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Persons with varicose veins have a high subsequent incidence of arterial disease: a population-based study in Tampere, Finland.
Angiology. 2007 Dec-2008 Jan; 58(6):704-9.A

Abstract

The aim of this population research was to find out the risk of arterial disease (defined as angina pectoris, myocardial infarction, peripheral occlusive arterial disease, and cerebrovascular disease) and hypertension in persons with varicose veins. A 5-year follow-up study was conducted in Tampere, Finland. A validated questionnaire was used in 3 middle-aged cohorts (40, 50, and 60 year olds) in a general population of 6,874. In the follow-up study, 71% (n = 4,903) replied. The incidence of arterial disease and hypertension was studied in those with varicose veins and those without at the entry to the study. During the follow-up, new arterial disease occurred significantly more often in individuals with varicose veins. The incidence odds ratio was 2.0 (95% confidence interval, 1.5-2.7; n = 3,032), but the incidence odds ratio of new hypertension was 1.0 (95% confidence interval, 0.8-1.3; n = 2,915). Varicose veins are a risk indicator of arterial disease but not of hypertension. Varicose veins likely do not cause arterial disease, but they may have common causes that, however, are not related with hypertension.

Authors+Show Affiliations

School of Public Health, University of Tampere, Tampere, Finland. liisa.makivaara@uta.fiNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18216380

Citation

Mäkivaara, Liisa A., et al. "Persons With Varicose Veins Have a High Subsequent Incidence of Arterial Disease: a Population-based Study in Tampere, Finland." Angiology, vol. 58, no. 6, 2008, pp. 704-9.
Mäkivaara LA, Ahti TM, Luukkaala T, et al. Persons with varicose veins have a high subsequent incidence of arterial disease: a population-based study in Tampere, Finland. Angiology. 2008;58(6):704-9.
Mäkivaara, L. A., Ahti, T. M., Luukkaala, T., Hakama, M., & Laurikka, J. O. (2008). Persons with varicose veins have a high subsequent incidence of arterial disease: a population-based study in Tampere, Finland. Angiology, 58(6), 704-9. https://doi.org/10.1177/0003319707299202
Mäkivaara LA, et al. Persons With Varicose Veins Have a High Subsequent Incidence of Arterial Disease: a Population-based Study in Tampere, Finland. Angiology. 2007 Dec-2008 Jan;58(6):704-9. PubMed PMID: 18216380.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Persons with varicose veins have a high subsequent incidence of arterial disease: a population-based study in Tampere, Finland. AU - Mäkivaara,Liisa A, AU - Ahti,Tiina M, AU - Luukkaala,Tiina, AU - Hakama,Matti, AU - Laurikka,Jari O, PY - 2008/1/25/pubmed PY - 2008/2/8/medline PY - 2008/1/25/entrez SP - 704 EP - 9 JF - Angiology JO - Angiology VL - 58 IS - 6 N2 - The aim of this population research was to find out the risk of arterial disease (defined as angina pectoris, myocardial infarction, peripheral occlusive arterial disease, and cerebrovascular disease) and hypertension in persons with varicose veins. A 5-year follow-up study was conducted in Tampere, Finland. A validated questionnaire was used in 3 middle-aged cohorts (40, 50, and 60 year olds) in a general population of 6,874. In the follow-up study, 71% (n = 4,903) replied. The incidence of arterial disease and hypertension was studied in those with varicose veins and those without at the entry to the study. During the follow-up, new arterial disease occurred significantly more often in individuals with varicose veins. The incidence odds ratio was 2.0 (95% confidence interval, 1.5-2.7; n = 3,032), but the incidence odds ratio of new hypertension was 1.0 (95% confidence interval, 0.8-1.3; n = 2,915). Varicose veins are a risk indicator of arterial disease but not of hypertension. Varicose veins likely do not cause arterial disease, but they may have common causes that, however, are not related with hypertension. SN - 0003-3197 UR - https://www.unboundmedicine.com/medline/citation/18216380/Persons_with_varicose_veins_have_a_high_subsequent_incidence_of_arterial_disease:_a_population_based_study_in_Tampere_Finland_ L2 - https://journals.sagepub.com/doi/10.1177/0003319707299202?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -