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[Effectiveness of screening colonoscopy in a community-based study].
Z Gastroenterol 2008; 46(2):193-200ZG

Abstract

In 2002 screening colonoscopy was introduced in Germany for the prevention of colorectal cancer (CRC) and CRC mortality. Individuals took part in a prospective study from October 2002 until September 2005 performed at a single centre for gastroenterology. Histopathological data, surgical-pathological stages and further follow-up events were recorded until 31st of December 2006. For screened individuals without symptoms, the data obtained were compared to those from age-matched patients who presented with clinical symptoms/signs and who underwent colonoscopy during the same period in time. A total of 5066 individuals underwent screening colonoscopy. In this group, colorectal cancer was detected in 46 individuals (0.9%). Endoscopic treatment was considered adequate for 21 cancers. In this group of 46 patients, 94.5% were classified into UICC stages I-II by pathological staging. In 504 screened individuals, colorectal polyps were detected (12.2%) and removed by polypectomy. Of these polyps, 16 were classified as cancer, 496 as adenomas and 1 as a carcinoid tumour. High grade dysplasia was noted in 41 polyps (8.3% of adenomas). In comparison, 4099 symptomatic patients underwent colonoscopy. In this group 100 cancers (2.4%) were detected. Advanced malignant tumours were noted in 39% of these; endoscopic treatment was feasible in 16% of the cancers. As of December 2006, cancer-related deaths were observed in 20% of symptomatic patients with CRC. Screening colonoscopy detects colorectal cancers in the early stages. Given the favourable prognosis in these stages, screening can reduce CRC-related mortality.

Authors+Show Affiliations

Gastroenterologische Gemeinschaftspraxis Herne, Herne. Hueppe@gastro-praxis-herne.deNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Comparative Study
Evaluation Study
Journal Article

Language

ger

PubMed ID

18253898

Citation

Hüppe, D, et al. "[Effectiveness of Screening Colonoscopy in a Community-based Study]." Zeitschrift Fur Gastroenterologie, vol. 46, no. 2, 2008, pp. 193-200.
Hüppe D, Hartmann H, Felten G, et al. [Effectiveness of screening colonoscopy in a community-based study]. Z Gastroenterol. 2008;46(2):193-200.
Hüppe, D., Hartmann, H., Felten, G., Kemen, M., Tannapfel, A., Gillessen, A., & Katalinic, A. (2008). [Effectiveness of screening colonoscopy in a community-based study]. Zeitschrift Fur Gastroenterologie, 46(2), pp. 193-200. doi:10.1055/s-2007-963539.
Hüppe D, et al. [Effectiveness of Screening Colonoscopy in a Community-based Study]. Z Gastroenterol. 2008;46(2):193-200. PubMed PMID: 18253898.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - [Effectiveness of screening colonoscopy in a community-based study]. AU - Hüppe,D, AU - Hartmann,H, AU - Felten,G, AU - Kemen,M, AU - Tannapfel,A, AU - Gillessen,A, AU - Katalinic,A, PY - 2008/2/7/pubmed PY - 2008/4/19/medline PY - 2008/2/7/entrez SP - 193 EP - 200 JF - Zeitschrift fur Gastroenterologie JO - Z Gastroenterol VL - 46 IS - 2 N2 - In 2002 screening colonoscopy was introduced in Germany for the prevention of colorectal cancer (CRC) and CRC mortality. Individuals took part in a prospective study from October 2002 until September 2005 performed at a single centre for gastroenterology. Histopathological data, surgical-pathological stages and further follow-up events were recorded until 31st of December 2006. For screened individuals without symptoms, the data obtained were compared to those from age-matched patients who presented with clinical symptoms/signs and who underwent colonoscopy during the same period in time. A total of 5066 individuals underwent screening colonoscopy. In this group, colorectal cancer was detected in 46 individuals (0.9%). Endoscopic treatment was considered adequate for 21 cancers. In this group of 46 patients, 94.5% were classified into UICC stages I-II by pathological staging. In 504 screened individuals, colorectal polyps were detected (12.2%) and removed by polypectomy. Of these polyps, 16 were classified as cancer, 496 as adenomas and 1 as a carcinoid tumour. High grade dysplasia was noted in 41 polyps (8.3% of adenomas). In comparison, 4099 symptomatic patients underwent colonoscopy. In this group 100 cancers (2.4%) were detected. Advanced malignant tumours were noted in 39% of these; endoscopic treatment was feasible in 16% of the cancers. As of December 2006, cancer-related deaths were observed in 20% of symptomatic patients with CRC. Screening colonoscopy detects colorectal cancers in the early stages. Given the favourable prognosis in these stages, screening can reduce CRC-related mortality. SN - 0044-2771 UR - https://www.unboundmedicine.com/medline/citation/18253898/[Effectiveness_of_screening_colonoscopy_in_a_community_based_study]_ L2 - http://www.thieme-connect.com/DOI/DOI?10.1055/s-2007-963539 DB - PRIME DP - Unbound Medicine ER -