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Premature ovarian failure and its consequences: vasomotor symptoms, sexuality, and fertility.
J Clin Oncol 2008; 26(5):753-8JC

Abstract

Premature ovarian failure is a common consequence of systemic treatment for premenopausal breast cancer. Vasomotor symptoms and sexual dysfunction occur frequently in women who have an abrupt menopause from chemotherapy or ovarian suppression. However, current fertility may be impaired even in women who are menstruating after chemotherapy, and survivors are at high risk for permanent ovarian failure at a young age. Hot flashes can be managed with venlaxafine, gabapentin, or-potentially-stress management. Providing advice on treating vaginal dryness and brief sexual counseling can often alleviate sexual dysfunction. Options for fertility preservation remain limited but are improving rapidly. Distress about interrupted childbearing has a long-term impact on the quality of life.

Authors+Show Affiliations

Department of Behavioral Science-Unit 1330, The University of Texas M.D. Anderson Cancer Center, PO Box 301439, Houston, TX 77230-1439, USA. Lschover@mdanderson.org

Pub Type(s)

Journal Article
Review

Language

eng

PubMed ID

18258983

Citation

Schover, Leslie R.. "Premature Ovarian Failure and Its Consequences: Vasomotor Symptoms, Sexuality, and Fertility." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, vol. 26, no. 5, 2008, pp. 753-8.
Schover LR. Premature ovarian failure and its consequences: vasomotor symptoms, sexuality, and fertility. J Clin Oncol. 2008;26(5):753-8.
Schover, L. R. (2008). Premature ovarian failure and its consequences: vasomotor symptoms, sexuality, and fertility. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology, 26(5), pp. 753-8. doi:10.1200/JCO.2007.14.1655.
Schover LR. Premature Ovarian Failure and Its Consequences: Vasomotor Symptoms, Sexuality, and Fertility. J Clin Oncol. 2008 Feb 10;26(5):753-8. PubMed PMID: 18258983.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Premature ovarian failure and its consequences: vasomotor symptoms, sexuality, and fertility. A1 - Schover,Leslie R, PY - 2008/2/9/pubmed PY - 2008/2/20/medline PY - 2008/2/9/entrez SP - 753 EP - 8 JF - Journal of clinical oncology : official journal of the American Society of Clinical Oncology JO - J. Clin. Oncol. VL - 26 IS - 5 N2 - Premature ovarian failure is a common consequence of systemic treatment for premenopausal breast cancer. Vasomotor symptoms and sexual dysfunction occur frequently in women who have an abrupt menopause from chemotherapy or ovarian suppression. However, current fertility may be impaired even in women who are menstruating after chemotherapy, and survivors are at high risk for permanent ovarian failure at a young age. Hot flashes can be managed with venlaxafine, gabapentin, or-potentially-stress management. Providing advice on treating vaginal dryness and brief sexual counseling can often alleviate sexual dysfunction. Options for fertility preservation remain limited but are improving rapidly. Distress about interrupted childbearing has a long-term impact on the quality of life. SN - 1527-7755 UR - https://www.unboundmedicine.com/medline/citation/18258983/Premature_ovarian_failure_and_its_consequences:_vasomotor_symptoms_sexuality_and_fertility_ L2 - http://ascopubs.org/doi/full/10.1200/JCO.2007.14.1655?url_ver=Z39.88-2003&rfr_id=ori:rid:crossref.org&rfr_dat=cr_pub=pubmed DB - PRIME DP - Unbound Medicine ER -