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Exposure to maternal smoking in the first year of life interferes in breast-feeding protective effect against the onset of respiratory allergy from birth to 5 yr.
Pediatr Allergy Immunol. 2009 Feb; 20(1):30-4.PA

Abstract

The aim of this study was to evaluate the interaction between the exclusive breast-feeding protective effect and the exposure to tobacco smoke at domicile in the first year of life, on the onset of respiratory allergy (asthma and rhinitis) in children until 5 yr of age. This is prospective cohort study, observational, institutional based. Three hundred children born in a public hospital of Salvador-Bahia (Brazil) were followed from birth to 5 yr of age. Data from 268 children at 60 months of life were analyzed. Occurrence of allergic symptoms were studied and correlated with gender, allergic relatives in first degree, exclusive breast-feeding duration, smoking mother, and presence of other smoker at home, considering the first year of life. Exclusive breast-feeding for at least 6 months showed a protection effect against the onset of respiratory allergy in children from birth to 5 yr (p < 0.05); odds ratio (OR): 0.33 (95% CI: 0.18-0.59). Breast-fed children for less then 6 months compared with those breast-fed for 6 months or more, presented a higher risk (OR: 2.34-95% CI: 1.4-3.74) for developing allergic respiratory symptoms just to 5 yr. The protective effect of exclusive prolonged breast-feeding on the onset of respiratory allergy in children from birth until 5 yr was lost when their mothers were smokers (OR: 2.50-95% CI 1.19-5.19). Therefore, the protective effect of breast-feeding in the first year of life on the onset of allergic symptoms until the age of 5 yr was confirmed. This study proposes a confounding effect of maternal smoking on this protection, exposed by a higher risk for present allergic symptoms until the age of 5 yr, in children exclusively breast-fed for 6 months or more, when their mothers smoked.

Authors+Show Affiliations

School of Medicine-Salvador, Bahia, Brazil. hermila.guedes@gmail.comNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18208466

Citation

Guedes, H T V., and L S F. Souza. "Exposure to Maternal Smoking in the First Year of Life Interferes in Breast-feeding Protective Effect Against the Onset of Respiratory Allergy From Birth to 5 Yr." Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, vol. 20, no. 1, 2009, pp. 30-4.
Guedes HT, Souza LS. Exposure to maternal smoking in the first year of life interferes in breast-feeding protective effect against the onset of respiratory allergy from birth to 5 yr. Pediatr Allergy Immunol. 2009;20(1):30-4.
Guedes, H. T., & Souza, L. S. (2009). Exposure to maternal smoking in the first year of life interferes in breast-feeding protective effect against the onset of respiratory allergy from birth to 5 yr. Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology, 20(1), 30-4. https://doi.org/10.1111/j.1399-3038.2007.00710.x
Guedes HT, Souza LS. Exposure to Maternal Smoking in the First Year of Life Interferes in Breast-feeding Protective Effect Against the Onset of Respiratory Allergy From Birth to 5 Yr. Pediatr Allergy Immunol. 2009;20(1):30-4. PubMed PMID: 18208466.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Exposure to maternal smoking in the first year of life interferes in breast-feeding protective effect against the onset of respiratory allergy from birth to 5 yr. AU - Guedes,H T V, AU - Souza,L S F, Y1 - 2008/01/12/ PY - 2008/1/23/pubmed PY - 2009/2/25/medline PY - 2008/1/23/entrez SP - 30 EP - 4 JF - Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology JO - Pediatr Allergy Immunol VL - 20 IS - 1 N2 - The aim of this study was to evaluate the interaction between the exclusive breast-feeding protective effect and the exposure to tobacco smoke at domicile in the first year of life, on the onset of respiratory allergy (asthma and rhinitis) in children until 5 yr of age. This is prospective cohort study, observational, institutional based. Three hundred children born in a public hospital of Salvador-Bahia (Brazil) were followed from birth to 5 yr of age. Data from 268 children at 60 months of life were analyzed. Occurrence of allergic symptoms were studied and correlated with gender, allergic relatives in first degree, exclusive breast-feeding duration, smoking mother, and presence of other smoker at home, considering the first year of life. Exclusive breast-feeding for at least 6 months showed a protection effect against the onset of respiratory allergy in children from birth to 5 yr (p < 0.05); odds ratio (OR): 0.33 (95% CI: 0.18-0.59). Breast-fed children for less then 6 months compared with those breast-fed for 6 months or more, presented a higher risk (OR: 2.34-95% CI: 1.4-3.74) for developing allergic respiratory symptoms just to 5 yr. The protective effect of exclusive prolonged breast-feeding on the onset of respiratory allergy in children from birth until 5 yr was lost when their mothers were smokers (OR: 2.50-95% CI 1.19-5.19). Therefore, the protective effect of breast-feeding in the first year of life on the onset of allergic symptoms until the age of 5 yr was confirmed. This study proposes a confounding effect of maternal smoking on this protection, exposed by a higher risk for present allergic symptoms until the age of 5 yr, in children exclusively breast-fed for 6 months or more, when their mothers smoked. SN - 1399-3038 UR - https://www.unboundmedicine.com/medline/citation/18208466/Exposure_to_maternal_smoking_in_the_first_year_of_life_interferes_in_breast_feeding_protective_effect_against_the_onset_of_respiratory_allergy_from_birth_to_5_yr_ L2 - https://doi.org/10.1111/j.1399-3038.2007.00710.x DB - PRIME DP - Unbound Medicine ER -