[Studies on chemical constituents in the buds of Tussilago farfara].Zhongguo Zhong Yao Za Zhi. 2007 Nov; 32(22):2378-81.ZZ
To study the chemical constituents in the buds of Tussilago farfara.
The chemical constituents were isolated by various column chromatographic methods and structurally elucidated by NMR and MS evidences.
Eleven compounds were obtained and identified as methyl 3, 4-O-dicaffeoylquinate (1), methyl 3, 5-O-dicaffeoylquinate (2), methyl 4, 5-O-dicaffeoylquinate (3), 3, 5-O-dicaffeoylquinic acid (4), methyl 3-O-caffeoylquinate (5), 3-O-caffeoylquinic acid (6), hyperoside (7), rutin (8), kaempferol 3-O-beta-D-glucopyranoside (9), quercetin (10), and kaempferol (11).
Compounds 2-5 were isolated from the genus for the first time.