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Meta and para effects in the ultrafast excited-state dynamics of the green fluorescent protein chromophores.
J Phys Chem B. 2008 Mar 06; 112(9):2700-11.JP

Abstract

Femtosecond transient absorption and fluorescence upconversion experiments have been performed to investigate the photoinduced dynamics of the meta isomer of the green fluorescent protein chromophore, m-HBDI, and its O-methylated derivative, m-MeOBDI, in various solvent mixtures at neutral, acidic, and basic pH. The para isomer, p-HBDI, and its O- and N-methylated derivatives, p-MeOBDI and p-HBDIMe(+), were also studied for comparison. In all cases, fast quenching of the excited S1 state by internal conversion (IC) to the ground state was observed. In the para compounds, IC, presumably promoted by the internal twisting, arises in <1 ps. A similar process takes place in the meta compounds in nonaqueous solvents but with notably slower kinetics. In aqueous solutions, the meta compounds undergo ultrafast intermolecular excited-state proton transfer that competes with isomerization.

Authors+Show Affiliations

School of Chemistry and Biochemistry, Georgia Institute of Technology, Atlanta, Georgia 30332-0400, USA. solntsev@gatech.eduNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

18269276

Citation

Solntsev, Kyril M., et al. "Meta and Para Effects in the Ultrafast Excited-state Dynamics of the Green Fluorescent Protein Chromophores." The Journal of Physical Chemistry. B, vol. 112, no. 9, 2008, pp. 2700-11.
Solntsev KM, Poizat O, Dong J, et al. Meta and para effects in the ultrafast excited-state dynamics of the green fluorescent protein chromophores. J Phys Chem B. 2008;112(9):2700-11.
Solntsev, K. M., Poizat, O., Dong, J., Rehault, J., Lou, Y., Burda, C., & Tolbert, L. M. (2008). Meta and para effects in the ultrafast excited-state dynamics of the green fluorescent protein chromophores. The Journal of Physical Chemistry. B, 112(9), 2700-11. https://doi.org/10.1021/jp077707t
Solntsev KM, et al. Meta and Para Effects in the Ultrafast Excited-state Dynamics of the Green Fluorescent Protein Chromophores. J Phys Chem B. 2008 Mar 6;112(9):2700-11. PubMed PMID: 18269276.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Meta and para effects in the ultrafast excited-state dynamics of the green fluorescent protein chromophores. AU - Solntsev,Kyril M, AU - Poizat,Olivier, AU - Dong,Jian, AU - Rehault,Julien, AU - Lou,Yongbing, AU - Burda,Clemens, AU - Tolbert,Laren M, Y1 - 2008/02/13/ PY - 2008/2/14/pubmed PY - 2008/4/25/medline PY - 2008/2/14/entrez SP - 2700 EP - 11 JF - The journal of physical chemistry. B JO - J Phys Chem B VL - 112 IS - 9 N2 - Femtosecond transient absorption and fluorescence upconversion experiments have been performed to investigate the photoinduced dynamics of the meta isomer of the green fluorescent protein chromophore, m-HBDI, and its O-methylated derivative, m-MeOBDI, in various solvent mixtures at neutral, acidic, and basic pH. The para isomer, p-HBDI, and its O- and N-methylated derivatives, p-MeOBDI and p-HBDIMe(+), were also studied for comparison. In all cases, fast quenching of the excited S1 state by internal conversion (IC) to the ground state was observed. In the para compounds, IC, presumably promoted by the internal twisting, arises in <1 ps. A similar process takes place in the meta compounds in nonaqueous solvents but with notably slower kinetics. In aqueous solutions, the meta compounds undergo ultrafast intermolecular excited-state proton transfer that competes with isomerization. SN - 1520-6106 UR - https://www.unboundmedicine.com/medline/citation/18269276/Meta_and_para_effects_in_the_ultrafast_excited_state_dynamics_of_the_green_fluorescent_protein_chromophores_ L2 - https://doi.org/10.1021/jp077707t DB - PRIME DP - Unbound Medicine ER -