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Relationship between soy and isoflavone intake and periodontal disease: the Freshmen in Dietetic Courses Study II.
BMC Public Health. 2008 Jan 29; 8:39.BP

Abstract

BACKGROUND

Much research has shown that soy products inhibited various diseases. However, no published studies have examined the effects of consumption of soy and isoflavones on periodontal disease. The aim of this study was to investigate whether soy and isoflavone intake is associated with the prevalence of periodontal disease.

METHODS

The subjects were 3956 Japanese female students, aged 18 to 22 years, who were taking a dietetic course. Periodontal disease was defined as present when a subject reported diagnosis of the disorder by a dentist. Information on dietary factors was collected using a validated diet history questionnaire. Logistic regression analysis was used to estimate the odds ratios and their confidence intervals of periodontal disease. Adjustment was made for cigarette smoking, toothbrushing frequency, region of residence, and body mass index.

RESULTS

The prevalence of periodontal disease was 8.0%. Intake of total soy product and tofu was independently associated with a decreased prevalence of periodontal disease; multivariate odds ratios in comparison of the highest with the lowest quintile were 0.68 and 0.68, respectively (95% confidence intervals = 0.47-0.97 and 0.47-0.98, P for trend = 0.01 and 0.004, respectively). A significant inverse dose-response relationship between the intake of isoflavones and the prevalence of periodontal disease was observed, although the difference in the adjusted odds ratio between the extreme quintiles was of borderline significance (P for trend = 0.04). There were no measurable dose-response relationships between consumption of tofu products, fermented soybeans, boiled soybeans, miso, or miso soup and the prevalence of periodontal disease.

CONCLUSION

Our findings suggest that soy and isoflavone intake may decrease the likelihood of periodontal disease. Further investigations with objective measures for periodontal disease are needed to confirm our findings.

Authors+Show Affiliations

Department of Public Health, Faculty of Medicine, Fukuoka University, Fukuoka, Japan. k-tanaka@fukuoka-u.ac.jpNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18226266

Citation

Tanaka, Keiko, et al. "Relationship Between Soy and Isoflavone Intake and Periodontal Disease: the Freshmen in Dietetic Courses Study II." BMC Public Health, vol. 8, 2008, p. 39.
Tanaka K, Sasaki S, Murakami K, et al. Relationship between soy and isoflavone intake and periodontal disease: the Freshmen in Dietetic Courses Study II. BMC Public Health. 2008;8:39.
Tanaka, K., Sasaki, S., Murakami, K., Okubo, H., Takahashi, Y., & Miyake, Y. (2008). Relationship between soy and isoflavone intake and periodontal disease: the Freshmen in Dietetic Courses Study II. BMC Public Health, 8, 39. https://doi.org/10.1186/1471-2458-8-39
Tanaka K, et al. Relationship Between Soy and Isoflavone Intake and Periodontal Disease: the Freshmen in Dietetic Courses Study II. BMC Public Health. 2008 Jan 29;8:39. PubMed PMID: 18226266.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Relationship between soy and isoflavone intake and periodontal disease: the Freshmen in Dietetic Courses Study II. AU - Tanaka,Keiko, AU - Sasaki,Satoshi, AU - Murakami,Kentaro, AU - Okubo,Hitomi, AU - Takahashi,Yoshiko, AU - Miyake,Yoshihiro, AU - ,, Y1 - 2008/01/29/ PY - 2007/01/23/received PY - 2008/01/29/accepted PY - 2008/1/30/pubmed PY - 2008/11/19/medline PY - 2008/1/30/entrez SP - 39 EP - 39 JF - BMC public health JO - BMC Public Health VL - 8 N2 - BACKGROUND: Much research has shown that soy products inhibited various diseases. However, no published studies have examined the effects of consumption of soy and isoflavones on periodontal disease. The aim of this study was to investigate whether soy and isoflavone intake is associated with the prevalence of periodontal disease. METHODS: The subjects were 3956 Japanese female students, aged 18 to 22 years, who were taking a dietetic course. Periodontal disease was defined as present when a subject reported diagnosis of the disorder by a dentist. Information on dietary factors was collected using a validated diet history questionnaire. Logistic regression analysis was used to estimate the odds ratios and their confidence intervals of periodontal disease. Adjustment was made for cigarette smoking, toothbrushing frequency, region of residence, and body mass index. RESULTS: The prevalence of periodontal disease was 8.0%. Intake of total soy product and tofu was independently associated with a decreased prevalence of periodontal disease; multivariate odds ratios in comparison of the highest with the lowest quintile were 0.68 and 0.68, respectively (95% confidence intervals = 0.47-0.97 and 0.47-0.98, P for trend = 0.01 and 0.004, respectively). A significant inverse dose-response relationship between the intake of isoflavones and the prevalence of periodontal disease was observed, although the difference in the adjusted odds ratio between the extreme quintiles was of borderline significance (P for trend = 0.04). There were no measurable dose-response relationships between consumption of tofu products, fermented soybeans, boiled soybeans, miso, or miso soup and the prevalence of periodontal disease. CONCLUSION: Our findings suggest that soy and isoflavone intake may decrease the likelihood of periodontal disease. Further investigations with objective measures for periodontal disease are needed to confirm our findings. SN - 1471-2458 UR - https://www.unboundmedicine.com/medline/citation/18226266/Relationship_between_soy_and_isoflavone_intake_and_periodontal_disease:_the_Freshmen_in_Dietetic_Courses_Study_II_ L2 - https://bmcpublichealth.biomedcentral.com/articles/10.1186/1471-2458-8-39 DB - PRIME DP - Unbound Medicine ER -