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Quality of life in older Belgian people: comparison between people with dementia, mild cognitive impairment, and controls.
Int J Geriatr Psychiatry. 2008 Nov; 23(11):1103-9.IJ

Abstract

OBJECTIVES

To assess the sensitivity of the 'Alzheimer's Disease Related Quality of Life' instrument (ADRQL) applied to Belgian people with dementia (n = 357), mild cognitive impairment (MCI) (n = 36), and controls (n = 72). We also determined the clinical parameters that influence the quality of life (QOL) of people with dementia.

METHOD

Each subject was evaluated with the ADRQL, the Mini Mental State Examination (MMSE), the cognitive scale of the Cambridge Examination for Mental Disorders of the Elderly (CAMCOG), the Katz's ADL classification (ADL), the Instrumental Activities of Daily Living (IADL), the Behavior Rating Scale for Dementia (CERAD/BRSD), and the Clinical Dementia Rating/Modified (CDR-M).

RESULTS

The ADRQL showed that QOL of the dementia group (65.77 +/- 17.04) was significantly inferior to that of the MCI (82.11 +/- 13.31) and control groups (79.75 +/- 15.82). There were no significant differences between the MCI and control groups. Within the dementia group, the five ADRQL subscale results were similar to those reported in other studies. Gender, age and place of residence had no significant influence on ADRQL scores. In contrast, ADRQL scores correlated significantly with MMSE, CAMCOG, IADL, ADL, CERAD/BRSD, and CDR-M. The MMSE and CERAD/BRSD were significant predictors of ADRQL variability.

CONCLUSIONS

QOL of people with dementia is inferior to that of people with MCI and controls. This demonstrates the ADRQL instrument is sufficiently sensitive for evaluating the QOL of people with dementia. Longitudinal studies are needed to specifically examine the rate of QOL evolution throughout the entire dementia process.

Authors+Show Affiliations

Faculty of Psychology, University of Liège, Liège, Belgium. pmissotten@ulg.ac.beNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Multicenter Study
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18213606

Citation

Missotten, Pierre, et al. "Quality of Life in Older Belgian People: Comparison Between People With Dementia, Mild Cognitive Impairment, and Controls." International Journal of Geriatric Psychiatry, vol. 23, no. 11, 2008, pp. 1103-9.
Missotten P, Squelard G, Ylieff M, et al. Quality of life in older Belgian people: comparison between people with dementia, mild cognitive impairment, and controls. Int J Geriatr Psychiatry. 2008;23(11):1103-9.
Missotten, P., Squelard, G., Ylieff, M., Di Notte, D., Paquay, L., De Lepeleire, J., & Fontaine, O. (2008). Quality of life in older Belgian people: comparison between people with dementia, mild cognitive impairment, and controls. International Journal of Geriatric Psychiatry, 23(11), 1103-9. https://doi.org/10.1002/gps.1981
Missotten P, et al. Quality of Life in Older Belgian People: Comparison Between People With Dementia, Mild Cognitive Impairment, and Controls. Int J Geriatr Psychiatry. 2008;23(11):1103-9. PubMed PMID: 18213606.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Quality of life in older Belgian people: comparison between people with dementia, mild cognitive impairment, and controls. AU - Missotten,Pierre, AU - Squelard,Gilles, AU - Ylieff,Michel, AU - Di Notte,David, AU - Paquay,Louis, AU - De Lepeleire,Jan, AU - Fontaine,Ovide, PY - 2008/1/24/pubmed PY - 2009/5/22/medline PY - 2008/1/24/entrez SP - 1103 EP - 9 JF - International journal of geriatric psychiatry JO - Int J Geriatr Psychiatry VL - 23 IS - 11 N2 - OBJECTIVES: To assess the sensitivity of the 'Alzheimer's Disease Related Quality of Life' instrument (ADRQL) applied to Belgian people with dementia (n = 357), mild cognitive impairment (MCI) (n = 36), and controls (n = 72). We also determined the clinical parameters that influence the quality of life (QOL) of people with dementia. METHOD: Each subject was evaluated with the ADRQL, the Mini Mental State Examination (MMSE), the cognitive scale of the Cambridge Examination for Mental Disorders of the Elderly (CAMCOG), the Katz's ADL classification (ADL), the Instrumental Activities of Daily Living (IADL), the Behavior Rating Scale for Dementia (CERAD/BRSD), and the Clinical Dementia Rating/Modified (CDR-M). RESULTS: The ADRQL showed that QOL of the dementia group (65.77 +/- 17.04) was significantly inferior to that of the MCI (82.11 +/- 13.31) and control groups (79.75 +/- 15.82). There were no significant differences between the MCI and control groups. Within the dementia group, the five ADRQL subscale results were similar to those reported in other studies. Gender, age and place of residence had no significant influence on ADRQL scores. In contrast, ADRQL scores correlated significantly with MMSE, CAMCOG, IADL, ADL, CERAD/BRSD, and CDR-M. The MMSE and CERAD/BRSD were significant predictors of ADRQL variability. CONCLUSIONS: QOL of people with dementia is inferior to that of people with MCI and controls. This demonstrates the ADRQL instrument is sufficiently sensitive for evaluating the QOL of people with dementia. Longitudinal studies are needed to specifically examine the rate of QOL evolution throughout the entire dementia process. SN - 1099-1166 UR - https://www.unboundmedicine.com/medline/citation/18213606/Quality_of_life_in_older_Belgian_people:_comparison_between_people_with_dementia_mild_cognitive_impairment_and_controls_ L2 - https://doi.org/10.1002/gps.1981 DB - PRIME DP - Unbound Medicine ER -