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Adaptation of dialectical behavior therapy skills training group for treatment-resistant depression.
J Nerv Ment Dis. 2008 Feb; 196(2):136-43.JN

Abstract

Treatment resistant depression is common, persistent, and results in substantial functional and social impairment. This study describes the development and preliminary outcome evaluation of a dialectical behavior therapy-based skills training group to treat depressive symptoms in adult outpatients for whom antidepressant medication had not produced remission. The 16-session, once-weekly group covered the 4 dialectical behavior therapy skill sets: mindfulness, interpersonal effectiveness, emotion regulation, and distress tolerance. Twenty-four patients with ongoing depressive symptoms despite stable, adequate medication treatment for major depressive disorder were randomly assigned to either the skills group or a wait-list condition. The depressive symptoms of participants who completed the study (9 wait-list participants, 10 skills group participants) were compared using a clinician-rated Hamilton rating scale for depression and then replicated using a self-report measure Beck depression inventory. Clinician raters were blind to each participant's assigned study condition. Skills group participants showed significantly greater improvements in depressive symptoms compared with the control condition. Effect sizes were large for both measures of depression (Cohen's d = 1.45 for Hamilton rating scale for depression and 1.31 for Beck depression inventory), suggesting that larger scale trials are warranted.

Authors+Show Affiliations

Department of Psychiatry, Massachusetts General Hospital, Boston, Massachusetts 02114, USA. rharley@partners.orgNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Randomized Controlled Trial
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18277222

Citation

Harley, Rebecca, et al. "Adaptation of Dialectical Behavior Therapy Skills Training Group for Treatment-resistant Depression." The Journal of Nervous and Mental Disease, vol. 196, no. 2, 2008, pp. 136-43.
Harley R, Sprich S, Safren S, et al. Adaptation of dialectical behavior therapy skills training group for treatment-resistant depression. J Nerv Ment Dis. 2008;196(2):136-43.
Harley, R., Sprich, S., Safren, S., Jacobo, M., & Fava, M. (2008). Adaptation of dialectical behavior therapy skills training group for treatment-resistant depression. The Journal of Nervous and Mental Disease, 196(2), 136-43. https://doi.org/10.1097/NMD.0b013e318162aa3f
Harley R, et al. Adaptation of Dialectical Behavior Therapy Skills Training Group for Treatment-resistant Depression. J Nerv Ment Dis. 2008;196(2):136-43. PubMed PMID: 18277222.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Adaptation of dialectical behavior therapy skills training group for treatment-resistant depression. AU - Harley,Rebecca, AU - Sprich,Susan, AU - Safren,Steven, AU - Jacobo,Michelle, AU - Fava,Maurizio, PY - 2008/2/16/pubmed PY - 2008/3/8/medline PY - 2008/2/16/entrez SP - 136 EP - 43 JF - The Journal of nervous and mental disease JO - J. Nerv. Ment. Dis. VL - 196 IS - 2 N2 - Treatment resistant depression is common, persistent, and results in substantial functional and social impairment. This study describes the development and preliminary outcome evaluation of a dialectical behavior therapy-based skills training group to treat depressive symptoms in adult outpatients for whom antidepressant medication had not produced remission. The 16-session, once-weekly group covered the 4 dialectical behavior therapy skill sets: mindfulness, interpersonal effectiveness, emotion regulation, and distress tolerance. Twenty-four patients with ongoing depressive symptoms despite stable, adequate medication treatment for major depressive disorder were randomly assigned to either the skills group or a wait-list condition. The depressive symptoms of participants who completed the study (9 wait-list participants, 10 skills group participants) were compared using a clinician-rated Hamilton rating scale for depression and then replicated using a self-report measure Beck depression inventory. Clinician raters were blind to each participant's assigned study condition. Skills group participants showed significantly greater improvements in depressive symptoms compared with the control condition. Effect sizes were large for both measures of depression (Cohen's d = 1.45 for Hamilton rating scale for depression and 1.31 for Beck depression inventory), suggesting that larger scale trials are warranted. SN - 1539-736X UR - https://www.unboundmedicine.com/medline/citation/18277222/Adaptation_of_dialectical_behavior_therapy_skills_training_group_for_treatment_resistant_depression_ L2 - http://dx.doi.org/10.1097/NMD.0b013e318162aa3f DB - PRIME DP - Unbound Medicine ER -