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BMI vs. waist circumference for identifying vascular risk.
Obesity (Silver Spring). 2008 Feb; 16(2):463-9.O

Abstract

OBJECTIVE

Current guidelines recommend measurement of both BMI and waist circumference (WC) in individuals with BMI between 25.0 and 34.9 kg/m(2). We investigated the relative contributions of BMI and WC toward identifying risk of adverse vascular events in a community-based sample.

METHODS AND PROCEDURES

We evaluated Framingham Study participants (n = 4,195 person-examinations, 53% women) using pooled logistic regression to assess the incremental prognostic utility of WC in predicting risk of a first cardiovascular disease (CVD) event in the three BMI categories (normal, <25 kg/m(2); overweight, 25 to <30 kg/m(2); obese, > or =30 kg/m(2)) and to assess the incremental prognostic utility of BMI and WC separately for predicting risk of a first cardiovascular event.

RESULTS

On follow-up (16 years), 430 participants (158 women) had experienced a first CVD event. In overweight women, but not in overweight men, larger WC was found to be an independent predictor of CVD incidence, longitudinally (in women, multivariable-adjusted odds ratio (OR) per s.d. increment in WC 1.86, 95% confidence interval (CI) = 1.03-3.36, P = 0.04; in men adjusted OR per s.d. increment in WC 0.91, 95% CI 0.60-1.38, P = 0.66). In obese individuals and in those with normal BMI, WC was not associated independently with incident CVD. When BMI and WC were analyzed separately for predicting risk of a first cardiovascular event, the c statistics associated with the multivariable CVD models incorporating BMI vs. WC were nearly identical in men and women.

DISCUSSION

Knowledge of WC aids identification of vascular risk among overweight women. Among normal weight or obese women and men (regardless of BMI category) WC did not appear to substantially add to prediction of risk of vascular events.

Authors+Show Affiliations

Center for Research on Health Care, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA. freibergms@upmc.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18239660

Citation

Freiberg, Matthew S., et al. "BMI Vs. Waist Circumference for Identifying Vascular Risk." Obesity (Silver Spring, Md.), vol. 16, no. 2, 2008, pp. 463-9.
Freiberg MS, Pencina MJ, D'Agostino RB, et al. BMI vs. waist circumference for identifying vascular risk. Obesity (Silver Spring). 2008;16(2):463-9.
Freiberg, M. S., Pencina, M. J., D'Agostino, R. B., Lanier, K., Wilson, P. W., & Vasan, R. S. (2008). BMI vs. waist circumference for identifying vascular risk. Obesity (Silver Spring, Md.), 16(2), 463-9. https://doi.org/10.1038/oby.2007.75
Freiberg MS, et al. BMI Vs. Waist Circumference for Identifying Vascular Risk. Obesity (Silver Spring). 2008;16(2):463-9. PubMed PMID: 18239660.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - BMI vs. waist circumference for identifying vascular risk. AU - Freiberg,Matthew S, AU - Pencina,Michael J, AU - D'Agostino,Ralph B, AU - Lanier,Katherine, AU - Wilson,Peter W F, AU - Vasan,Ramachandran S, PY - 2008/2/2/pubmed PY - 2008/5/8/medline PY - 2008/2/2/entrez SP - 463 EP - 9 JF - Obesity (Silver Spring, Md.) JO - Obesity (Silver Spring) VL - 16 IS - 2 N2 - OBJECTIVE: Current guidelines recommend measurement of both BMI and waist circumference (WC) in individuals with BMI between 25.0 and 34.9 kg/m(2). We investigated the relative contributions of BMI and WC toward identifying risk of adverse vascular events in a community-based sample. METHODS AND PROCEDURES: We evaluated Framingham Study participants (n = 4,195 person-examinations, 53% women) using pooled logistic regression to assess the incremental prognostic utility of WC in predicting risk of a first cardiovascular disease (CVD) event in the three BMI categories (normal, <25 kg/m(2); overweight, 25 to <30 kg/m(2); obese, > or =30 kg/m(2)) and to assess the incremental prognostic utility of BMI and WC separately for predicting risk of a first cardiovascular event. RESULTS: On follow-up (16 years), 430 participants (158 women) had experienced a first CVD event. In overweight women, but not in overweight men, larger WC was found to be an independent predictor of CVD incidence, longitudinally (in women, multivariable-adjusted odds ratio (OR) per s.d. increment in WC 1.86, 95% confidence interval (CI) = 1.03-3.36, P = 0.04; in men adjusted OR per s.d. increment in WC 0.91, 95% CI 0.60-1.38, P = 0.66). In obese individuals and in those with normal BMI, WC was not associated independently with incident CVD. When BMI and WC were analyzed separately for predicting risk of a first cardiovascular event, the c statistics associated with the multivariable CVD models incorporating BMI vs. WC were nearly identical in men and women. DISCUSSION: Knowledge of WC aids identification of vascular risk among overweight women. Among normal weight or obese women and men (regardless of BMI category) WC did not appear to substantially add to prediction of risk of vascular events. SN - 1930-7381 UR - https://www.unboundmedicine.com/medline/citation/18239660/BMI_vs__waist_circumference_for_identifying_vascular_risk_ L2 - https://doi.org/10.1038/oby.2007.75 DB - PRIME DP - Unbound Medicine ER -