Tags

Type your tag names separated by a space and hit enter

Value of different diagnostic criteria for the irritable bowel syndrome among men and women.
J Clin Gastroenterol 2008; 42(2):160-6JC

Abstract

INTRODUCTION

Whether the diagnostic value of various criteria used to diagnose irritable bowel syndrome (IBS) differ by sex is controversial.

AIM

To evaluate the sex-specific value of varying IBS criteria and sex-specific symptoms in patients with IBS and organic disease.

METHODS

Outpatients of a gastroenterology practice (64% female) completed a validated questionnaire and received a complete diagnostic work-up as required. Questionnaire data were collected prospectively and audited retrospectively.

RESULTS

Overall 233 (male 21%) had a final diagnosis of IBS; 305 (male 47%) received a diagnosis of organic disease. Constipation and bloating were more frequent in females independent whether they had IBS or organic disease. The sensitivity of the diagnostic criteria in male patients was between 82% and 88%, when Manning (3 or more), Rome I or Rome II criteria were applied, whereas the specificity was 65% to 71%. In females, sensitivity was 62% to 64% and specificity was between 66% and 70%. Although all the diagnostic IBS criteria had higher positive predictive values in females versus males, the negative predictive values were lower in females.

CONCLUSIONS

Current criteria for IBS differ modestly between sexes, probably reflecting variable prevalence of the disease rather than a sex-specific presentation of IBS.

Authors+Show Affiliations

Universitätsklinik für Innere Medizin IV, Abteilung für Gastroenterologie und Hepatologie, Vienna, Austria. Johann.hammer@meduniwien.ac.atNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18209586

Citation

Hammer, Johann, and Nicholas J. Talley. "Value of Different Diagnostic Criteria for the Irritable Bowel Syndrome Among Men and Women." Journal of Clinical Gastroenterology, vol. 42, no. 2, 2008, pp. 160-6.
Hammer J, Talley NJ. Value of different diagnostic criteria for the irritable bowel syndrome among men and women. J Clin Gastroenterol. 2008;42(2):160-6.
Hammer, J., & Talley, N. J. (2008). Value of different diagnostic criteria for the irritable bowel syndrome among men and women. Journal of Clinical Gastroenterology, 42(2), pp. 160-6. doi:10.1097/MCG.0b013e3181574d48.
Hammer J, Talley NJ. Value of Different Diagnostic Criteria for the Irritable Bowel Syndrome Among Men and Women. J Clin Gastroenterol. 2008;42(2):160-6. PubMed PMID: 18209586.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Value of different diagnostic criteria for the irritable bowel syndrome among men and women. AU - Hammer,Johann, AU - Talley,Nicholas J, PY - 2008/1/23/pubmed PY - 2008/4/2/medline PY - 2008/1/23/entrez SP - 160 EP - 6 JF - Journal of clinical gastroenterology JO - J. Clin. Gastroenterol. VL - 42 IS - 2 N2 - INTRODUCTION: Whether the diagnostic value of various criteria used to diagnose irritable bowel syndrome (IBS) differ by sex is controversial. AIM: To evaluate the sex-specific value of varying IBS criteria and sex-specific symptoms in patients with IBS and organic disease. METHODS: Outpatients of a gastroenterology practice (64% female) completed a validated questionnaire and received a complete diagnostic work-up as required. Questionnaire data were collected prospectively and audited retrospectively. RESULTS: Overall 233 (male 21%) had a final diagnosis of IBS; 305 (male 47%) received a diagnosis of organic disease. Constipation and bloating were more frequent in females independent whether they had IBS or organic disease. The sensitivity of the diagnostic criteria in male patients was between 82% and 88%, when Manning (3 or more), Rome I or Rome II criteria were applied, whereas the specificity was 65% to 71%. In females, sensitivity was 62% to 64% and specificity was between 66% and 70%. Although all the diagnostic IBS criteria had higher positive predictive values in females versus males, the negative predictive values were lower in females. CONCLUSIONS: Current criteria for IBS differ modestly between sexes, probably reflecting variable prevalence of the disease rather than a sex-specific presentation of IBS. SN - 0192-0790 UR - https://www.unboundmedicine.com/medline/citation/18209586/Value_of_different_diagnostic_criteria_for_the_irritable_bowel_syndrome_among_men_and_women_ L2 - http://Insights.ovid.com/pubmed?pmid=18209586 DB - PRIME DP - Unbound Medicine ER -