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Chemical and antibacterial constituents of Skimmia anquetelia.
Planta Med. 2008 Feb; 74(2):175-7.PM

Abstract

Investigation of the leaves of Skimmia anquetelia (Rutaceae) led to the isolation of a new coumarin glucoside 7,8-dihdroxy-6-[3'-beta- D-glucopyranosyloxy-2'(xi)-hydroxy-3'-methylbutyl]-coumarin (1) together with five known coumarins: 6-(2,3-dihydroxy-3-methylbutyl)-7-methoxycoumarin (2), skimmin (3), osthol (4), esculetin (5) and scopuletin (6). The antibacterial activity of compounds 1 and 3 was also investigated against the plant bacterial pathogens Agrobacterium tumifaciens, Pseudomonas syringae and Pactobacterium carotovorum. Structures were determined on the basis of analyses of spectral evidence including 1D, 2 D NMR (COSY, HMQC, HMBC and NOESY) and mass spectroscopy.

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Publisher Full Text (DOI)

Authors+Show Affiliations

Sharma RK
Department of Chemistry, HNB Garhwal University, Srinagar (Garhwal), Uttarakhand, India.
Negi DS
No affiliation info available
Gibbons S
No affiliation info available
Otsuka H
No affiliation info available

MeSH

Anti-Bacterial AgentsCoumarinsGram-Negative BacteriaMagnetic Resonance SpectroscopyMethanolPlant ExtractsRutaceae

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18240101

Citation

Sharma, Rajni Kant, et al. "Chemical and Antibacterial Constituents of Skimmia Anquetelia." Planta Medica, vol. 74, no. 2, 2008, pp. 175-7.
Sharma RK, Negi DS, Gibbons S, et al. Chemical and antibacterial constituents of Skimmia anquetelia. Planta Med. 2008;74(2):175-7.
Sharma, R. K., Negi, D. S., Gibbons, S., & Otsuka, H. (2008). Chemical and antibacterial constituents of Skimmia anquetelia. Planta Medica, 74(2), 175-7. https://doi.org/10.1055/s-2008-1034281
Sharma RK, et al. Chemical and Antibacterial Constituents of Skimmia Anquetelia. Planta Med. 2008;74(2):175-7. PubMed PMID: 18240101.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Chemical and antibacterial constituents of Skimmia anquetelia. AU - Sharma,Rajni Kant, AU - Negi,Devendra Singh, AU - Gibbons,Simon, AU - Otsuka,Hideaki, Y1 - 2008/01/31/ PY - 2008/2/2/pubmed PY - 2008/5/22/medline PY - 2008/2/2/entrez SP - 175 EP - 7 JF - Planta medica JO - Planta Med VL - 74 IS - 2 N2 - Investigation of the leaves of Skimmia anquetelia (Rutaceae) led to the isolation of a new coumarin glucoside 7,8-dihdroxy-6-[3'-beta- D-glucopyranosyloxy-2'(xi)-hydroxy-3'-methylbutyl]-coumarin (1) together with five known coumarins: 6-(2,3-dihydroxy-3-methylbutyl)-7-methoxycoumarin (2), skimmin (3), osthol (4), esculetin (5) and scopuletin (6). The antibacterial activity of compounds 1 and 3 was also investigated against the plant bacterial pathogens Agrobacterium tumifaciens, Pseudomonas syringae and Pactobacterium carotovorum. Structures were determined on the basis of analyses of spectral evidence including 1D, 2 D NMR (COSY, HMQC, HMBC and NOESY) and mass spectroscopy. SN - 0032-0943 UR - https://www.unboundmedicine.com/medline/citation/18240101/Chemical_and_antibacterial_constituents_of_Skimmia_anquetelia_ DB - PRIME DP - Unbound Medicine ER -