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Ocular and systemic factors associated with diabetes mellitus in the adult population in rural and urban China. The Beijing Eye Study.
Eye (Lond) 2009; 23(3):676-82E

Abstract

PURPOSE

To assess ocular and systemic factors associated with diabetes mellitus in the adult population in rural and urban China.

METHODS

The Beijing Eye Study 2006, a population-based, cross-sectional cohort study, included 3251 subjects aged 45 years and more (participation rate: 73.2%). Blood samples were available for 2960 (91.0%) subjects. Diabetes mellitus was defined by a fasting plasma glucose concentration >or=7.0 mmol/l or by a self-reported history diagnosis of diabetes.

RESULTS

Diabetes mellitus was found in 381 (12.9%) subjects. In binary regression analysis, the presence of diabetes mellitus was significantly associated with body mass index, systolic blood pressure, triglyceride concentrations, intraocular pressure, cylindrical refractive dioptre, presence of arteriolar sheathing, rural vsurban region, lower best-corrected visual acuity, lower high-density lipoprotein level, and lower diastolic blood pressure. It was not statistically associated with age, presence of cataract (nuclear, cortical, or subcapsular), size of the optic disc, neuroretinal rim, alphazone and betazone of peripapillary atrophy, retinal artery and vein diameters, arteriovenous nicking, focal or general narrowing, refractive error, prevalence of glaucoma, and early or late stage of age-related macular degeneration.

CONCLUSIONS

In a population-based setting, diabetes mellitus was not associated with optic disc, rim and peripapillary atrophy measurements, retinal vessel diameters, arteriovenous nicking, focal or general retinal artery narrowing, and prevalence of age-related macular degeneration. Although diabetes mellitus was significantly correlated with higher intraocular pressure, it was not associated with glaucoma.

Authors+Show Affiliations

Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China.No affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18259206

Citation

Xu, L, et al. "Ocular and Systemic Factors Associated With Diabetes Mellitus in the Adult Population in Rural and Urban China. the Beijing Eye Study." Eye (London, England), vol. 23, no. 3, 2009, pp. 676-82.
Xu L, Xie XW, Wang YX, et al. Ocular and systemic factors associated with diabetes mellitus in the adult population in rural and urban China. The Beijing Eye Study. Eye (Lond). 2009;23(3):676-82.
Xu, L., Xie, X. W., Wang, Y. X., & Jonas, J. B. (2009). Ocular and systemic factors associated with diabetes mellitus in the adult population in rural and urban China. The Beijing Eye Study. Eye (London, England), 23(3), pp. 676-82. doi:10.1038/sj.eye.6703104.
Xu L, et al. Ocular and Systemic Factors Associated With Diabetes Mellitus in the Adult Population in Rural and Urban China. the Beijing Eye Study. Eye (Lond). 2009;23(3):676-82. PubMed PMID: 18259206.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Ocular and systemic factors associated with diabetes mellitus in the adult population in rural and urban China. The Beijing Eye Study. AU - Xu,L, AU - Xie,X W, AU - Wang,Y X, AU - Jonas,J B, Y1 - 2008/02/08/ PY - 2008/2/9/pubmed PY - 2010/1/28/medline PY - 2008/2/9/entrez SP - 676 EP - 82 JF - Eye (London, England) JO - Eye (Lond) VL - 23 IS - 3 N2 - PURPOSE: To assess ocular and systemic factors associated with diabetes mellitus in the adult population in rural and urban China. METHODS: The Beijing Eye Study 2006, a population-based, cross-sectional cohort study, included 3251 subjects aged 45 years and more (participation rate: 73.2%). Blood samples were available for 2960 (91.0%) subjects. Diabetes mellitus was defined by a fasting plasma glucose concentration >or=7.0 mmol/l or by a self-reported history diagnosis of diabetes. RESULTS: Diabetes mellitus was found in 381 (12.9%) subjects. In binary regression analysis, the presence of diabetes mellitus was significantly associated with body mass index, systolic blood pressure, triglyceride concentrations, intraocular pressure, cylindrical refractive dioptre, presence of arteriolar sheathing, rural vsurban region, lower best-corrected visual acuity, lower high-density lipoprotein level, and lower diastolic blood pressure. It was not statistically associated with age, presence of cataract (nuclear, cortical, or subcapsular), size of the optic disc, neuroretinal rim, alphazone and betazone of peripapillary atrophy, retinal artery and vein diameters, arteriovenous nicking, focal or general narrowing, refractive error, prevalence of glaucoma, and early or late stage of age-related macular degeneration. CONCLUSIONS: In a population-based setting, diabetes mellitus was not associated with optic disc, rim and peripapillary atrophy measurements, retinal vessel diameters, arteriovenous nicking, focal or general retinal artery narrowing, and prevalence of age-related macular degeneration. Although diabetes mellitus was significantly correlated with higher intraocular pressure, it was not associated with glaucoma. SN - 1476-5454 UR - https://www.unboundmedicine.com/medline/citation/18259206/Ocular_and_systemic_factors_associated_with_diabetes_mellitus_in_the_adult_population_in_rural_and_urban_China__The_Beijing_Eye_Study_ L2 - http://dx.doi.org/10.1038/sj.eye.6703104 DB - PRIME DP - Unbound Medicine ER -