Tags

Type your tag names separated by a space and hit enter

Clinical genetics of Parkinson's disease and related disorders.
Parkinsonism Relat Disord 2007; 13 Suppl 3:S229-32PR

Abstract

Our knowledge regarding the genetics of Parkinson's disease (PD) and parkinsonism has evolved dramatically during the past decade, with the discovery of numerous loci and genes. The LRRK2 gene has emerged as the most commonly involved in both familial and sporadic PD. Several variants in LRRK2 and SNCA have been associated with an increased risk of sporadic PD. PRKN, PINK1 and DJ1 mutations cause early-onset recessively inherited PD. Autosomal dominant dementia and parkinsonism is caused by mutations in the MAPT gene, and in the most recently discovered PGRN gene.

Authors+Show Affiliations

Department of Neurology, Mayo Clinic, Jacksonville, FL 32224, USA.No affiliation info available

Pub Type(s)

Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review

Language

eng

PubMed ID

18267241

Citation

Wider, Christian, and Zbigniew K. Wszolek. "Clinical Genetics of Parkinson's Disease and Related Disorders." Parkinsonism & Related Disorders, vol. 13 Suppl 3, 2007, pp. S229-32.
Wider C, Wszolek ZK. Clinical genetics of Parkinson's disease and related disorders. Parkinsonism Relat Disord. 2007;13 Suppl 3:S229-32.
Wider, C., & Wszolek, Z. K. (2007). Clinical genetics of Parkinson's disease and related disorders. Parkinsonism & Related Disorders, 13 Suppl 3, pp. S229-32. doi:10.1016/S1353-8020(08)70007-5.
Wider C, Wszolek ZK. Clinical Genetics of Parkinson's Disease and Related Disorders. Parkinsonism Relat Disord. 2007;13 Suppl 3:S229-32. PubMed PMID: 18267241.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Clinical genetics of Parkinson's disease and related disorders. AU - Wider,Christian, AU - Wszolek,Zbigniew K, PY - 2008/11/19/pubmed PY - 2009/4/2/medline PY - 2008/11/19/entrez SP - S229 EP - 32 JF - Parkinsonism & related disorders JO - Parkinsonism Relat. Disord. VL - 13 Suppl 3 N2 - Our knowledge regarding the genetics of Parkinson's disease (PD) and parkinsonism has evolved dramatically during the past decade, with the discovery of numerous loci and genes. The LRRK2 gene has emerged as the most commonly involved in both familial and sporadic PD. Several variants in LRRK2 and SNCA have been associated with an increased risk of sporadic PD. PRKN, PINK1 and DJ1 mutations cause early-onset recessively inherited PD. Autosomal dominant dementia and parkinsonism is caused by mutations in the MAPT gene, and in the most recently discovered PGRN gene. SN - 1353-8020 UR - https://www.unboundmedicine.com/medline/citation/18267241/Clinical_genetics_of_Parkinson's_disease_and_related_disorders_ L2 - https://linkinghub.elsevier.com/retrieve/pii/S1353-8020(08)70007-5 DB - PRIME DP - Unbound Medicine ER -