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Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory.
Neuroreport 2008; 19(1):43-7N

Abstract

The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed before, during, and 30 min after 1 mA anodal or sham tDCS. Anodal tDCS, compared with sham stimulation, significantly improved working-memory performance. Accuracy of response was significantly increased after 20 min of tDCS application, and was further enhanced after 30 min of stimulation. This effect was maintained for 30 min after the completion of stimulation. These results suggest that tDCS at 1 mA enhances working memory in a time-dependent manner for at least 30 min in healthy participants.

Authors+Show Affiliations

Department of Physical Medicine and Rehabilitation, Division for Neurorehabilitation, Samsung Medical Center, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.No affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info availableNo affiliation info available

Pub Type(s)

Clinical Trial
Journal Article
Research Support, Non-U.S. Gov't

Language

eng

PubMed ID

18281890

Citation

Ohn, Suk Hoon, et al. "Time-dependent Effect of Transcranial Direct Current Stimulation On the Enhancement of Working Memory." Neuroreport, vol. 19, no. 1, 2008, pp. 43-7.
Ohn SH, Park CI, Yoo WK, et al. Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory. Neuroreport. 2008;19(1):43-7.
Ohn, S. H., Park, C. I., Yoo, W. K., Ko, M. H., Choi, K. P., Kim, G. M., ... Kim, Y. H. (2008). Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory. Neuroreport, 19(1), pp. 43-7. doi:10.1097/WNR.0b013e3282f2adfd.
Ohn SH, et al. Time-dependent Effect of Transcranial Direct Current Stimulation On the Enhancement of Working Memory. Neuroreport. 2008 Jan 8;19(1):43-7. PubMed PMID: 18281890.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Time-dependent effect of transcranial direct current stimulation on the enhancement of working memory. AU - Ohn,Suk Hoon, AU - Park,Chang-Il, AU - Yoo,Woo-Kyoung, AU - Ko,Myoung-Hwan, AU - Choi,Kyung Pil, AU - Kim,Gyeong-Moon, AU - Lee,Yong Taek, AU - Kim,Yun-Hee, PY - 2008/2/19/pubmed PY - 2008/4/12/medline PY - 2008/2/19/entrez SP - 43 EP - 7 JF - Neuroreport JO - Neuroreport VL - 19 IS - 1 N2 - The time-dependent effect of transcranial direct current stimulation (tDCS) on working memory was investigated by applying anodal stimulation over the left prefrontal cortex. This single-blind, sham-controlled crossover study recruited 15 healthy participants. A three-back verbal working-memory task was performed before, during, and 30 min after 1 mA anodal or sham tDCS. Anodal tDCS, compared with sham stimulation, significantly improved working-memory performance. Accuracy of response was significantly increased after 20 min of tDCS application, and was further enhanced after 30 min of stimulation. This effect was maintained for 30 min after the completion of stimulation. These results suggest that tDCS at 1 mA enhances working memory in a time-dependent manner for at least 30 min in healthy participants. SN - 0959-4965 UR - https://www.unboundmedicine.com/medline/citation/18281890/Time_dependent_effect_of_transcranial_direct_current_stimulation_on_the_enhancement_of_working_memory_ L2 - http://dx.doi.org/10.1097/WNR.0b013e3282f2adfd DB - PRIME DP - Unbound Medicine ER -