, 403 patients were hospitalized for acute myocardial infarction (AMI) in the year 2005. Majority (288) patients presented with ST-segment elevation myocardial infarction (STEMI) and 115 patients with acute myocardial infarction without ST-segment elevation (NSTEMI). In-hospital mortality of STEMI patients was 13.9% vs. 9.6% of NSTEMI group of patients. In STEMI group 202 patients underwent urgent percutaneous coronary intervention (PCI), and 86 patients in STEMI group received conservative therapy. In-hospital mortality of patients treated with primary PCI was 5.9% vs. 29.1% in the group treated conservatively. The main reason for conservative therapy was late presentation to the hospital (> 12 hours from the beginning of symptoms). Only 11 high-risk patients in NSTEMI group underwent primary PCI and 99 NSTEMI patients received conservative therapy (in-hospital mortality 10.1%). We performed totally 218 urgent PCI interventions in both groups with low in-hospital mortality of 6.1% in comparison with high mortality in conservatively treated groups of patients. The mortality in PCI group was strongly connected with unsuccessful intervention and late reperfusion. Total ischemic time (6 hours and 5 minutes), and time from hospital presentation to reperfusion -"door to balloon time" (1 hour and 25 minutes) are longer that in similar patients series, and need to be improved. Transportation time (1 hour and 40 minutes) is acceptable. In conclusion, high percentage (70.1%) of STEMI and NSTEMI patients underwent primary PCI in our institution with low perioperative mortality. This group of patients had superior in-hospital mortality when compared with conservatively treated group of patients. There is still unacceptably high percentage of patients with AMI, who came into the hospital too late for any reperfusion therapy. SN - 0024-3477 UR - https://www.unboundmedicine.com/medline/citation/18198624/[Overall_and_therapy_specific_mortality_of_patients_hospitalized_for_acute_myocardial_infarction_in_Zagreb_University_Hospital_Centre]_ L2 - https://medlineplus.gov/heartattack.html DB - PRIME DP - Unbound Medicine ER -