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Efficacy of monochromatic excimer light (308 nm) in the treatment of atopic dermatitis in adults and children.
Photomed Laser Surg. 2008 Feb; 26(1):14-8.PL

Abstract

OBJECTIVE

To demonstrate the efficacy of light produced by a 308 nm xenon-chloride monochromatic excimer light (MEL) in the treatment of localized lesions of atopic dermatitis (AD) in adults and in children.

BACKGROUND DATA

The 308-nm excimer light has been reported to be safe and effective in the treatment of chronic skin diseases, although the range of potential applications has not been fully explored.

METHODS

Twelve adults and six children affected by localized lesions of AD were enrolled in this pilot study and treated with a weekly session of MEL. A range of 6-12 sessions was performed with an increasing dosage according to the patient's phototype and response. Follow-up was for 16 wk.

RESULTS

All patients completed the protocol. At the end of treatment complete remission was observed in 12/18 patients (66.7%), a partial remission in 3/18 (16.7%) and no remission in 3/18 (16.7%). A mean total dose of 21.89 minimal erythemal dose (MED) was performed. Forty-four percent of patients maintained the results achieved at a 16-week follow-up. Treatment was well tolerated overall.

CONCLUSIONS

MEL can be considered as a valid and safe therapeutic option for the treatment of localized AD in adults and children.

Authors+Show Affiliations

Department of Dermatology, Policlinico Tor Vergata, Rome, Italy. steven.nistico@virgilio.itNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article

Language

eng

PubMed ID

18248156

Citation

Nisticò, Steven Paul, et al. "Efficacy of Monochromatic Excimer Light (308 Nm) in the Treatment of Atopic Dermatitis in Adults and Children." Photomedicine and Laser Surgery, vol. 26, no. 1, 2008, pp. 14-8.
Nisticò SP, Saraceno R, Capriotti E, et al. Efficacy of monochromatic excimer light (308 nm) in the treatment of atopic dermatitis in adults and children. Photomed Laser Surg. 2008;26(1):14-8.
Nisticò, S. P., Saraceno, R., Capriotti, E., Felice, C. D., & Chimenti, S. (2008). Efficacy of monochromatic excimer light (308 nm) in the treatment of atopic dermatitis in adults and children. Photomedicine and Laser Surgery, 26(1), 14-8. https://doi.org/10.1089/pho.2007.2116
Nisticò SP, et al. Efficacy of Monochromatic Excimer Light (308 Nm) in the Treatment of Atopic Dermatitis in Adults and Children. Photomed Laser Surg. 2008;26(1):14-8. PubMed PMID: 18248156.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Efficacy of monochromatic excimer light (308 nm) in the treatment of atopic dermatitis in adults and children. AU - Nisticò,Steven Paul, AU - Saraceno,Rosita, AU - Capriotti,Elisabetta, AU - Felice,Catia De, AU - Chimenti,Sergio, PY - 2008/2/6/pubmed PY - 2008/4/18/medline PY - 2008/2/6/entrez SP - 14 EP - 8 JF - Photomedicine and laser surgery JO - Photomed Laser Surg VL - 26 IS - 1 N2 - OBJECTIVE: To demonstrate the efficacy of light produced by a 308 nm xenon-chloride monochromatic excimer light (MEL) in the treatment of localized lesions of atopic dermatitis (AD) in adults and in children. BACKGROUND DATA: The 308-nm excimer light has been reported to be safe and effective in the treatment of chronic skin diseases, although the range of potential applications has not been fully explored. METHODS: Twelve adults and six children affected by localized lesions of AD were enrolled in this pilot study and treated with a weekly session of MEL. A range of 6-12 sessions was performed with an increasing dosage according to the patient's phototype and response. Follow-up was for 16 wk. RESULTS: All patients completed the protocol. At the end of treatment complete remission was observed in 12/18 patients (66.7%), a partial remission in 3/18 (16.7%) and no remission in 3/18 (16.7%). A mean total dose of 21.89 minimal erythemal dose (MED) was performed. Forty-four percent of patients maintained the results achieved at a 16-week follow-up. Treatment was well tolerated overall. CONCLUSIONS: MEL can be considered as a valid and safe therapeutic option for the treatment of localized AD in adults and children. SN - 1549-5418 UR - https://www.unboundmedicine.com/medline/citation/18248156/Efficacy_of_monochromatic_excimer_light__308_nm__in_the_treatment_of_atopic_dermatitis_in_adults_and_children_ L2 - https://www.liebertpub.com/doi/full/10.1089/pho.2007.2116?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -