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Marine mimivirus relatives are probably large algal viruses.
Virol J. 2008 Jan 23; 5:12.VJ

Abstract

BACKGROUND

Acanthamoeba polyphaga mimivirus is the largest known ds-DNA virus and its 1.2 Mb-genome sequence has revealed many unique features. Mimivirus occupies an independent lineage among eukaryotic viruses and its known hosts include only species from the Acanthamoeba genus. The existence of mimivirus relatives was first suggested by the analysis of the Sargasso Sea metagenomic data.

RESULTS

We now further demonstrate the presence of numerous "mimivirus-like" sequences using a larger marine metagenomic data set. We also show that the DNA polymerase sequences from three algal viruses (CeV01, PpV01, PoV01) infecting different marine algal species (Chrysochromulina ericina, Phaeocystis pouchetii, Pyramimonas orientalis) are very closely related to their homolog in mimivirus.

CONCLUSION

Our results suggest that the numerous mimivirus-related sequences identified in marine environments are likely to originate from diverse large DNA viruses infecting phytoplankton. Micro-algae thus constitute a new category of potential hosts in which to look for new species of Mimiviridae.

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Authors+Show Affiliations

Monier A
Structural and Genomic Information Laboratory, CNRS-UPR 2589, IBSM, Parc Scientifique de Luminy, 163 avenue de Luminy, Case 934, 13288 Marseille Cedex 9, France. adam.monier@igs.cnrs-mrs.fr
Larsen JB
No affiliation info available
Sandaa RA
No affiliation info available
Bratbak G
No affiliation info available
Claverie JM
No affiliation info available
Ogata H
No affiliation info available

MeSH

AcanthamoebaAnimalsDNA VirusesDNA-Directed DNA PolymeraseMarine BiologyOceans and SeasOpen Reading FramesPhycodnaviridaePhylogenyPhytoplankton

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18215256

Citation

Monier, Adam, et al. "Marine Mimivirus Relatives Are Probably Large Algal Viruses." Virology Journal, vol. 5, 2008, p. 12.
Monier A, Larsen JB, Sandaa RA, et al. Marine mimivirus relatives are probably large algal viruses. Virol J. 2008;5:12.
Monier, A., Larsen, J. B., Sandaa, R. A., Bratbak, G., Claverie, J. M., & Ogata, H. (2008). Marine mimivirus relatives are probably large algal viruses. Virology Journal, 5, 12. https://doi.org/10.1186/1743-422X-5-12
Monier A, et al. Marine Mimivirus Relatives Are Probably Large Algal Viruses. Virol J. 2008 Jan 23;5:12. PubMed PMID: 18215256.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Marine mimivirus relatives are probably large algal viruses. AU - Monier,Adam, AU - Larsen,Jens Borggaard, AU - Sandaa,Ruth-Anne, AU - Bratbak,Gunnar, AU - Claverie,Jean-Michel, AU - Ogata,Hiroyuki, Y1 - 2008/01/23/ PY - 2007/11/09/received PY - 2008/01/23/accepted PY - 2008/1/25/pubmed PY - 2008/3/19/medline PY - 2008/1/25/entrez SP - 12 EP - 12 JF - Virology journal JO - Virol J VL - 5 N2 - BACKGROUND: Acanthamoeba polyphaga mimivirus is the largest known ds-DNA virus and its 1.2 Mb-genome sequence has revealed many unique features. Mimivirus occupies an independent lineage among eukaryotic viruses and its known hosts include only species from the Acanthamoeba genus. The existence of mimivirus relatives was first suggested by the analysis of the Sargasso Sea metagenomic data. RESULTS: We now further demonstrate the presence of numerous "mimivirus-like" sequences using a larger marine metagenomic data set. We also show that the DNA polymerase sequences from three algal viruses (CeV01, PpV01, PoV01) infecting different marine algal species (Chrysochromulina ericina, Phaeocystis pouchetii, Pyramimonas orientalis) are very closely related to their homolog in mimivirus. CONCLUSION: Our results suggest that the numerous mimivirus-related sequences identified in marine environments are likely to originate from diverse large DNA viruses infecting phytoplankton. Micro-algae thus constitute a new category of potential hosts in which to look for new species of Mimiviridae. SN - 1743-422X UR - https://www.unboundmedicine.com/medline/citation/18215256/Marine_mimivirus_relatives_are_probably_large_algal_viruses_ DB - PRIME DP - Unbound Medicine ER -