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Psychiatric comorbidity in young cocaine users: induced versus independent disorders.
Addiction. 2008 Feb; 103(2):284-93.A

Abstract

AIMS

To examine the psychiatric status of young cocaine users using a validated instrument for the evaluation of psychiatric comorbidity, emphasizing the distinction between independent and induced psychiatric conditions.

DESIGN

Cross-sectional study.

SETTING

Barcelona, Spain.

PARTICIPANTS

A cohort of 139 young (18-30 years) adult current regular cocaine users.

MEASUREMENTS

The Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV, which produces diagnoses according to DSM-IV criteria, including Axis II antisocial and borderline personality disorders).

FINDINGS

Nearly 42.5% of the subjects presented psychiatric comorbidity. The most common Axis I diagnoses were mood disorders (26.6%) and anxiety disorders (13%). Increasing age, having ever received treatment for drug use and freebase cocaine use were associated with substance-induced disorders diagnoses relative to primary Axis I disorders.

CONCLUSIONS

This study has shown a relatively high prevalence of psychiatric comorbidity in cocaine users recruited in non-clinical settings. Future studies examining potential differential factors associated with primary versus substance-induced disorders are necessary to optimize the implementation of more suitable approaching programmes for young regular cocaine users.

Links

Publisher Full Text (DOI)

Authors+Show Affiliations

Herrero MJ
Health Services Research Unit (IMIM-Hospital del Mar), Barcelona, Spain.
Domingo-Salvany A
No affiliation info available
Torrens M
No affiliation info available
Brugal MT
No affiliation info available
ITINERE Investigators
No affiliation info available

MeSH

AdolescentAdultCocaine-Related DisordersCrack CocaineDopamine Uptake InhibitorsEpidemiologic MethodsFemaleHumansMaleMental DisordersPsychiatric Status Rating ScalesSpain

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18199307

Citation

Herrero, M Jesús, et al. "Psychiatric Comorbidity in Young Cocaine Users: Induced Versus Independent Disorders." Addiction (Abingdon, England), vol. 103, no. 2, 2008, pp. 284-93.
Herrero MJ, Domingo-Salvany A, Torrens M, et al. Psychiatric comorbidity in young cocaine users: induced versus independent disorders. Addiction. 2008;103(2):284-93.
Herrero, M. J., Domingo-Salvany, A., Torrens, M., & Brugal, M. T. (2008). Psychiatric comorbidity in young cocaine users: induced versus independent disorders. Addiction (Abingdon, England), 103(2), 284-93. https://doi.org/10.1111/j.1360-0443.2007.02076.x
Herrero MJ, et al. Psychiatric Comorbidity in Young Cocaine Users: Induced Versus Independent Disorders. Addiction. 2008;103(2):284-93. PubMed PMID: 18199307.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Psychiatric comorbidity in young cocaine users: induced versus independent disorders. AU - Herrero,M Jesús, AU - Domingo-Salvany,Antonia, AU - Torrens,Marta, AU - Brugal,M Teresa, AU - ,, PY - 2008/1/18/pubmed PY - 2008/6/11/medline PY - 2008/1/18/entrez SP - 284 EP - 93 JF - Addiction (Abingdon, England) JO - Addiction VL - 103 IS - 2 N2 - AIMS: To examine the psychiatric status of young cocaine users using a validated instrument for the evaluation of psychiatric comorbidity, emphasizing the distinction between independent and induced psychiatric conditions. DESIGN: Cross-sectional study. SETTING: Barcelona, Spain. PARTICIPANTS: A cohort of 139 young (18-30 years) adult current regular cocaine users. MEASUREMENTS: The Psychiatric Research Interview for Substance and Mental Disorders (PRISM-IV, which produces diagnoses according to DSM-IV criteria, including Axis II antisocial and borderline personality disorders). FINDINGS: Nearly 42.5% of the subjects presented psychiatric comorbidity. The most common Axis I diagnoses were mood disorders (26.6%) and anxiety disorders (13%). Increasing age, having ever received treatment for drug use and freebase cocaine use were associated with substance-induced disorders diagnoses relative to primary Axis I disorders. CONCLUSIONS: This study has shown a relatively high prevalence of psychiatric comorbidity in cocaine users recruited in non-clinical settings. Future studies examining potential differential factors associated with primary versus substance-induced disorders are necessary to optimize the implementation of more suitable approaching programmes for young regular cocaine users. SN - 0965-2140 UR - https://www.unboundmedicine.com/medline/citation/18199307/Psychiatric_comorbidity_in_young_cocaine_users:_induced_versus_independent_disorders_ DB - PRIME DP - Unbound Medicine ER -