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Antimicrobial prenylated dihydrochalcones from Eriosema glomerata.
Planta Med. 2008 Jan; 74(1):50-4.PM

Abstract

Two new natural dihydrochalcones exhibiting antimicrobial properties together with six known compounds were isolated from the Cameroonian medicinal plant Eriosema glomerata. The structures of the new dihydrochalcones were elucidated as 2',4'-dihydroxy-4-methoxy-3'-(gamma, gamma-dimethylallyl)dihydrochalcone and 2',4'-dihydroxy-3'-(gamma, gamma-dimethylallyl)dihydrochalcone by detailed spectroscopic analysis. The two new dihydrochalcones, named erioschalcones A (1) and B (2), demonstrated significant inhibitory activity against the microbial strains Bacillus megaterium, Escherichia coli, Chlorella fusca and Microbotryum violaceum.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Awouafack MD
Department of Chemistry, University of Dschang, Dschang, Cameroon.
Kouam SF
No affiliation info available
Hussain H
No affiliation info available
Ngamga D
No affiliation info available
Tane P
No affiliation info available
Schulz B
No affiliation info available
Green IR
No affiliation info available
Krohn K
No affiliation info available

MeSH

Anti-Infective AgentsChalconesChlorophytaFabaceaeGram-Negative BacteriaGram-Positive BacteriaHumansMicrobial Sensitivity TestsMitosporic FungiPhytotherapyPlant ExtractsPrenylation

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18203062

Citation

Awouafack, Maurice D., et al. "Antimicrobial Prenylated Dihydrochalcones From Eriosema Glomerata." Planta Medica, vol. 74, no. 1, 2008, pp. 50-4.
Awouafack MD, Kouam SF, Hussain H, et al. Antimicrobial prenylated dihydrochalcones from Eriosema glomerata. Planta Med. 2008;74(1):50-4.
Awouafack, M. D., Kouam, S. F., Hussain, H., Ngamga, D., Tane, P., Schulz, B., Green, I. R., & Krohn, K. (2008). Antimicrobial prenylated dihydrochalcones from Eriosema glomerata. Planta Medica, 74(1), 50-4. https://doi.org/10.1055/s-2007-993782
Awouafack MD, et al. Antimicrobial Prenylated Dihydrochalcones From Eriosema Glomerata. Planta Med. 2008;74(1):50-4. PubMed PMID: 18203062.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Antimicrobial prenylated dihydrochalcones from Eriosema glomerata. AU - Awouafack,Maurice D, AU - Kouam,Simeon F, AU - Hussain,Hidayat, AU - Ngamga,Dieudonne, AU - Tane,Pierre, AU - Schulz,Barbara, AU - Green,Ivan R, AU - Krohn,Karsten, Y1 - 2008/01/18/ PY - 2008/1/19/pubmed PY - 2008/4/16/medline PY - 2008/1/19/entrez SP - 50 EP - 4 JF - Planta medica JO - Planta Med VL - 74 IS - 1 N2 - Two new natural dihydrochalcones exhibiting antimicrobial properties together with six known compounds were isolated from the Cameroonian medicinal plant Eriosema glomerata. The structures of the new dihydrochalcones were elucidated as 2',4'-dihydroxy-4-methoxy-3'-(gamma, gamma-dimethylallyl)dihydrochalcone and 2',4'-dihydroxy-3'-(gamma, gamma-dimethylallyl)dihydrochalcone by detailed spectroscopic analysis. The two new dihydrochalcones, named erioschalcones A (1) and B (2), demonstrated significant inhibitory activity against the microbial strains Bacillus megaterium, Escherichia coli, Chlorella fusca and Microbotryum violaceum. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/18203062/Antimicrobial_prenylated_dihydrochalcones_from_Eriosema_glomerata_ DB - PRIME DP - Unbound Medicine ER -