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Diffusion-weighted imaging in normal prostate and differential diagnosis of prostate diseases.
Abdom Imaging. 2008 Nov-Dec; 33(6):724-8.AI

Abstract

BACKGROUND

During the past several years, the morbidities of prostate diseases have increased sharply all over the world. Diffusion-weighted imaging (DWI) is an MR-based technique that probes the function of tissues. We attempt to investigate the diagnostic value of DWI and apparent diffusion coefficient (ADC) in normal prostate gland and prostate diseases.

MATERIALS AND METHODS

A total of 16 healthy volunteers, 9 prostate cysts, 29 benign prostatic hyperplasia (BPH), and 21 prostatic carcinoma (Pca) underwent DWI, respectively. Their DWI and ADC characteristics were analyzed, and the diagnostic and differential diagnostic values of DWI and ADC were summarized. All of the BPH and Pca received a histological diagnosis.

RESULTS

In DWI, the signal intensity of BPH nodule was nonhomogeneous and lower than that of the peripheral zone (PZ). Pca showed high signal intensity while the prostate cyst showed low intensity. The mean ADCs for the normal central gland, PZ, prostate cyst, BPH nodules, and Pca foci were (1.352 +/- 0.052) x 10(-3)mm(2)/s, (1.829 +/- 0.071) x 10(-3)mm(2)/s, (2.557 +/- 0.084) x 10(-3)mm(2)/s, (1.576 +/- 0.101) x 10(-3)mm(2)/s, and (0.934 +/- 0.166) x 10(-3)mm(2)/s, respectively (P = 0.000).

CONCLUSIONS

Diffusion-weighted imaging and ADCs for the normal central gland, PZ, prostate cyst, BPH nodules, and Pca demonstrate significant differences, and those can be used in the diagnosis and differential diagnosis of the diseases of prostate.

Authors+Show Affiliations

Department of Radiology, Xijing Hospital, Fourth Military Medical University, Chang Le Western Road No. 15, Xi'an, 710032, People's Republic of China.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

eng

PubMed ID

18219519

Citation

Ren, Jing, et al. "Diffusion-weighted Imaging in Normal Prostate and Differential Diagnosis of Prostate Diseases." Abdominal Imaging, vol. 33, no. 6, 2008, pp. 724-8.
Ren J, Huan Y, Wang H, et al. Diffusion-weighted imaging in normal prostate and differential diagnosis of prostate diseases. Abdom Imaging. 2008;33(6):724-8.
Ren, J., Huan, Y., Wang, H., Zhao, H., Ge, Y., Chang, Y., & Liu, Y. (2008). Diffusion-weighted imaging in normal prostate and differential diagnosis of prostate diseases. Abdominal Imaging, 33(6), 724-8. https://doi.org/10.1007/s00261-008-9361-2
Ren J, et al. Diffusion-weighted Imaging in Normal Prostate and Differential Diagnosis of Prostate Diseases. Abdom Imaging. 2008 Nov-Dec;33(6):724-8. PubMed PMID: 18219519.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Diffusion-weighted imaging in normal prostate and differential diagnosis of prostate diseases. AU - Ren,Jing, AU - Huan,Yi, AU - Wang,He, AU - Zhao,HaiTao, AU - Ge,YaLi, AU - Chang,YingJuan, AU - Liu,Ying, PY - 2008/1/26/pubmed PY - 2009/2/12/medline PY - 2008/1/26/entrez SP - 724 EP - 8 JF - Abdominal imaging JO - Abdom Imaging VL - 33 IS - 6 N2 - BACKGROUND: During the past several years, the morbidities of prostate diseases have increased sharply all over the world. Diffusion-weighted imaging (DWI) is an MR-based technique that probes the function of tissues. We attempt to investigate the diagnostic value of DWI and apparent diffusion coefficient (ADC) in normal prostate gland and prostate diseases. MATERIALS AND METHODS: A total of 16 healthy volunteers, 9 prostate cysts, 29 benign prostatic hyperplasia (BPH), and 21 prostatic carcinoma (Pca) underwent DWI, respectively. Their DWI and ADC characteristics were analyzed, and the diagnostic and differential diagnostic values of DWI and ADC were summarized. All of the BPH and Pca received a histological diagnosis. RESULTS: In DWI, the signal intensity of BPH nodule was nonhomogeneous and lower than that of the peripheral zone (PZ). Pca showed high signal intensity while the prostate cyst showed low intensity. The mean ADCs for the normal central gland, PZ, prostate cyst, BPH nodules, and Pca foci were (1.352 +/- 0.052) x 10(-3)mm(2)/s, (1.829 +/- 0.071) x 10(-3)mm(2)/s, (2.557 +/- 0.084) x 10(-3)mm(2)/s, (1.576 +/- 0.101) x 10(-3)mm(2)/s, and (0.934 +/- 0.166) x 10(-3)mm(2)/s, respectively (P = 0.000). CONCLUSIONS: Diffusion-weighted imaging and ADCs for the normal central gland, PZ, prostate cyst, BPH nodules, and Pca demonstrate significant differences, and those can be used in the diagnosis and differential diagnosis of the diseases of prostate. SN - 1432-0509 UR - https://www.unboundmedicine.com/medline/citation/18219519/Diffusion_weighted_imaging_in_normal_prostate_and_differential_diagnosis_of_prostate_diseases_ L2 - https://dx.doi.org/10.1007/s00261-008-9361-2 DB - PRIME DP - Unbound Medicine ER -