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Effects of ethanol extract from Saururus chinensis (Bour.) Baill on lipid and antioxidant metabolisms in rats fed a high-fat diet.
Nat Prod Res 2008; 22(3):275-83NP

Abstract

This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal + 0.5% SE), high-fat group (high-fat), high-fat group treated with 0.1% SE (high-fat + 0.1% SE), or 0.5% SE (high-fat + 0.5% SE). Weight gains showed a tendency to decrease in rat with high-fat + SE. Plasma total cholesterol showed a tendency to decrease with ethanol extract from S. chinensis (Lour.) Baill. LDL-cholesterol contents were lower in ethanol extract group than that of control group. Aspartate amino transferase and alanine amino transferase activities were increased by high-fat diet, and were decreased by 0.5% SE. Lipid peroxide level showed a tendency to increase in high-fat diet group than that of normal group. In ethanol extract from S. chinensis (Lour.) Baill groups, lipid peroxide level decreased significantly and SOD activity was also decreased progressively. These results demonstrated that the ethanol extract of S. chinensis (Lour.) Baill lowered serum cholesterol levels, tissue lipid contents and accumulation of cholesterol in the rat.

Authors+Show Affiliations

Department of Food Science and Technology and The Center for Traditional Microorganism Resources, Keimyung University, Daegu 704-701, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18266160

Citation

Yu, Mi Hee, et al. "Effects of Ethanol Extract From Saururus Chinensis (Bour.) Baill On Lipid and Antioxidant Metabolisms in Rats Fed a High-fat Diet." Natural Product Research, vol. 22, no. 3, 2008, pp. 275-83.
Yu MH, Im HG, Lee JW, et al. Effects of ethanol extract from Saururus chinensis (Bour.) Baill on lipid and antioxidant metabolisms in rats fed a high-fat diet. Nat Prod Res. 2008;22(3):275-83.
Yu, M. H., Im, H. G., Lee, J. W., Bo, M. H., Kim, H. J., Kim, S. K., ... Lee, I. S. (2008). Effects of ethanol extract from Saururus chinensis (Bour.) Baill on lipid and antioxidant metabolisms in rats fed a high-fat diet. Natural Product Research, 22(3), pp. 275-83. doi:10.1080/14786410701590657.
Yu MH, et al. Effects of Ethanol Extract From Saururus Chinensis (Bour.) Baill On Lipid and Antioxidant Metabolisms in Rats Fed a High-fat Diet. Nat Prod Res. 2008 Feb 15;22(3):275-83. PubMed PMID: 18266160.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Effects of ethanol extract from Saururus chinensis (Bour.) Baill on lipid and antioxidant metabolisms in rats fed a high-fat diet. AU - Yu,Mi Hee, AU - Im,Hyo Gwon, AU - Lee,Ji-Won, AU - Bo,Mi-Hyang Hwang, AU - Kim,Hyun-Jeong, AU - Kim,Suk Kyung, AU - Chung,Shin Kyo, AU - Lee,In-Seon, PY - 2008/2/13/pubmed PY - 2008/5/21/medline PY - 2008/2/13/entrez SP - 275 EP - 83 JF - Natural product research JO - Nat. Prod. Res. VL - 22 IS - 3 N2 - This study was performed to investigate the effect of ethanol extract from Saururus chinensis (Lour.) Baill on liver function, plasma lipid composition and antioxidant system with high-fat diet for 4 weeks. Rats were divided into the following five groups; untreated control group (normal), treated with 0.5% SE (normal + 0.5% SE), high-fat group (high-fat), high-fat group treated with 0.1% SE (high-fat + 0.1% SE), or 0.5% SE (high-fat + 0.5% SE). Weight gains showed a tendency to decrease in rat with high-fat + SE. Plasma total cholesterol showed a tendency to decrease with ethanol extract from S. chinensis (Lour.) Baill. LDL-cholesterol contents were lower in ethanol extract group than that of control group. Aspartate amino transferase and alanine amino transferase activities were increased by high-fat diet, and were decreased by 0.5% SE. Lipid peroxide level showed a tendency to increase in high-fat diet group than that of normal group. In ethanol extract from S. chinensis (Lour.) Baill groups, lipid peroxide level decreased significantly and SOD activity was also decreased progressively. These results demonstrated that the ethanol extract of S. chinensis (Lour.) Baill lowered serum cholesterol levels, tissue lipid contents and accumulation of cholesterol in the rat. SN - 1478-6419 UR - https://www.unboundmedicine.com/medline/citation/18266160/Effects_of_ethanol_extract_from_Saururus_chinensis__Bour___Baill_on_lipid_and_antioxidant_metabolisms_in_rats_fed_a_high_fat_diet_ L2 - http://www.tandfonline.com/doi/full/10.1080/14786410701590657 DB - PRIME DP - Unbound Medicine ER -