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Assessment of left ventricular diastolic function and Tei index by tissue Doppler imaging in patients with Cushing's Syndrome.
Echocardiography. 2008 Feb; 25(2):182-90.E

Abstract

BACKGROUND

The aim of this study was to assess left ventricular (LV) function and the Tei index by tissue Doppler imaging (TDI), and also to evaluate the relationship of serum cortisol level with the Tei index and LV function in patients with Cushing's Syndrome (CS).

METHODS

We prospectively evaluated 22 patients with CS and 23 control subjects. LV function was assessed by echocardiography. Early diastolic (Em), late diastolic (Am), peak systolic (Sm), mitral annular velocities, Em/Am, the Tei index, and E/Em were calculated by TDI. Mitral inflow velocities, color M-mode flow propagation velocity (Vp), relative wall thickness (RWT), and LV mass index (LVMI) were assessed by two-dimensional echocardiography.

RESULT

Peak (E) velocity and the ratio of E to peak late (A) velocity (E/A) were lower in those with CS than in those without. Patients with CS had significantly higher RWT, IVRT, and LVMI than those controls. Vp was lower in the CS-patients than that in control subjects. Em and Em/Am were lower in patients with CS than those in controls. In patients with CS, the Tei index was significantly higher than control subjects.

CONCLUSION

Serum cortisol level was positively correlated with the Tei index and E/Em ratio but negatively correlated with Em, Sm, and EF only in patients with CS. Serum cortisol level positively correlated with the Tei index and E/Em ratio but negatively correlated with Em, EF, and Sm. The parameters obtained from lateral mitral annulus by TDI can be used for identification of LV diastolic dysfunction in patients with CS.

Authors+Show Affiliations

KTU Faculty of Medicine, Departments of Cardiology, Trabzon-Turkey. merihbaykan@yahoo.comNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article

Language

eng

PubMed ID

18269563

Citation

Baykan, Merih, et al. "Assessment of Left Ventricular Diastolic Function and Tei Index By Tissue Doppler Imaging in Patients With Cushing's Syndrome." Echocardiography (Mount Kisco, N.Y.), vol. 25, no. 2, 2008, pp. 182-90.
Baykan M, Erem C, Gedikli O, et al. Assessment of left ventricular diastolic function and Tei index by tissue Doppler imaging in patients with Cushing's Syndrome. Echocardiography. 2008;25(2):182-90.
Baykan, M., Erem, C., Gedikli, O., Hacihasanoglu, A., Erdogan, T., Kocak, M., Kaplan, S., Kiriş, A., Orem, C., & Celik, S. (2008). Assessment of left ventricular diastolic function and Tei index by tissue Doppler imaging in patients with Cushing's Syndrome. Echocardiography (Mount Kisco, N.Y.), 25(2), 182-90. https://doi.org/10.1111/j.1540-8175.2007.00572.x
Baykan M, et al. Assessment of Left Ventricular Diastolic Function and Tei Index By Tissue Doppler Imaging in Patients With Cushing's Syndrome. Echocardiography. 2008;25(2):182-90. PubMed PMID: 18269563.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Assessment of left ventricular diastolic function and Tei index by tissue Doppler imaging in patients with Cushing's Syndrome. AU - Baykan,Merih, AU - Erem,Cihangir, AU - Gedikli,Omer, AU - Hacihasanoglu,Arif, AU - Erdogan,Turan, AU - Kocak,Mustafa, AU - Kaplan,Sahin, AU - Kiriş,Abdulkadir, AU - Orem,Cihan, AU - Celik,Sükrü, PY - 2008/2/14/pubmed PY - 2008/6/5/medline PY - 2008/2/14/entrez SP - 182 EP - 90 JF - Echocardiography (Mount Kisco, N.Y.) JO - Echocardiography VL - 25 IS - 2 N2 - BACKGROUND: The aim of this study was to assess left ventricular (LV) function and the Tei index by tissue Doppler imaging (TDI), and also to evaluate the relationship of serum cortisol level with the Tei index and LV function in patients with Cushing's Syndrome (CS). METHODS: We prospectively evaluated 22 patients with CS and 23 control subjects. LV function was assessed by echocardiography. Early diastolic (Em), late diastolic (Am), peak systolic (Sm), mitral annular velocities, Em/Am, the Tei index, and E/Em were calculated by TDI. Mitral inflow velocities, color M-mode flow propagation velocity (Vp), relative wall thickness (RWT), and LV mass index (LVMI) were assessed by two-dimensional echocardiography. RESULT: Peak (E) velocity and the ratio of E to peak late (A) velocity (E/A) were lower in those with CS than in those without. Patients with CS had significantly higher RWT, IVRT, and LVMI than those controls. Vp was lower in the CS-patients than that in control subjects. Em and Em/Am were lower in patients with CS than those in controls. In patients with CS, the Tei index was significantly higher than control subjects. CONCLUSION: Serum cortisol level was positively correlated with the Tei index and E/Em ratio but negatively correlated with Em, Sm, and EF only in patients with CS. Serum cortisol level positively correlated with the Tei index and E/Em ratio but negatively correlated with Em, EF, and Sm. The parameters obtained from lateral mitral annulus by TDI can be used for identification of LV diastolic dysfunction in patients with CS. SN - 0742-2822 UR - https://www.unboundmedicine.com/medline/citation/18269563/Assessment_of_left_ventricular_diastolic_function_and_Tei_index_by_tissue_Doppler_imaging_in_patients_with_Cushing's_Syndrome_ L2 - https://doi.org/10.1111/j.1540-8175.2007.00572.x DB - PRIME DP - Unbound Medicine ER -