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Pregnancy, birth, and infant health outcomes from the National Smallpox Vaccine in Pregnancy Registry, 2003-2006.
Clin Infect Dis. 2008 Mar 15; 46 Suppl 3:S221-6.CI

Abstract

When the United States implemented civilian and military smallpox vaccination programs in 2003, the National Smallpox Vaccine in Pregnancy Registry was established to better evaluate outcomes after the inadvertent vaccination of pregnant women. Women were referred to the registry by vaccine administrators, health care providers, or state health departments or through self-referral. Registry professionals actively follow up with all enrolled women and collect data on pregnancy, birth, and infant health outcomes. As of September 2006, pregnancy outcome data were available from 376 women. Most (77%) were vaccinated near the time of conception, before results of a standard pregnancy test would have been positive. To date, outcome evaluations have not revealed higher-than-expected rates of pregnancy loss (11.9%), preterm birth (10.7%), or birth defects (2.8%), compared with those in healthy referent populations. No cases of fetal vaccinia have been identified. The Smallpox Vaccine in Pregnancy Registry continues to actively enroll women and follow infant and early-childhood health outcomes.

Authors+Show Affiliations

Department of Defense Center for Deployment Health Research, Naval Health Research Center, San Diego, California, USA. margaret.ryan@med.navy.milNo affiliation info availableNo affiliation info available

Pub Type(s)

Journal Article
Research Support, U.S. Gov't, Non-P.H.S.

Language

eng

PubMed ID

18284362

Citation

Ryan, Margaret A K., et al. "Pregnancy, Birth, and Infant Health Outcomes From the National Smallpox Vaccine in Pregnancy Registry, 2003-2006." Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, vol. 46 Suppl 3, 2008, pp. S221-6.
Ryan MA, Seward JF, Smallpox Vaccine in Pregnancy Registry Team. Pregnancy, birth, and infant health outcomes from the National Smallpox Vaccine in Pregnancy Registry, 2003-2006. Clin Infect Dis. 2008;46 Suppl 3:S221-6.
Ryan, M. A., & Seward, J. F. (2008). Pregnancy, birth, and infant health outcomes from the National Smallpox Vaccine in Pregnancy Registry, 2003-2006. Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America, 46 Suppl 3, S221-6. https://doi.org/10.1086/524744
Ryan MA, Seward JF, Smallpox Vaccine in Pregnancy Registry Team. Pregnancy, Birth, and Infant Health Outcomes From the National Smallpox Vaccine in Pregnancy Registry, 2003-2006. Clin Infect Dis. 2008 Mar 15;46 Suppl 3:S221-6. PubMed PMID: 18284362.
* Article titles in AMA citation format should be in sentence-case
TY - JOUR T1 - Pregnancy, birth, and infant health outcomes from the National Smallpox Vaccine in Pregnancy Registry, 2003-2006. AU - Ryan,Margaret A K, AU - Seward,Jane F, AU - ,, PY - 2008/3/20/pubmed PY - 2008/4/5/medline PY - 2008/3/20/entrez SP - S221 EP - 6 JF - Clinical infectious diseases : an official publication of the Infectious Diseases Society of America JO - Clin Infect Dis VL - 46 Suppl 3 N2 - When the United States implemented civilian and military smallpox vaccination programs in 2003, the National Smallpox Vaccine in Pregnancy Registry was established to better evaluate outcomes after the inadvertent vaccination of pregnant women. Women were referred to the registry by vaccine administrators, health care providers, or state health departments or through self-referral. Registry professionals actively follow up with all enrolled women and collect data on pregnancy, birth, and infant health outcomes. As of September 2006, pregnancy outcome data were available from 376 women. Most (77%) were vaccinated near the time of conception, before results of a standard pregnancy test would have been positive. To date, outcome evaluations have not revealed higher-than-expected rates of pregnancy loss (11.9%), preterm birth (10.7%), or birth defects (2.8%), compared with those in healthy referent populations. No cases of fetal vaccinia have been identified. The Smallpox Vaccine in Pregnancy Registry continues to actively enroll women and follow infant and early-childhood health outcomes. SN - 1537-6591 UR - https://www.unboundmedicine.com/medline/citation/18284362/Pregnancy_birth_and_infant_health_outcomes_from_the_National_Smallpox_Vaccine_in_Pregnancy_Registry_2003_2006_ L2 - https://academic.oup.com/cid/article-lookup/doi/10.1086/524744 DB - PRIME DP - Unbound Medicine ER -